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Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake

Purpose: Interpreting chest radiographs (CXR) remains challenging due to the ambiguity of overlapping structures such as the lungs, heart, and bones. To address this issue, we propose a novel method for extracting fine-grained anatomical…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Constantin Seibold , Alexander Jaus , Matthias A. Fink , Moon Kim , Simon Reiß , Ken Herrmann , Jens Kleesiek , Rainer Stiefelhagen

In computer-assisted surgery, automatically recognizing anatomical organs is crucial for understanding the surgical scene and providing intraoperative assistance. While machine learning models can identify such structures, their deployment…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Danush Kumar Venkatesh , Dominik Rivoir , Micha Pfeiffer , Fiona Kolbinger , Stefanie Speidel

Accurate and generalizable object segmentation in ultrasound imaging remains a significant challenge due to anatomical variability, diverse imaging protocols, and limited annotated data. In this study, we propose a prompt-driven…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Hamza Rasaee , Taha Koleilat , Hassan Rivaz

In clinical practice, regions of interest in medical imaging often need to be identified through a process of precise image segmentation. The quality of this image segmentation step critically affects the subsequent clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-23 João B. S. Carvalho , João A. Santinha , Đorđe Miladinović , Joachim M. Buhmann

Performing coarse-to-fine abdominal multi-organ segmentation facilitates to extract high-resolution segmentation minimizing the lost of spatial contextual information. However, current coarse-to-refine approaches require a significant…

Image and Video Processing · Electrical Eng. & Systems 2020-12-25 Ho Hin Lee , Yucheng Tang , Shunxing Bao , Richard G. Abramson , Yuankai Huo , Bennett A. Landman

Within this thesis we propose a platform for combining Augmented Reality (AR) hardware with machine learning in a user-oriented pipeline, offering to the medical staff an intuitive 3D visualization of volumetric Computed Tomography (CT) and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Lucian Trestioreanu

Numerical investigation of the interaction of electromagnetic fields with eukaryotic cells requires specifically adapted computer models. Virtual microdosimetry, used to investigate exposure, requires volumetric cell models, which are…

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Simon Reiß , Constantin Seibold , Alexander Freytag , Erik Rodner , Rainer Stiefelhagen

State-of-the-art methods for semantic segmentation of images involve computationally intensive neural network architectures. Most of these methods are not adaptable to high-resolution image segmentation due to memory and other computational…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Siddharth Saravanan , Aditya Challa , Sravan Danda

Purpose: Bone metastasis have a major impact on the quality of life of patients and they are diverse in terms of size and location, making their segmentation complex. Manual segmentation is time-consuming, and expert segmentations are…

Image and Video Processing · Electrical Eng. & Systems 2024-09-18 Emile Saillard , Aurélie Levillain , David Mitton , Jean-Baptiste Pialat , Cyrille Confavreux , Hélène Follet , Thomas Grenier

Segmentation, or the outlining of objects within images, is a critical step in the measurement and analysis of cells within microscopy images. While improvements continue to be made in tools that rely on classical methods for segmentation,…

Quantitative Methods · Quantitative Biology 2024-03-15 Nodar Gogoberidze , Beth A. Cimini

The present paper develops a general methodology for the morphological segmentation of hyperspectral images, i.e., with an important number of channels. This approach, based on watershed, is composed of a spectral classification to obtain…

Image and Video Processing · Electrical Eng. & Systems 2020-10-05 Guillaume Noyel , Jesus Angulo , Dominique Jeulin

Semantic tool segmentation in surgical videos is important for surgical scene understanding and computer-assisted interventions as well as for the development of robotic automation. The problem is challenging because different illumination…

Computer Vision and Pattern Recognition · Computer Science 2020-07-28 Emanuele Colleoni , Philip Edwards , Danail Stoyanov

Annotating multiple organs in 3D medical images is time-consuming and costly. Meanwhile, there exist many single-organ datasets with one specific organ annotated. This paper investigates how to learn a multi-organ segmentation model…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Shixiang Feng , Yuhang Zhou , Xiaoman Zhang , Ya Zhang , Yanfeng Wang

Accurate and efficient catheter segmentation in 3D ultrasound (US) is essential for cardiac intervention. Currently, the state-of-the-art segmentation algorithms are based on convolutional neural networks (CNNs), which achieved remarkable…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Hongxu Yang , Caifeng Shan , Alexander F. Kolen , Peter H. N. de With

Purpose: This paper describes a new method to apply deep-learning algorithms for automatic segmentation of radiosensitive organs from 3D tomographic CT images before computing organ doses using a GPU-based Monte Carlo code. Methods: A deep…

Medical Physics · Physics 2020-09-09 Zhao Peng , Xi Fang , Pingkun Yan , Hongming Shan , Tianyu Liu , Xi Pei , Ge Wang , Bob Liu , Mannudeep K. Kalra , X. George Xu

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

The ability to dynamically extend a model to new data and classes is critical for multiple organ and tumor segmentation. However, due to privacy regulations, accessing previous data and annotations can be problematic in the medical domain.…

Image and Video Processing · Electrical Eng. & Systems 2023-07-24 Yixiao Zhang , Xinyi Li , Huimiao Chen , Alan Yuille , Yaoyao Liu , Zongwei Zhou