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We introduce a machine learning-based method for fully automated diagnosis of sickle cell disease of poor-quality unstained images of a mobile microscope. Our method is capable of distinguishing between diseased, trait (carrier), and normal…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Sahar A. Nasser , Debjani Paul , Suyash P. Awate

Accurate and robust classification of diseases is important for proper diagnosis and treatment. However, medical datasets often face challenges related to limited sample sizes and inherent imbalanced distributions, due to difficulties in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Shuhan Li , Yi Lin , Hao Chen , Kwang-Ting Cheng

Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…

Quantitative Methods · Quantitative Biology 2024-06-13 Erin Craig , Timothy Keyes , Jolanda Sarno , Maxim Zaslavsky , Garry Nolan , Kara Davis , Trevor Hastie , Robert Tibshirani

It has become routine in neuroscience studies to measure brain networks for different individuals using neuroimaging. These networks are typically expressed as adjacency matrices, with each cell containing a summary of connectivity between…

Methodology · Statistics 2022-06-30 Pritam Dey , Zhengwu Zhang , David B. Dunson

Improving the retrieval relevance on noisy datasets is an emerging need for the curation of a large-scale clean dataset in the medical domain. While existing methods can be applied for class-wise retrieval (aka. inter-class), they cannot…

Computer Vision and Pattern Recognition · Computer Science 2022-04-08 Xiaoyuan Guo , Jiali Duan , Saptarshi Purkayastha , Hari Trivedi , Judy Wawira Gichoya , Imon Banerjee

Medical image classification is a challenging task due to the scarcity of labeled samples and class imbalance caused by the high variance in disease prevalence. Semi-supervised learning (SSL) methods can mitigate these challenges by…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Md Junaid Mahmood , Pranaw Raj , Divyansh Agarwal , Suruchi Kumari , Pravendra Singh

Label-free imaging has gained broad interest because of its potential to omit elaborate staining procedures which is especially relevant for in vivo use. Label-free multiphoton microscopy (MPM), for instance, exploits two-photon excitation…

Traditional anomaly detection methods focus on detecting inter-class variations while medical image novelty identification is inherently an intra-class detection problem. For example, a machine learning model trained with normal chest X-ray…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Xiaoyuan Guo , Judy Wawira Gichoya , Saptarshi Purkayastha , Imon Banerjee

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Deep learning approaches are successful in a wide range of AI problems and in particular for visual recognition tasks. However, there are still open problems among which is the capacity to handle streams of visual information and the…

Machine Learning · Computer Science 2022-02-02 Umang Aggarwal , Adrian Popescu , Eden Belouadah , Céline Hudelot

Deep learning has shown promising results in medical image analysis, however, the lack of very large annotated datasets confines its full potential. Although transfer learning with ImageNet pre-trained classification models can alleviate…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Ken C. L. Wong , Tanveer Syeda-Mahmood , Mehdi Moradi

We focus on the real-world problem of training accurate deep models for image classification of a small number of rare categories. In these scenarios, almost all images belong to the background category in the dataset (>95% of the dataset…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Ravi Teja Mullapudi , Fait Poms , William R. Mark , Deva Ramanan , Kayvon Fatahalian

Various technologies, including computer vision models, are employed for the automatic monitoring of manual assembly processes in production. These models detect and classify events such as the presence of components in an assembly area or…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Anton Sergeev , Victor Minchenkov , Aleksei Soldatov , Vasiliy Kakurin , Yaroslav Mazikov

In this study, we systematically investigate the impact of class imbalance on classification performance of convolutional neural networks (CNNs) and compare frequently used methods to address the issue. Class imbalance is a common problem…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Mateusz Buda , Atsuto Maki , Maciej A. Mazurowski

We propose a novel unsupervised out-of-distribution detection method for medical images based on implicit fields image representations. In our approach, an auto-decoder feed-forward neural network learns the distribution of healthy images…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Sergio Naval Marimont , Giacomo Tarroni

The collected data from industrial machines are often imbalanced, which poses a negative effect on learning algorithms. However, this problem becomes more challenging for a mixed type of data or while there is overlapping between classes.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-10 Masoumeh Zareapoor , Pourya Shamsolmoali , Jie Yang

Solving the classification problem, unbalanced number of dataset among the classes often causes performance degradation. Especially when some classes dominate the other classes with its large number of datasets, trained model shows low…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Dohyeun Kim , Tae Joon Jun , Daeyoung Kim , Youngsub Eom

User activities generate a significant number of poor-quality or irrelevant images and data vectors that cannot be processed in the main data processing pipeline or included in the training dataset. Such samples can be found with manual…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Garnik Vareldzhan , Kirill Yurkov , Konstantin Ushenin

Learning from imbalanced data is one of the most significant challenges in real-world classification tasks. In such cases, neural networks performance is substantially impaired due to preference towards the majority class. Existing…

Machine Learning · Computer Science 2022-11-13 Bronislav Yasinnik , Moshe Salhov , Ofir Lindenbaum , Amir Averbuch

Medical image classification plays an increasingly vital role in identifying various diseases by classifying medical images, such as X-rays, MRIs and CT scans, into different categories based on their features. In recent years, deep…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Zeeshan Ahmad , Shudi Bao , Meng Chen
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