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Processing histopathological Whole Slide Images (WSI) leads to massive storage requirements for clinics worldwide. Even after lossy image compression during image acquisition, additional lossy compression is frequently possible without…

Unsupervised sentence representation learning remains a critical challenge in modern natural language processing (NLP) research. Recently, contrastive learning techniques have achieved significant success in addressing this issue by…

Computation and Language · Computer Science 2024-11-20 Wenxiao Liu , Zihong Yang , Chaozhuo Li , Zijin Hong , Jianfeng Ma , Zhiquan Liu , Litian Zhang , Feiran Huang

Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary insights. However, aligning different stains at the cell level…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jun Jiang , Raymond Moore , Brenna Novotny , Leo Liu , Zachary Fogarty , Ray Guo , Markovic Svetomir , Chen Wang

Previous studies have shown the great potential of capsule networks for the spatial contextual feature extraction from {hyperspectral images (HSIs)}. However, the sampling locations of the convolutional kernels of capsules are fixed and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Jinping Wang , Xiaojun Tan , Jianhuang Lai , Jun Li , Canqun Xiang

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Understanding the way cells communicate, co-locate, and interrelate is essential to furthering our understanding of how the body functions. H&E is widely available, however, cell subtyping often requires expert knowledge and the use of…

Contrastive learning (CL) has become a dominant paradigm for self-supervised hypergraph learning, enabling effective training without costly labels. However, node entities in real-world hypergraphs are often associated with rich textual…

Machine Learning · Computer Science 2026-05-26 Mengting Pan , Fan Li , Chen Chen , Xiaoyang Wang , Wenjie Zhang

In whole slide imaging, commonly used staining techniques based on hematoxylin and eosin (H&E) and immunohistochemistry (IHC) stains accentuate different aspects of the tissue landscape. In the case of detecting metastases, IHC provides a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Joseph Boyd , Irène Villa , Marie-Christine Mathieu , Eric Deutsch , Nikos Paragios , Maria Vakalopoulou , Stergios Christodoulidis

With the advent of digital scanners and deep learning, diagnostic operations may move from a microscope to a desktop. Hematoxylin and Eosin (H&E) staining is one of the most frequently used stains for disease analysis, diagnosis, and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Shikha Dubey , Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

Histopathological diagnoses of tumors in tissue biopsy after Hematoxylin and Eosin (H&E) staining is the gold standard for oncology care. H&E staining is slow and uses dyes, reagents and precious tissue samples that cannot be reused.…

Whole-Slide Images (WSIs) are widely used for estimating the prognosis of cancer patients. Current studies generally follow a cancer-specific learning paradigm. However, the available training samples for one cancer type are usually scarce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Pei Liu , Xiangxiang Zeng , Tengfei Ma , Yucheng Xing , Xuanbai Ren , Yiping Liu

Hematoxylin and Eosin (H&E) stained Whole Slide Images (WSIs) are utilized for biopsy visualization-based diagnostic and prognostic assessment of diseases. Variation in the H&E staining process across different lab sites can lead to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-24 Aman Shrivastava , Will Adorno , Yash Sharma , Lubaina Ehsan , S. Asad Ali , Sean R. Moore , Beatrice C. Amadi , Paul Kelly , Sana Syed , Donald E. Brown

Multiple instance learning (MIL) is the dominant framework for whole-slide image analysis in computational pathology, typically combining a frozen patch encoder, a projection layer, and a slide-level aggregator. While encoders and…

Quantitative Methods · Quantitative Biology 2026-05-19 Yucheng Xing , Pei Liu , Jingying Ma , Ruping Hong , Jiangdong Qiu , Tianyu Liu , Kai He , Ling Huang , Mengling Feng

Learning-based multi-view stereo (MVS) has gained fine reconstructions on popular datasets. However, supervised learning methods require ground truth for training, which is hard to be collected, especially for the large-scale datasets.…

Computer Vision and Pattern Recognition · Computer Science 2022-03-07 Haonan Dong , Jian Yao

Learning discriminative image representations plays a vital role in long-tailed image classification because it can ease the classifier learning in imbalanced cases. Given the promising performance contrastive learning has shown recently in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Peng Wang , Kai Han , Xiu-Shen Wei , Lei Zhang , Lei Wang

The global reach of social media has amplified the spread of hateful content, including implicit sexism, which is often overlooked by conventional detection methods. In this work, we introduce an Adaptive Supervised Contrastive lEarning…

Computation and Language · Computer Science 2025-07-09 Mohammad Zia Ur Rehman , Aditya Shah , Nagendra Kumar

Recent advances in self-supervised learning (SSL) have largely closed the gap with supervised ImageNet pretraining. Despite their success these methods have been primarily applied to unlabeled ImageNet images, and show marginal gains when…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Ramprasaath R. Selvaraju , Karan Desai , Justin Johnson , Nikhil Naik

Significance: Histopathological analysis of tissues is an essential tool for grading, staging, diagnosing and resecting cancers and other malignancies. Current histopathological techniques require substantial sample processing prior to…

Medical Physics · Physics 2021-07-14 Benjamin Ecclestone , Deepak Dinakaran , Parsin Haji Reza

Image classification is hindered by subtle inter-class differences and substantial intra-class variations, which limit the effectiveness of existing contrastive learning methods. Supervised contrastive approaches based on the InfoNCE loss…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Bin Wang , Fadi Dornaika

Accurate cell counting in immunohistochemistry (IHC) images is critical for quantifying protein expression and aiding cancer diagnosis. However, the task remains challenging due to the chromogen overlap, variable biomarker staining, and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zuqi Huang , Mengxin Tian , Huan Liu , Wentao Li , Baobao Liang , Jie Wu , Fang Yan , Zhaoqing Tang , Zhongyu Li
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