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Deep learning based models have had great success in object detection, but the state of the art models have not yet been widely applied to biological image data. We apply for the first time an object detection model previously used on…

The challenge of imbalanced data is prominent in medical image classification. This challenge arises when there is a significant disparity in the number of images belonging to a particular class, such as the presence or absence of a…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Sina Jahromi , Farshid Hajati , Alireza Rezaee , Javaher Nourian

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

In this work, we propose a two-stage autoencoder based compressor-decompressor framework for compressing malaria RBC cell image patches. We know that the medical images used for disease diagnosis are around multiple gigabytes size, which is…

Image and Video Processing · Electrical Eng. & Systems 2021-08-25 Dipti Mishra , Satish Kumar Singh , Rajat Kumar Singh

We propose performing imbalanced classification by regrouping majority classes into small classes so that we turn the problem into balanced multiclass classification. This new idea is dramatically different from popular loss reweighting and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-28 Le Peng , Yash Travadi , Rui Zhang , Ying Cui , Ju Sun

In medical image processing, accurate diagnosis is of paramount importance. Leveraging machine learning techniques, particularly top-rank learning, shows significant promise by focusing on the most crucial instances. However, challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Xiaotong Ji , Ryoma Bise , Seiichi Uchida

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Highly imbalanced datasets are ubiquitous in medical image classification problems. In such problems, it is often the case that rare classes associated to less prevalent diseases are severely under-represented in labeled databases,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Adrian Galdran , Gustavo Carneiro , Miguel A. González Ballester

Anomaly detection aims at identifying data points that show systematic deviations from the majority of data in an unlabeled dataset. A common assumption is that clean training data (free of anomalies) is available, which is often violated…

Machine Learning · Computer Science 2022-07-20 Chen Qiu , Aodong Li , Marius Kloft , Maja Rudolph , Stephan Mandt

One challenging property lurking in medical datasets is the imbalanced data distribution, where the frequency of the samples between the different classes is not balanced. Training a model on an imbalanced dataset can introduce unique…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Ashkan Khakzar , Yawei Li , Yang Zhang , Mirac Sanisoglu , Seong Tae Kim , Mina Rezaei , Bernd Bischl , Nassir Navab

Deep learning methods can classify various unstructured data such as images, language, and voice as input data. As the task of classifying anomalies becomes more important in the real world, various methods exist for classifying using deep…

Computer Vision and Pattern Recognition · Computer Science 2022-01-06 UJu Gim , YeongHyeon Park

Recent advances in deep learning led to novel generative modeling techniques that achieve unprecedented quality in generated samples and performance in learning complex distributions in imaging data. These new models in medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Xiaoran Chen , Nick Pawlowski , Martin Rajchl , Ben Glocker , Ender Konukoglu

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

Malaria is a deadly disease which claims the lives of hundreds of thousands of people every year. Computational methods have been proven to be useful in the medical industry by providing effective means of classification of diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Rishabh Malhotra , Dhron Joshi , Ku Young Shin

One way to extract patterns from clinical records is to consider each patient record as a bag with various number of instances in the form of symptoms. Medical diagnosis is to discover informative ones first and then map them to one or more…

Machine Learning · Computer Science 2019-04-10 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Due to the intractability of characterizing everything that looks unlike the normal data, anomaly detection (AD) is traditionally treated as an unsupervised problem utilizing only normal samples. However, it has recently been found that…

Computer Vision and Pattern Recognition · Computer Science 2023-01-29 Philipp Liznerski , Lukas Ruff , Robert A. Vandermeulen , Billy Joe Franks , Klaus-Robert Müller , Marius Kloft

Malaria remains a prevalent health concern in regions with tropical and subtropical climates. The cause of malaria is the Plasmodium parasite, which is transmitted through the bites of infected female Anopheles mosquitoes. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Md. Ismiel Hossen Abir , Awolad Hossain

Recently, deep learning models have achieved great success in computer vision applications, relying on large-scale class-balanced datasets. However, imbalanced class distributions still limit the wide applicability of these models due to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-05 Yechan Kim , Younkwan Lee , Moongu Jeon

Malaria, a mosquito-borne disease caused by a parasite, kills over 1 million people globally each year. People, if left untreated, may develop severe complications, leading to death. Effective and accurate diagnosis is important for the…

Image and Video Processing · Electrical Eng. & Systems 2020-09-02 Alexander Tao , Boran Han

In many real-world pattern recognition scenarios, such as in medical applications, the corresponding classification tasks can be of an imbalanced nature. In the current study, we focus on binary, imbalanced classification tasks, i.e.~binary…

Machine Learning · Computer Science 2020-12-01 Peter Bellmann , Heinke Hihn , Daniel A. Braun , Friedhelm Schwenker