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Machine learning in neurosurgery is limited by challenges in assembling large, high-quality imaging datasets. Synthetic data offers a scalable, privacy-preserving solution. We evaluated the feasibility of generating realistic lateral…

The development of generative models in the past decade has allowed for hyperrealistic data synthesis. While potentially beneficial, this synthetic data generation process has been relatively underexplored in cancer histopathology. One…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Aakash Madhav Rao , Debayan Gupta

Data scarcity and privacy concerns limit the availability of high-quality medical images for public use, which can be mitigated through medical image synthesis. However, current medical image synthesis methods often struggle to accurately…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Wenting Chen , Pengyu Wang , Hui Ren , Lichao Sun , Quanzheng Li , Yixuan Yuan , Xiang Li

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

Synthesizing realistic medical images provides a feasible solution to the shortage of training data in deep learning based medical image recognition systems. However, the quality control of synthetic images for data augmentation purposes is…

Computer Vision and Pattern Recognition · Computer Science 2020-08-27 Jiarong Ye , Yuan Xue , L. Rodney Long , Sameer Antani , Zhiyun Xue , Keith Cheng , Xiaolei Huang

Deep learning-based medical image processing algorithms require representative data during development. In particular, surgical data might be difficult to obtain, and high-quality public datasets are limited. To overcome this limitation and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Siyuan Mei , Fuxin Fan , Fabian Wagner , Mareike Thies , Mingxuan Gu , Yipeng Sun , Andreas Maier

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Recently, medical image synthesis gains more and more popularity, along with the rapid development of generative models. Medical image synthesis aims to generate an unacquired image modality, often from other observed data modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-04 Zhe Xiong , Qiaoqiao Ding , Xiaoqun Zhang

Multimodal self-supervised representation learning has consistently proven to be a highly effective method in medical image analysis, offering strong task performance and producing biologically informed insights. However, these methods…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Lucas Farndale , Chris Walsh , Robert Insall , Ke Yuan

Generative Adversarial Networks (GANs) have shown considerable promise for mitigating the challenge of data scarcity when building machine learning-driven analysis algorithms. Specifically, a number of studies have shown that GAN-based…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Xiaodan Hu , Audrey G. Chung , Paul Fieguth , Farzad Khalvati , Masoom A. Haider , Alexander Wong

Generative models are becoming popular for the synthesis of medical images. Recently, neural diffusion models have demonstrated the potential to generate photo-realistic images of objects. However, their potential to generate medical images…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Hazrat Ali , Shafaq Murad , Zubair Shah

Conditional image synthesis based on user-specified requirements is a key component in creating complex visual content. In recent years, diffusion-based generative modeling has become a highly effective way for conditional image synthesis,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Zheyuan Zhan , Defang Chen , Jian-Ping Mei , Zhenghe Zhao , Jiawei Chen , Chun Chen , Siwei Lyu , Can Wang

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Accurate single cell detection in brightfield microscopy is crucial for biological research, yet data scarcity and annotation bottlenecks limit the progress of deep learning methods. We investigate the use of unconditional models to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Mario de Jesus da Graca , Jörg Dahlkemper , Peer Stelldinger

Image synthesis approaches, e.g., generative adversarial networks, have been popular as a form of data augmentation in medical image analysis tasks. It is primarily beneficial to overcome the shortage of publicly accessible data and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Shiyi Du , Xiaosong Wang , Yongyi Lu , Yuyin Zhou , Shaoting Zhang , Alan Yuille , Kang Li , Zongwei Zhou

This study explores the utilization of Dermatoscopic synthetic data generated through stable diffusion models as a strategy for enhancing the robustness of machine learning model training. Synthetic data generation plays a pivotal role in…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Muhammad Ali Farooq , Wang Yao , Michael Schukat , Mark A Little , Peter Corcoran

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias