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Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

We assessed the benefit of combining stress cardiac CT perfusion (CCTP) myocardial blood flow (MBF) with coronary CT angiography (CCTA) using our innovative CCTP software. By combining CCTA and CCTP, one can uniquely identify a flow…

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Analysing coronary artery plaque segments with respect to their functional significance and therefore their influence to patient management in a non-invasive setup is an important subject of current research. In this work we compare and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-16 Felix Denzinger , Michael Wels , Katharina Breininger , Anika Reidelshöfer , Joachim Eckert , Michael Sühling , Axel Schmermund , Andreas Maier

In patients with obstructive coronary artery disease, the functional significance of a coronary artery stenosis needs to be determined to guide treatment. This is typically established through fractional flow reserve (FFR) measurement,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Majd Zreik , Robbert W. van Hamersvelt , Nadieh Khalili , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Optical Coherence Tomography Angiography (OCTA) is a crucial imaging technique for visualizing retinal vasculature and diagnosing eye diseases such as diabetic retinopathy and glaucoma. However, precise segmentation of OCTA vasculature…

Image and Video Processing · Electrical Eng. & Systems 2025-01-03 Shun Zou , Zhuo Zhang , Guangwei Gao

Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

Optical coherence tomography angiography (OCTA) is an imaging technique that allows for non-invasive investigation of the microvasculature in the retina. OCTA uses laser light reflectance to measure moving blood cells. Hereby, it visualizes…

Tissues and Organs · Quantitative Biology 2020-02-11 Astrid M. E. Engberg , Vedrana A. Dahl , Anders B. Dahl

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

CAD remains a major global public health burden, yet scalable screening tools are limited. Although CCTA is a first-line non-invasive diagnostic modality, its use is constrained by resource requirements and radiation exposure. AI-ECG may…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Yujie Xiao , Qinghao Zhao , Gongzheng Tang , Hao Zhang , Zhuoran Kan , Deyun Zhang , Jun Li , Guangkun Nie , Xiaocheng Fang , Haoyu Wang , Shun Huang , Tong Liu , Jian Liu , Kangyin Chen , Shenda Hong

Optical coherence tomography angiography (OCTA) can non-invasively image the eye's circulatory system. In order to reliably characterize the retinal vasculature, there is a need to automatically extract quantitative metrics from these…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Martin J. Menten , Johannes C. Paetzold , Alina Dima , Bjoern H. Menze , Benjamin Knier , Daniel Rueckert

Background: Computed Tomography Angiography (CTA) is crucial for cerebrovascular disease diagnosis. Dynamic CTA is a type of imaging that captures temporal information about the We aim to develop and evaluate two segmentation techniques to…

Medical Physics · Physics 2025-02-17 Shrikanth Yadav , Jisoo Kim , Geoffrey Young , Lei Qin

Coronary angiography is the gold standard imaging technique for studying and diagnosing coronary artery disease. However, the resulting 2D X-ray projections lose 3D information and exhibit visual ambiguities. In this work, we aim to…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Yifan Wu , Rohit Jena , Mehmet Gulsun , Vivek Singh , Puneet Sharma , James C. Gee

The presence of plaques in the coronary arteries is a major risk to the patients' life. In particular, non-calcified plaques pose a great challenge, as they are harder to detect and more likely to rupture than calcified plaques. While…

Coronary CT angiography (CCTA) and intravascular ultrasound (IVUS) provide complementary information for coronary artery disease assessment, making their registration valuable for comprehensive analysis. However, existing registration…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 R. L. M. van Herten , José P. Henriques , R. Nils Planken , Joost Daemen , Eline M. J. Hartman , Jolanda J. Wentzel , Ivana Išgum

Coronary artery disease (CAD) remains a prevalent cardiovascular condition, posing significant health risks worldwide. This pathology, characterized by plaque accumulation in coronary artery walls, leads to myocardial ischemia and various…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Xinyun Liu , Chen Zhao

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

Medical Physics · Physics 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

Providing closed and well-connected boundaries of coronary artery is essential to assist cardiologists in the diagnosis of coronary artery disease (CAD). Recently, several deep learning-based methods have been proposed for boundary…

Compared with other imaging modalities, intravascular optical coherence tomography (IVOCT) has significant advantages for guiding percutaneous coronary interventions. To aid IVOCT research studies, we developed the Optical Coherence…