Related papers: A Multi-Scale Simulation of Retinal Physiology
Biomedical optical imaging has a possibility of a comprehensive diagnosis of thyroid cancer in conjunction with ultrasound imaging. For improvement of the optical imaging, this study develops a higher order scheme for solving the…
Nonlinear quantum photonics serves as a cornerstone in photonic quantum technologies, such as universal quantum computing and quantum communications. The emergence of integrated photonics platform not only offers the advantage of…
Advances in silicon photonics technology have enabled the field of neuromorphic photonics, where analog neuron-like processing elements are implemented in silicon photonics technology. Accurate and scalable simulation tools for photonic…
We present a computational approach for solving reaction-diffusion equations on evolving surfaces which have been obtained from cell image data. It is based on finite element spaces defined on surface triangulations extracted from time…
Effective and accurate in-vivo diagnosis of retinal pathologies requires high performance imaging devices, combining a large field of view and the ability to discriminate the ballistic signal from the diffuse background in order to provide…
Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge…
The spatial distribution of neuronal cells is an important requirement for achieving proper neuronal function in several parts of the nervous system of most animals. For instance, specific distribution of photoreceptors and related neuronal…
The optical cross sections of plasmonic nanoparticles are intricately linked to the morphology of the particle. If this connection can be made accurately enough, it would become possible to determine a particles shape solely from its…
In these lectures I will review the approach to glasses based on the replica formalism. Many of the physical ideas are very similar to those of older approaches. The replica approach has the advantage of describing in an unified setting…
The in vivo observation of the human retina at the cellular level is crucial to detect lesions before irreversible visual loss occurs, to follow the time course of retinal diseases and to evaluate and monitor the early effects of…
We develop a comprehensive approach to simulate the deformation of mirrors and lenses due to thermal and mechanical stresses that couples efficiently to photon-based optics simulations. This expands upon previous work where we demonstrated…
Like many other biological processes, calcium dynamics in neurons containing an endoplasmic reticulum are governed by diffusion-reaction equations on interface-separated domains. Interface conditions are typically described by systems of…
Modelling of photonic devices traditionally involves solving the equations of light-matter interaction and light propagation, and it is restrained by their applicability. Here we demonstrate an alternative modelling methodology by creating…
Accurate detection and segmentation of cone cells in the retina are essential for diagnosing and managing retinal diseases. In this study, we used advanced imaging techniques, including confocal and non-confocal split detector images from…
Purpose: To demonstrate that retinal microvasculature per se is a reliable biomarker for Diabetic Retinopathy (DR) and, by extension, cardiovascular diseases. Methods: Deep Learning Convolutional Neural Networks (CNN) applied to color…
The concept of a cell$'$s receptive field is a bedrock in systems neuroscience, and the classical static description of the receptive field has had enormous success in explaining the fundamental mechanisms underlying visual processing.…
In this article, we follow the trajectory of a photon in the human cornea. Prior to experimental evidence of the cornea's gradient refractive index (GRIN) nature, schematic eye models used a constant or average as the corneal refractive…
This paper covers the design and programming of a hybrid (digital/analog) neural network to function as an artificial retina with the ability to perform a spatial discrete cosine transform. We describe the structure of the circuit, which…
Using molecular simulation to aid in the analysis of neutron reflectometry measurements is commonplace. However, reflectometry is a tool to probe large-scale structures, and therefore the use of all-atom simulation may be irrelevant. This…
Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…