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The paper tackles the problem of clustering multiple networks, directed or not, that do not share the same set of vertices, into groups of networks with similar topology. A statistical model-based approach based on a finite mixture of…

Statistics Theory · Mathematics 2023-11-07 Tabea Rebafka

Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

Modeling relations between individuals is a classical question in social sciences and clustering individuals according to the observed patterns of interactions allows to uncover a latent structure in the data. Stochastic block model (SBM)…

Methodology · Statistics 2015-01-27 Pierre Barbillon , Sophie Donnet , Emmanuel Lazega , Avner Bar-Hen

Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite…

Methodology · Statistics 2012-11-12 Michael A. Newton , Lisa M. Chung

The simultaneous grouping of rows and columns is an important technique that is increasingly used in large-scale data analysis. In this paper, we present a novel co-clustering method using co-variables in its construction. It is based on a…

Applications · Statistics 2018-12-21 Serge Iovleff , Seydou Syllla , Cheikh Loucoubar

Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…

Methodology · Statistics 2025-07-22 Kazeem Kareem , Fan Dai

The expression levels of many thousands of genes can be measured simultaneously by DNA microarrays (chips). This novel experimental tool has revolutionized research in molecular biology and generated considerable excitement. A typical…

Biological Physics · Physics 2007-05-23 Eytan Domany

Scoring patent documents is very useful for technology management. However, conventional methods are based on static models and, thus, do not reflect the growth potential of the technology cluster of the patent. Because even if the cluster…

Analysis of single-cell transcriptomics often relies on clustering cells and then performing differential gene expression (DGE) to identify genes that vary between these clusters. These discrete analyses successfully determine cell types…

Quantitative Methods · Quantitative Biology 2022-10-07 Renee S. Hoekzema , Lewis Marsh , Otto Sumray , Thomas M. Carroll , Xin Lu , Helen M. Byrne , Heather A. Harrington

Molecular and genomic technological advancements have greatly enhanced our understanding of biological processes by allowing us to quantify key biological variables such as gene expression, protein levels, and microbiome compositions. These…

Methodology · Statistics 2024-06-12 Mingyu Du , Kevin Johnston , Veronica Berrocal , Wei Li , Xiangmin Xu , Zhaoxia Yu

In this paper, we propose a novel multi-view clustering model, named Dual-space Co-training Large-scale Multi-view Clustering (DSCMC). The main objective of our approach is to enhance the clustering performance by leveraging co-training in…

Machine Learning · Computer Science 2024-01-30 Zisen Kong , Zhiqiang Fu , Dongxia Chang , Yiming Wang , Yao Zhao

Clustering the nodes of a graph allows the analysis of the topology of a network. The stochastic block model is a clustering method based on a probabilistic model. Initially developed for binary networks it has recently been extended to…

Computation · Statistics 2014-02-17 Jean-Benoist Leger

A model based clustering procedure for data of mixed type, clustMD, is developed using a latent variable model. It is proposed that a latent variable, following a mixture of Gaussian distributions, generates the observed data of mixed type.…

Methodology · Statistics 2015-11-06 Damien McParland , Isobel Claire Gormley

In this work, we propose an original method for aggregating multiple clustering coming from different sources of information. Each partition is encoded by a co-membership matrix between observations. Our approach uses a mixture of…

Machine Learning · Computer Science 2024-01-10 Kylliann De Santiago , Marie Szafranski , Christophe Ambroise

Recent advances in biological research have seen the emergence of high-throughput technologies with numerous applications that allow the study of biological mechanisms at an unprecedented depth and scale. A large amount of genomic data is…

Machine Learning · Statistics 2020-05-11 Nanwei Wang , Laurent Briollais , Helene Massam

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

Methodology · Statistics 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

As single-cell gene expression data analysis continues to grow, the need for reliable clustering methods has become increasingly important. The prevalence of heuristic means for method choice could lead to inaccurate reports if…

Quantitative Methods · Quantitative Biology 2026-05-19 Owen Visser , Somnath Datta

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

We consider the problem of clustering grouped data for which the observations may include group-specific variables in addition to the variables that are shared across groups. This type of data is common in cancer genomics where the…

Methodology · Statistics 2025-09-30 Arhit Chakrabarti , Yang Ni , Debdeep Pati , Bani K. Mallick

We present and review Coupled Two Way Clustering, a method designed to mine gene expression data. The method identifies submatrices of the total expression matrix, whose clustering analysis reveals partitions of samples (and genes) into…

Biological Physics · Physics 2007-05-23 Gad Getz , Hilah Gal , Itai Kela , Eytan Domany , Dan A. Notterman