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We study how confinement transforms the chaotic dynamics of bulk microtubule-based active nematics into regular spatiotemporal patterns. For weak confinements, multiple continuously nucleating and annihilating topological defects…

Instabilities of fluid-fluid interfaces are ubiquitous in passive soft matter. Adding activity to the interface or either fluid can dramatically change the stability of the interface. Using experiment and theory, we investigate the…

Soft Condensed Matter · Physics 2026-02-04 Bennett C. Sessa , Federico Cao , Robert A. Pelcovits , Thomas R. Powers , Guillaume Duclos

We numerically investigate how spatial variations of extensile or contractile active stress affect bulk active nematic systems in two and three dimensions. In the absence of defects, activity gradients drive flows which re-orient the…

Soft Condensed Matter · Physics 2022-06-15 Liam J Ruske , Julia M Yeomans

We investigate the dynamics of an active gel of bundled microtubules that is driven by clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of thousands of molecular motors drives the gel to a highly…

Soft Condensed Matter · Physics 2015-06-23 Gil Henkin , Stephen J. DeCamp , Daniel TN Chen , Tim Sanchez , Zvonimir Dogic

Motile liquid crystal (LC) colloids show peculiar behavior due to the high sensitivity to external stimuli driven by the LC elastic and surface effects. However, few studies focus on harnessing the LC phase transitions to propel colloidal…

Mixtures of microtubules and molecular motors form active materials with diverse dynamical behaviors that vary based on their constituents' molecular properties. We map the non-equilibrium phase diagram of microtubules and tip-accumulating…

Soft Condensed Matter · Physics 2021-08-04 Bezia Lemma , Noah P. Mitchell , Radhika Subramanian , Daniel J. Needleman , Zvonimir Dogic

One of the defining features of active nematics is that above a critical activity the quiescent state becomes unstable to a distorted, flowing one. We show that spatial variations in activity can fundamentally change the nature of this…

Soft Condensed Matter · Physics 2025-12-15 Alexander J. H. Houston , Michael Grinfeld , Geoff McKay , Nigel J. Mottram

We consider a collection of self-driven apolar particles on a substrate that organize into an active nematic phase at sufficiently high density or low noise. Using the dynamical renormalization group, we systematically study the 2d…

Soft Condensed Matter · Physics 2018-02-07 Suraj Shankar , Sriram Ramaswamy , M. Cristina Marchetti

Point-like motile topological defects control the universal dynamics of diverse two-dimensional active nematics ranging from shaken granular rods to cellular monolayers. A comparable understanding in higher dimensions has yet to emerge. We…

The cytoskeleton is an active composite of filamentous proteins that dictates diverse mechanical properties and processes in eukaryotic cells by generating forces and autonomously restructuring itself. Enzymatic motors that act on the…

While studies of active nematics in two dimensions have shed light on various aspects of the flow regimes and topology of active matter, three-dimensional properties of topological defects and chaotic flows remain unexplored. By confining a…

Soft Condensed Matter · Physics 2018-07-18 Tyler N. Shendruk , Kristian Thijssen , Julia M. Yeomans , Amin Doostmohammadi

Molecular motors of the kinesin-1 family move in a directed and processive fashion along microtubules (MTs). It is generally accepted that steric hindrance of motors leads to crowding effects; however, little is known about the specific…

Biological Physics · Physics 2018-10-17 Matthias Rank , Erwin Frey

We analyze the nonlinear waves that propagate on a microtubule that is tethered at its minus end due to kinesin walking on it, as is seen during the fluid mixing caused by cytoplasmic streaming in Drosophila oocytes.The model we use assumes…

Biomolecules · Quantitative Biology 2012-07-11 J. M. Deutsch , M. E. Brunner , William M. Saxton

Numerical simulations of kinematic dynamo action in steady and 3-d ABC flows are presented with special focus on growth rates and multiple periods of the prescribed velocity field. It is found that the difference in growth rate is due to…

Astrophysics · Physics 2009-11-07 Vasilis Archontis , Bertil Dorch , Aake Nordlund

In this work, we report a direct measurement of the forces exerted by a tubulin/kinesin active nematic gel as well as its complete rheological characterization, including the quantification of its shear viscosity, {\eta}, and its activity…

Soft Condensed Matter · Physics 2024-04-22 Ignasi Vélez-Cerón , Pau Guillamat , Francesc Sagués , Jordi Ignés-Mullol

Continuum hydrodynamic models of active liquid crystals have been used to describe dynamic self-organising systems such as bacterial swarms and cytoskeletal gels. A key prediction of such models is the existence of self-stabilising kink…

Soft Condensed Matter · Physics 2009-11-13 S. A. Edwards , J. M. Yeomans

We numerically study two-dimensional active nematics with periodic activity patterning. For stripes of activity, we observe a transition from two-dimensional to one-dimensional active turbulence as the maximum active force and distance…

Soft Condensed Matter · Physics 2025-03-11 Cody D. Schimming , C. J. O. Reichhardt , C. Reichhardt

We study the dynamics of active nematic films on a substrate driven by active flows with or without the incompressible constraint.Through simulations and theoretical analysis, we show that arch patterns are stable in the compressible case,…

Soft Condensed Matter · Physics 2022-11-30 Supavit Pokawanvit , Zhitao Chen , Zhihong You , Luiza Angheluta , M. Cristina Marchetti , Mark J. Bowick

Here we study a driven lattice gas model for microtubule depolymerizing molecular motors, where traffic jams of motors induce stochastic switching between microtubule growth and shrinkage. We term this phenomenon \enquote{traffic dynamic…

Statistical Mechanics · Physics 2015-05-07 Louis Reese , Anna Melbinger , Erwin Frey

Analytical formulas for effective drift, diffusivity, run times, and run lengths are derived for an intracellular transport system consisting of a cargo attached to two cooperative but not identical molecular motors (for example, kinesin-1…

Subcellular Processes · Quantitative Biology 2021-01-22 Joseph J. Klobusicky , John Fricks , Peter R. Kramer