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Physiologically Based Pharmacokinetic (PBPK) modeling is a key tool in drug development for predicting drug concentration dynamics across organs. Traditional PBPK approaches rely on ordinary differential equations with simplifying…

Machine Learning · Computer Science 2026-01-06 Su Liu , Xin Hu , Shurong Wen , Chengyi Chen , Jiaqi Liu , Lanruo Wang , Jiexi Xu

Masked generative models (MGMs) can generate tokens in parallel and in any order, unlike autoregressive models (ARMs), which decode one token at a time, left-to-right. However, MGMs process the full-length sequence at every sampling step,…

Machine Learning · Computer Science 2026-02-18 Justin Deschenaux , Lan Tran , Caglar Gulcehre

Different types of graphene-related materials (GRM) are industrially available and have been exploited for thermal conductivity enhancement in polymers. These include materials with very different features, in terms of thickness, lateral…

Applied Physics · Physics 2021-01-25 Samuele Colonna , Daniele Battegazzore , Matteo Eleuteri , Rossella Arrigo , Alberto Fina

While physics conveys knowledge of nature built from an interplay between observations and theory, it has been considered less importantly in deep neural networks. Especially, there are few works leveraging physics behaviors when the…

Machine Learning · Computer Science 2019-02-12 Sungyong Seo , Yan Liu

From AlexNet to Inception, autoencoders to diffusion models, the development of novel and powerful deep learning models and learning algorithms has proceeded at breakneck speeds. In part, we believe that rapid iteration of model…

Computational Engineering, Finance, and Science · Computer Science 2022-11-17 Shehtab Zaman , Ethan Ferguson , Cecile Pereira , Denis Akhiyarov , Mauricio Araya-Polo , Kenneth Chiu

Recently, machine learning (ML) has been used to address the computational cost that has been limiting ab initio molecular dynamics (AIMD). Here, we present GNNFF, a graph neural network framework to directly predict atomic forces from…

Synthetic polymers are versatile and widely used materials. Similar to small organic molecules, a large chemical space of such materials is hypothetically accessible. Computational property prediction and virtual screening can accelerate…

Machine Learning · Computer Science 2022-10-13 Matteo Aldeghi , Connor W. Coley

The mechanical response of interpenetrating phase composites (IPCs) with stochastic spinodal topologies is investigated experimentally and numerically. Model polymeric systems are fabricated by Polyjet multi-material printing, with the…

Applied Physics · Physics 2021-02-16 Yunfei Zhang , Meng-Ting Hsieh , Lorenzo Valdevit

We present a framework for the multiscale modeling of finite strain magneto-elasticity based on physics-augmented neural networks (NNs). By using a set of problem specific invariants as input, an energy functional as the output and by…

Computational Engineering, Finance, and Science · Computer Science 2023-09-01 Karl A. Kalina , Philipp Gebhart , Jörg Brummund , Lennart Linden , WaiChing Sun , Markus Kästner

A coarse-grained model is developed to allow large-scale molecular dynamics (MD) simulations of a branched polyetherimide derived from two backbone monomers [4,4'-bisphenol A dianhydride (BPADA) and m-phenylenediamine (MPD)], a chain…

Materials Science · Physics 2021-01-15 Chengyuan Wen , Roy Odle , Shengfeng Cheng

We study the structural and dynamical mechanisms of reinforcement of a polymer nanocomposite (PNC) via coarse-grained molecular dynamics simulations. In a regime of strong polymer-filler interactions, the stress at failure of the PNC is…

Soft Condensed Matter · Physics 2012-04-27 Kutvonen Aki , Rossi Giulia , Ala-Nissila Tapio

Woven fabrics play an essential role in everyday textiles for clothing/sportswear, water filtration, and retaining walls, to reinforcements in stiff composites for lightweight structures like aerospace, sporting, automotive, and marine…

Applied Physics · Physics 2023-11-27 Haotian Feng , Sabarinathan P Subramaniyan , Hridyesh Tewani , Pavana Prabhakar

Polymers play a crucial role in the development of engineering materials, with applications ranging from mechanical to biomedical fields. However, the limited polymerization processes constrain the variety of organic building blocks that…

Soft Condensed Matter · Physics 2024-12-13 Debasish Mohanty , V Shreyas , Akshaya Palai , Bharath Ramsundar

Recent advances in applying Graph Neural Networks (GNNs) to molecular science have showcased the power of learning three-dimensional (3D) structure representations with GNNs. However, most existing GNNs suffer from the limitations of…

Biomolecules · Quantitative Biology 2023-11-21 Shuo Zhang , Yang Liu , Lei Xie

A coarse grained model for flexible polymers end-grafted to repulsive spherical nanoparticles is studied for various chain lengths and grafting densities under good solvent conditions, by Molecular Dynamics methods and density functional…

Soft Condensed Matter · Physics 2015-05-18 Federica Lo Verso , Sergei A. Egorov , Andrey Milchev , Kurt Binder

Graph neural networks (GNNs) naturally align with sparse operators and unstructured discretizations, making them a promising paradigm for physics-informed machine learning in computational mechanics. Motivated by discrete physics losses and…

Machine Learning · Computer Science 2026-02-10 Jianchuan Yang , Xi Chen , Jidong Zhao

Machine learning (ML) methods have gained increasing popularity in exploring and developing new materials. More specifically, graph neural network (GNN) has been applied in predicting material properties. In this work, we develop a novel…

Computational Physics · Physics 2020-08-18 Steph-Yves Louis , Yong Zhao , Alireza Nasiri , Xiran Wong , Yuqi Song , Fei Liu , Jianjun Hu

Vertical graphene nanosheets (VGNs) are the material of choice for next-generation electronic device applications. The growing demand for flexible devices in electronic industry brings in restriction on growth temperature of the material of…

Materials Science · Physics 2022-02-02 Gopinath Sahoo , Subrata Ghosh , S. R. Polaki , Tom Mathews , M. Kamruddin

Physical systems are commonly represented as a combination of particles, the individual dynamics of which govern the system dynamics. However, traditional approaches require the knowledge of several abstract quantities such as the energy or…

Machine Learning · Computer Science 2022-09-07 Ravinder Bhattoo , Sayan Ranu , N. M. Anoop Krishnan

Production forecast based on historical data provides essential value for developing hydrocarbon resources. Classic history matching workflow is often computationally intense and geometry-dependent. Analytical data-driven models like…

Machine Learning · Computer Science 2022-09-27 Wendi Liu , Michael J. Pyrcz