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In this work we study the stability properties of the equilibrium points of deterministic epidemic models with nonconstant population size. Models with nonconstant population have been studied in the past only in particular cases, two of…

Optimization and Control · Mathematics 2022-02-25 Florin Avram , Rim Adenane , Lasko Basnarkov , Gianluca Bianchin , Dan Goreac , Andrei Halanay

We present an epidemiological compartment model, SAIR(S), that explicitly captures the dynamics of asymptomatic infected individuals in an epidemic spread process. We first present a group model and then discuss networked versions. We…

Populations and Evolution · Quantitative Biology 2021-03-23 Xiaoqi Bi , Carolyn L. Beck

We consider the $SEIRS$ epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. Within a compartmental realization of this…

Populations and Evolution · Quantitative Biology 2021-12-07 Jaroslav Ilnytskyi , Taras Patsahan

In this work, we use a new approach to study the spread of an infectious disease. Indeed, we study a SIR epidemic model with variable infectivity, where the individuals are distributed over a compact subset $D$ of $\R^d$. We define…

Probability · Mathematics 2025-11-18 Armand Kanga , Etienne Pardoux

Recent years have seen a large amount of interest in epidemics on networks as a way of representing the complex structure of contacts capable of spreading infections through the modern human population. The configuration model is a popular…

Populations and Evolution · Quantitative Biology 2017-01-23 Frank Ball , Thomas House

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

Optimization and Control · Mathematics 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

Epidemic models are used to analyze the progression or outcome of an epidemic under different control policies like vaccinations, quarantines, lockdowns, use of face-masks, pharmaceutical interventions, etc. When these models accurately…

Quantitative Methods · Quantitative Biology 2022-04-19 Carlos Hernandez-Suarez , Osval Montsinos Lopez , Ramon Solano-Barajas

We tackle limitations of ordinary differential equation-driven Susceptible-Infections-Removed (SIR) models and their extensions that have recently be employed for epidemic nowcasting and forecasting. In particular, we deal with challenges…

Computation · Statistics 2026-02-10 Angelos Alexopoulos , Paul Birrell , Daniela De Angelis

In this paper, we develop a robust economic model predictive controller for the containment of stochastic Susceptible-Exposed-Infected-Vigilant (SEIV) epidemic processes which drives the process to extinction quickly, while minimizing the…

Optimization and Control · Mathematics 2019-05-14 Nicholas J. Watkins , Cameron Nowzari , George J. Pappas

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Applications · Statistics 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

We develop a novel approach towards causal inference. Rather than structural equations over a causal graph, we learn stochastic differential equations (SDEs) whose stationary densities model a system's behavior under interventions. These…

Machine Learning · Computer Science 2024-03-19 Lars Lorch , Andreas Krause , Bernhard Schölkopf

We develop a new perturbation method for studying quasi-neutral competition in a broad class of stochastic competition models, and apply it to the analysis of fixation of competing strains in two epidemic models. The first model is a…

Statistical Mechanics · Physics 2016-10-06 Oleg Kogan , Michael Khasin , Baruch Meerson , David Schneider , Christopher R. Myers

The COVID-19 pandemic highlighted the need to improve the modeling, estimation, and prediction of how infectious diseases spread. SEIR-like models have been particularly successful in providing accurate short-term predictions. This study…

Populations and Evolution · Quantitative Biology 2024-12-31 Jorge P. Zubelli , Jennifer Loria , Vinicius V. L. Albani

A pandemic caused by a new coronavirus (COVID-19) has spread worldwide, inducing an epidemic still active in Argentina. In this chapter, we present a case study using an SEIR (Susceptible-Exposed-Infected-Recovered) diffusion model of…

Populations and Evolution · Quantitative Biology 2021-04-08 Juan Santos , José Carcione , Gabriela Savioli , Patricia Gauzellino

We propose a compartmental model for epidemiology wherein the population is split into groups with either comply or refuse to comply with protocols designed to slow the spread of a disease. Parallel to the disease spread, we assume that…

Dynamical Systems · Mathematics 2025-11-27 Christian Parkinson , Weinan Wang

Population heterogeneity is a key factor in epidemic dynamics, influencing both transmission and final epidemic size. While heterogeneity is often modelled through age structure, spatial location, or contact patterns, differences in host…

Populations and Evolution · Quantitative Biology 2026-01-26 Tamás Tekeli , Andrea Pugliese , Cinzia Soresina

We develop an extension of the Susceptible-Infected-Recovery (SIR) model to account for spatial variations in population as well as infection and recovery parameters. The equations are derived by taking the continuum limit of discrete…

Mesoscale and Nanoscale Physics · Physics 2025-02-04 Abhimanyu Ghosh

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

In this paper, we consider a discrete-time stochastic SIR model, where the transmission rate and the true number of infectious individuals are random and unobservable. An advantage of this model is that it permits us to account for random…

Physics and Society · Physics 2024-01-30 Katia Colaneri , Camilla Damian , Rüdiger Frey

Petri Nets are an increasingly used modeling framework for the spread of disease across populations or within an individual. For example, the Susceptible-Infectious-Recovered (SIR) compartment model is foundational for population…

Other Quantitative Biology · Quantitative Biology 2025-07-02 Trevor Reckell , Bright Kwaku Manu , Beckett Sterner , Petar Jevtić , Reggie Davidrajuh