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Training machine learning models to segment tumors and other anomalies in medical images is an important step for developing diagnostic tools but generally requires manually annotated ground truth segmentations, which necessitates…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Jay J. Yoo , Khashayar Namdar , Farzad Khalvati

Weakly-supervised diffusion models (DMs) in anomaly segmentation, leveraging image-level labels, have attracted significant attention for their superior performance compared to unsupervised methods. It eliminates the need for pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Yiming Che , Fazle Rafsani , Jay Shah , Md Mahfuzur Rahman Siddiquee , Teresa Wu

Segmentation of brain structures from MRI is crucial for evaluating brain morphology, yet existing CNN and transformer-based methods struggle to delineate complex structures accurately. While current diffusion models have shown promise in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qilong Xing , Zikai Song , Yuteng Ye , Yuke Chen , Youjia Zhang , Na Feng , Junqing Yu , Wei Yang

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas

Anomaly inspection plays an important role in industrial manufacture. Existing anomaly inspection methods are limited in their performance due to insufficient anomaly data. Although anomaly generation methods have been proposed to augment…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Teng Hu , Jiangning Zhang , Ran Yi , Yuzhen Du , Xu Chen , Liang Liu , Yabiao Wang , Chengjie Wang

Purpose: Lesion segmentation in medical imaging is key to evaluating treatment response. We have recently shown that reinforcement learning can be applied to radiological images for lesion localization. Furthermore, we demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Joseph Stember , Hrithwik Shalu

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to detect outliers either in…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Changhee Han , Leonardo Rundo , Kohei Murao , Tomoyuki Noguchi , Yuki Shimahara , Zoltan Adam Milacski , Saori Koshino , Evis Sala , Hideki Nakayama , Shinichi Satoh

Multi-center neuroimaging studies face technical variability due to batch differences across sites, which potentially hinders data aggregation and impacts study reliability.Recent efforts in neuroimaging harmonization have aimed to minimize…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Haoyu Lan , Bino A. Varghese , Nasim Sheikh-Bahaei , Farshid Sepehrband , Arthur W Toga , Jeiran Choupan

This paper is a contribution to the "BraTS 2023 Local Synthesis of Healthy Brain Tissue via Inpainting Challenge". The task of this challenge is to transform tumor tissue into healthy tissue in brain magnetic resonance (MR) images. This…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Alicia Durrer , Philippe C. Cattin , Julia Wolleb

Deep learning models usually require sufficient training data to achieve high accuracy, but obtaining labeled data can be time-consuming and labor-intensive. Here we introduce a template-based training method to train a 3D U-Net model from…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Fang-Cheng Yeh

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Reconstruction-based methods have been commonly used for unsupervised anomaly detection, in which a normal image is reconstructed and compared with the given test image to detect and locate anomalies. Recently, diffusion models have shown…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Di Wu , Shicai Fan , Xue Zhou , Li Yu , Yuzhong Deng , Jianxiao Zou , Baihong Lin

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Quantitative Susceptibility Mapping (QSM) dipole inversion is an ill-posed inverse problem for quantifying magnetic susceptibility distributions from MRI tissue phases. While supervised deep learning methods have shown success in specific…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Zhuang Xiong , Wei Jiang , Yang Gao , Feng Liu , Hongfu Sun

Diffuse gliomas are malignant brain tumors that grow widespread through the brain. The complex interactions between neoplastic cells and normal tissue, as well as the treatment-induced changes often encountered, make glioma tumor growth…

Brain tumors are abnormal cell growths in the central nervous system (CNS), and their timely detection is critical for improving patient outcomes. This paper proposes an automatic and efficient deep-learning framework for brain tumor…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ahta-Shamul Hoque Emran , Hafija Akter , Abdullah Al Shiam , Abu Saleh Musa Miah , Anichur Rahman , Fahmid Al Farid , Hezerul Abdul Karim

Anomaly detection in medical imaging is to distinguish the relevant biomarkers of diseases from those of normal tissues. Deep supervised learning methods have shown potentials in various detection tasks, but its performances would be…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Byungjai Kim , Kinam Kwon , Changheun Oh , Hyunwook Park
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