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We propose TAMER, a Test-time Adaptive MoE-driven framework for Electronic Health Record (EHR) Representation learning. TAMER introduces a framework where a Mixture-of-Experts (MoE) architecture is co-designed with Test-Time Adaptation…

Machine Learning · Computer Science 2025-03-19 Yinghao Zhu , Xiaochen Zheng , Ahmed Allam , Michael Krauthammer

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

In order to efficiently learn with small amount of data on new tasks, meta-learning transfers knowledge learned from previous tasks to the new ones. However, a critical challenge in meta-learning is the task heterogeneity which cannot be…

Machine Learning · Computer Science 2020-01-06 Huaxiu Yao , Xian Wu , Zhiqiang Tao , Yaliang Li , Bolin Ding , Ruirui Li , Zhenhui Li

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

Artificial Intelligence · Computer Science 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Electronic Health Records (EHR) have been heavily used in modern healthcare systems for recording patients' admission information to hospitals. Many data-driven approaches employ temporal features in EHR for predicting specific diseases,…

Machine Learning · Computer Science 2021-12-07 Chang Lu , Chandan K. Reddy , Yue Ning

Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…

Artificial Intelligence · Computer Science 2026-01-30 Lang Cao , Qingyu Chen , Yue Guo

Electronic health record (EHR) data is sparse and irregular as it is recorded at irregular time intervals, and different clinical variables are measured at each observation point. In this work, we propose a multi-view features integration…

Machine Learning · Computer Science 2021-01-27 Yurim Lee , Eunji Jun , Heung-Il Suk

Meta learning is a promising technique for solving few-shot fault prediction problems, which have attracted the attention of many researchers in recent years. Existing meta-learning methods for time series prediction, which predominantly…

Machine Learning · Computer Science 2023-11-07 Hai Su , Jiajun Hu , Songsen Yu

Electronic health record (EHR) data is an essential data source for machine learning for health, but researchers and clinicians face steep barriers in extracting and validating EHR data for modeling. Existing tools incur trade-offs between…

Human-Computer Interaction · Computer Science 2025-11-13 Ziyong Ma , Richard D. Boyce , Adam Perer , Venkatesh Sivaraman

While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records…

Machine Learning · Computer Science 2018-12-04 Satya Narayan Shukla , Benjamin M. Marlin

Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…

Machine Learning · Computer Science 2025-10-13 Tianyi Chen , Mingcheng Zhu , Zhiyao Luo , Tingting Zhu

We address the problem of predicting when a disease will develop, i.e., medical event time (MET), from a patient's electronic health record (EHR). The MET of non-communicable diseases like diabetes is highly correlated to cumulative health…

Machine Learning · Computer Science 2023-06-01 Takayuki Katsuki , Kohei Miyaguchi , Akira Koseki , Toshiya Iwamori , Ryosuke Yanagiya , Atsushi Suzuki

Background: There has been growing research interest in automated answering of questions or generation of summary of free form text such as news article. In order to implement this task, the computer should be able to identify the sequence…

Computation and Language · Computer Science 2016-07-25 Amol S Patwardhan , Jacob Badeaux , Siavash , Gerald M Knapp

Mortality prediction of diverse rare diseases using electronic health record (EHR) data is a crucial task for intelligent healthcare. However, data insufficiency and the clinical diversity of rare diseases make it hard for directly training…

Machine Learning · Computer Science 2020-05-12 Luchen Liu , Zequn Liu , Haoxian Wu , Zichang Wang , Jianhao Shen , Yiping Song , Ming Zhang

Machine Learning is proving invaluable across disciplines. However, its success is often limited by the quality and quantity of available data, while its adoption by the level of trust that models afford users. Human vs. machine performance…

Test-Time Optimization enables models to adapt to new data during inference by updating parameters on-the-fly. Recent advances in Vision-Language Models (VLMs) have explored learning prompts at test time to improve performance in downstream…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Dhruv Sarkar , Aprameyo Chakrabartty , Bibhudatta Bhanja

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

In the early observation period of a time series, there might be only a few historic observations available to learn a model. However, in cases where an existing prior set of datasets is available, Meta learning methods can be applicable.…

Machine Learning · Computer Science 2023-07-20 Shayan Jawed , Kiran Madhusudhanan , Vijaya Krishna Yalavarthi , Lars Schmidt-Thieme

Conventional machine learning models, particularly tree-based approaches, have demonstrated promising performance across various clinical prediction tasks using electronic health record (EHR) data. Despite their strengths, these models…

Computation and Language · Computer Science 2025-05-26 Sara Ketabi , Dhanesh Ramachandram