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Mixed-integer programming (MIP) is a well-established framework for computer-aided molecular design (CAMD). By precisely encoding the molecular space and score functions, e.g., a graph neural network, the molecular design problem is…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Shiqiang Zhang , Christian W. Feldmann , Frederik Sandfort , Miriam Mathea , Juan S. Campos , Ruth Misener

Cooper is an open-source package for solving constrained optimization problems involving deep learning models. Cooper implements several Lagrangian-based first-order update schemes, making it easy to combine constrained optimization…

Machine Learning · Computer Science 2025-04-03 Jose Gallego-Posada , Juan Ramirez , Meraj Hashemizadeh , Simon Lacoste-Julien

Mixed Integer Programming (MIP) solvers rely on an array of sophisticated heuristics developed with decades of research to solve large-scale MIP instances encountered in practice. Machine learning offers to automatically construct better…

Mathematical software systems are becoming more and more important in pure and applied mathematics in order to deal with the complexity and scalability issues inherent in mathematics. In the last decades we have seen a cambric explosion of…

Mathematical Software · Computer Science 2020-02-13 Katja Bercic , Jacques Carette , William M. Farmer , Michael Kohlhase , Dennis Müller , Florian Rabe , Yasmine Sharoda

Global optimization of decision trees is a long-standing challenge in combinatorial optimization, yet such models play an important role in interpretable machine learning. Although the problem has been investigated for several decades, only…

Machine Learning · Computer Science 2026-02-03 Jiancheng Tu , Wenqi Fan , Zhibin Wu

Scientific advancement relies on the ability to share and reproduce results. When data analysis or calculations are carried out using software written by scientists there are special challenges around code versions, quality and code…

Software Engineering · Computer Science 2025-07-09 S. Lee , C. Myers , A. Yang , T. Zhang , S. J. L. Billinge

PEPit is a Python package aiming at simplifying the access to worst-case analyses of a large family of first-order optimization methods possibly involving gradient, projection, proximal, or linear optimization oracles, along with their…

Optimization and Control · Mathematics 2024-06-18 Baptiste Goujaud , Céline Moucer , François Glineur , Julien Hendrickx , Adrien Taylor , Aymeric Dieuleveut

Scipp is heavily inspired by the Python library xarray. It enriches raw NumPy-like multi-dimensional arrays of data by adding named dimensions and associated coordinates. Multiple arrays are combined into datasets. On top of this, scipp…

Mathematical Software · Computer Science 2020-10-02 Simon Heybrock , Owen Arnold , Igor Gudich , Daniel Nixon , Neil Vaytet

High-Performance Computing (HPC) platforms enable scientific software to achieve breakthroughs in many research fields such as physics, biology, and chemistry, by employing Research Software Engineering (RSE) techniques. These include 1)…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-16 Matan Rusanovsky , Re'em Harel , Lee-or Alon , Idan Mosseri , Harel Levin , Gal Oren

Incremental computation aims to compute more efficiently on changed input by reusing previously computed results. We give a high-level overview of works on incremental computation, and highlight the essence underlying all of them, which we…

Programming Languages · Computer Science 2025-10-15 Yanhong A. Liu

The Core Imaging Library (CIL) is an open-source versatile Python framework for solving inverse problems with special emphasis on imaging applications such as computed tomography (CT), using a plug-in architecture for data and operators,…

Applications integrating analysis components require a programmable interface which defines statistical operations independently of any programming language. By separating concerns of scientific computing from application and implementation…

Computation · Statistics 2014-06-19 Jeroen Ooms

This paper is an overview of Image Processing and Analysis using Scilab, a free prototyping environment for numerical calculations similar to Matlab. We demonstrate the capabilities of SIP -- the Scilab Image Processing Toolbox -- which…

Mathematical Software · Computer Science 2012-03-20 Ricardo Fabbri , Odemir Martinez Bruno , Luciano da Fontoura Costa

A numerical method is developed to solve linear semi-infinite programming problem (LSIP) in which the iterates produced by the algorithm are feasible for the original problem. This is achieved by constructing a sequence of standard linear…

Optimization and Control · Mathematics 2021-01-26 Shuxiong Wang

Mathematical optimization is one of the cornerstones of modern engineering research and practice. Yet, throughout all application domains, mathematical optimization is, for the most part, considered to be a numerical discipline.…

Optimization and Control · Mathematics 2024-01-09 Adrian Hauswirth , Zhiyu He , Saverio Bolognani , Gabriela Hug , Florian Dörfler

High Performance Distributed Computing is essential to boost scientific progress in many areas of science and to efficiently deploy a number of complex scientific applications. These applications have different characteristics that require…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-12-04 Mariza Ferro , Antonio R. Mury , Laion F. Manfroi , Bruno Schlze

A portion of the HEP community has perceived the need for a minimization package written in C++ and taking advantage of the Object-Oriented nature of that langauge. To be acceptable for HEP, such a package must at least encompass all the…

High Energy Physics - Phenomenology · Physics 2008-11-26 Mark Fischler , David Sachs

Research software -- specialist software used to support or undertake research -- is of huge importance to researchers. It contributes to significant advances in the wider world and requires collaboration between people with diverse skills…

Software Engineering · Computer Science 2021-06-22 Neil P. Chue Hong , Jeremy Cohen , Caroline Jay

Constraint programming is used for a variety of real-world optimisation problems, such as planning, scheduling and resource allocation problems. At the same time, one continuously gathers vast amounts of data about these problems. Current…

In recent years, quantum, quantum-inspired, and hybrid algorithms are increasingly showing promise for solving software engineering optimization problems. However, best-intended practices for conducting empirical studies have not yet well…

Software Engineering · Computer Science 2025-11-03 Man Zhang , Yuechen Li , Tao Yue , Kai-Yuan Cai