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This paper considers the estimation of treatment effects in randomized experiments with complex experimental designs, including cases with interference between units. We develop a design-based estimation theory for arbitrary experimental…

Econometrics · Economics 2025-05-27 Haoge Chang

Accurate simulation of complex physical systems enables the development, testing, and certification of control strategies before they are deployed into the real systems. As simulators become more advanced, the analytical tractability of the…

Robotics · Computer Science 2020-05-27 Lucas Barcelos , Rafael Oliveira , Rafael Possas , Lionel Ott , Fabio Ramos

The widespread availability of off-the-shelf machine learning models poses a challenge: which model, of the many available candidates, should be chosen for a given data analysis task? This question of model selection is traditionally…

Machine Learning · Computer Science 2025-08-01 Justin Kay , Grant Van Horn , Subhransu Maji , Daniel Sheldon , Sara Beery

Both the human brain and artificial learning agents operating in real-world or comparably complex environments are faced with the challenge of online model selection. In principle this challenge can be overcome: hierarchical Bayesian…

Machine Learning · Computer Science 2017-12-05 David G. Nagy , Gergő Orbán

Instructional designers face an overwhelming array of design choices, making it challenging to identify the most effective interventions. To address this issue, I propose the concept of a Model Human Learner, a unified computational model…

Human-Computer Interaction · Computer Science 2025-05-13 Christopher J. MacLellan

Recently Quantum Computation has generated a lot of interest due to the discovery of a quantum algorithm which can factor large numbers in polynomial time. The usefulness of a quantum com puter is limited by the effect of errors. Simulation…

Quantum Physics · Physics 2007-05-23 Kevin M. Obenland , Alvin M. Despain

We develop a new computational approach for "focused" optimal Bayesian experimental design with nonlinear models, with the goal of maximizing expected information gain in targeted subsets of model parameters. Our approach considers…

Computation · Statistics 2019-03-28 Chi Feng , Youssef M. Marzouk

Space-filling designs are crucial for efficient computer experiments, enabling accurate surrogate modeling and uncertainty quantification in many scientific and engineering applications, such as digital twin systems and cyber-physical…

Methodology · Statistics 2025-08-06 Xinwei Deng , Lulu Kang , C. Devon Lin

A high-ranking goal of interdisciplinary modeling approaches in the natural sciences are quantitative prediction of system dynamics and model based optimization. For this purpose, mathematical modeling, numerical simulation and scientific…

Optimization and Control · Mathematics 2015-03-17 Dominik Skanda , Dirk Lebiedz

There is a growing trend in molecular and synthetic biology of using mechanistic (non machine learning) models to design biomolecular networks. Once designed, these networks need to be validated by experimental results to ensure the…

Quantitative Methods · Quantitative Biology 2020-11-26 Ruby Sedgwick , John Goertz , Molly Stevens , Ruth Misener , Mark van der Wilk

In sequential experiments, subjects become available for the study over a period of time, and covariates are often measured at the time of arrival. We consider the setting where the sample size is fixed but covariate values are unknown…

Methodology · Statistics 2020-05-28 Mia S. Tackney , David C. Woods , Ilya Shpitser

Causal structure learning is a key problem in many domains. Causal structures can be learnt by performing experiments on the system of interest. We address the largely unexplored problem of designing a batch of experiments that each…

Machine Learning · Computer Science 2021-11-25 Scott Sussex , Andreas Krause , Caroline Uhler

Computer simulators can be computationally intensive to run over a large number of input values, as required for optimization and various uncertainty quantification tasks. The standard paradigm for the design and analysis of computer…

Computation · Statistics 2015-09-11 Joakim Beck , Serge Guillas

Simulation can enable the study of recommender system (RS) evolution while circumventing many of the issues of empirical longitudinal studies; simulations are comparatively easier to implement, are highly controlled, and pose no ethical…

Computers and Society · Computer Science 2021-08-02 Amy A. Winecoff , Matthew Sun , Eli Lucherini , Arvind Narayanan

Finite-horizon sequential experimental design (SED) arises naturally in many contexts, including hyperparameter tuning in machine learning among more traditional settings. Computing the optimal policy for such problems requires solving…

Machine Learning · Computer Science 2020-02-11 Shali Jiang , Henry Chai , Javier Gonzalez , Roman Garnett

Simulation methods are among the most ubiquitous methodological tools in statistical science. In particular, statisticians often is simulation to explore properties of statistical functionals in models for which developed statistical theory…

Methodology · Statistics 2023-08-22 Tyrel Stokes , Ian Shrier , Russell Steele

Simulation-based optimization of complex systems over discrete decision spaces is a challenging computational problem. Specifically, discrete decision spaces lead to a combinatorial explosion of possible alternatives, making it…

Optimization and Control · Mathematics 2025-10-17 Gabriel Hernández-Morales , Brenda Cansino-Loeza , Arturo Jiménez-Gutiérrez , Victor M. Zavala

We consider in this paper the problem of optimal experiment design where a decision maker can choose which points to sample to obtain an estimate $\hat{\beta}$ of the hidden parameter $\beta^{\star}$ of an underlying linear model. The key…

Machine Learning · Statistics 2021-01-01 Xavier Fontaine , Pierre Perrault , Michal Valko , Vianney Perchet

Offline model-based reinforcement learning (MBRL) serves as a competitive framework that can learn well-performing policies solely from pre-collected data with the help of learned dynamics models. To fully unleash the power of offline MBRL,…

Machine Learning · Computer Science 2025-02-18 Yu-Wei Yang , Yun-Ming Chan , Wei Hung , Xi Liu , Ping-Chun Hsieh

We develop a qualitative model of decision making with two aims: to describe how people make simple decisions and to enable computer programs to do the same. Current approaches based on Planning or Decisions Theory either ignore uncertainty…

Artificial Intelligence · Computer Science 2013-02-18 Blai Bonet , Hector Geffner