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We present EHRMIND, a practical recipe for adapting large language models (LLMs) to complex clinical reasoning tasks using reinforcement learning with verifiable rewards (RLVR). While RLVR has succeeded in mathematics and coding, its…

Computation and Language · Computer Science 2025-06-02 Jiacheng Lin , Zhenbang Wu , Jimeng Sun

Reliable seizure detection is critical for diagnosing and managing epilepsy, yet clinical workflows remain dependent on time-consuming manual EEG interpretation. While machine learning has shown promise, existing approaches often rely on…

Machine Learning · Computer Science 2025-08-12 Bartlomiej Chybowski , Shima Abdullateef , Hollan Haule , Alfredo Gonzalez-Sulser , Javier Escudero

The Internet of Medical Things transcends traditional medical boundaries, enabling a transition from reactive treatment to proactive prevention. This innovative method revolutionizes healthcare by facilitating early disease detection and…

Cryptography and Security · Computer Science 2025-09-04 Ayoub Si-ahmed , Mohammed Ali Al-Garadi , Narhimene Boustia

With the advancements in computer technology, there is a rapid development of intelligent systems to understand the complex relationships in data to make predictions and classifications. Artificail Intelligence based framework is rapidly…

Machine Learning · Computer Science 2021-07-30 G Jignesh Chowdary , Suganya G , Premalatha M , Asnath Victy Phamila Y , Karunamurthy K

This paper discusses the latest generation of the MONARC (MOdels of Networked Analysis at Regional Centers) simulation framework, as a design and modelling tool for large scale distributed systems applied to HEP experiments. A…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-06-28 Ciprian Dobre , Corina Stratan

Structured Electronic Health Record (EHR) data stores patient information in relational tables and plays a central role in clinical decision-making. Recent advances have explored the use of large language models (LLMs) to process such data,…

Artificial Intelligence · Computer Science 2026-04-02 Xiao Yang , Xuejiao Zhao , Zhiqi Shen

The objective of drug discovery is to identify chemical compounds that possess specific pharmaceutical properties toward a binding target. Existing large language models (LLMS) can achieve high token matching scores in terms of likelihood…

Machine Learning · Computer Science 2025-04-01 Xuefeng Liu , Chih-chan Tien , Peng Ding , Songhao Jiang , Rick L. Stevens

After a machine learning (ML)-based system is deployed, monitoring its performance is important to ensure the safety and effectiveness of the algorithm over time. When an ML algorithm interacts with its environment, the algorithm can affect…

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Domain gaps are among the most relevant roadblocks in the clinical translation of machine learning (ML)-based solutions for medical image analysis. While current research focuses on new training paradigms and network architectures, little…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Patrick Godau , Piotr Kalinowski , Evangelia Christodoulou , Annika Reinke , Minu Tizabi , Luciana Ferrer , Paul Jäger , Lena Maier-Hein

The machine learning lifecycle extends beyond the deployment stage. Monitoring deployed models is crucial for continued provision of high quality machine learning enabled services. Key areas include model performance and data monitoring,…

Machine Learning · Statistics 2020-07-14 Janis Klaise , Arnaud Van Looveren , Clive Cox , Giovanni Vacanti , Alexandru Coca

Machine Learning Operations (MLOps) is becoming a highly crucial part of businesses looking to capitalize on the benefits of AI and ML models. This research presents a detailed review of MLOps, its benefits, difficulties, evolutions, and…

Software Engineering · Computer Science 2023-06-01 A. I. Ullah Tabassam

Today, massive amounts of streaming data from smart devices need to be analyzed automatically to realize the Internet of Things. The Complex Event Processing (CEP) paradigm promises low-latency pattern detection on event streams. However,…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-27 Christian Mayer , Ruben Mayer , Majd Abdo

Reinforcement Learning (RL) offers a powerful framework for optimizing dynamic treatment regimes (DTRs). However, clinical RL is fundamentally bottlenecked by reward engineering: the challenge of defining signals that safely and effectively…

Machine Learning · Computer Science 2026-02-05 Qianyi Xu , Gousia Habib , Feng Wu , Yanrui Du , Zhihui Chen , Swapnil Mishra , Dilruk Perera , Mengling Feng

Background: Large language models (LLMs) show promise in medicine, but their deployment in hospitals is limited by restricted access to electronic health record (EHR) systems. The Model Context Protocol (MCP) enables integration between…

Artificial Intelligence · Computer Science 2025-09-22 Kanato Masayoshi , Masahiro Hashimoto , Ryoichi Yokoyama , Naoki Toda , Yoshifumi Uwamino , Shogo Fukuda , Ho Namkoong , Masahiro Jinzaki

Accessing longitudinal multimodal Electronic Healthcare Records (EHRs) is challenging due to privacy concerns, which hinders the use of ML for healthcare applications. Synthetic EHRs generation bypasses the need to share sensitive real…

Computation and Language · Computer Science 2022-11-04 Zifeng Wang , Jimeng Sun

Electronic health records (EHRs) contain vast amounts of complex data, but harmonizing and processing this information remains a challenging and costly task requiring significant clinical expertise. While large language models (LLMs) have…

Computation and Language · Computer Science 2024-07-02 João Matos , Jack Gallifant , Jian Pei , A. Ian Wong

Clinical forecasting based on electronic medical records (EMR) can uncover the temporal correlations between patients' conditions and outcomes from sequences of longitudinal clinical measurements. In this work, we propose an…

Machine Learning · Computer Science 2019-12-05 Yuan Xue , Denny Zhou , Nan Du , Andrew Dai , Zhen Xu , Kun Zhang , Claire Cui

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio
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