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Multiple stains are usually used to highlight biological substances in biomedical image analysis. To decompose multiple stains for co-localization quantification, blind source separation is usually performed. Prior model-based stain…

Image and Video Processing · Electrical Eng. & Systems 2021-02-16 Xingyu Li

Deep learning-based virtual staining was developed to introduce image contrast to label-free tissue sections, digitally matching the histological staining, which is time-consuming, labor-intensive, and destructive to tissue. Standard…

Image and Video Processing · Electrical Eng. & Systems 2022-10-31 Yijie Zhang , Luzhe Huang , Tairan Liu , Keyi Cheng , Kevin de Haan , Yuzhu Li , Bijie Bai , Aydogan Ozcan

In this work, we explore the potential of self-supervised learning with Generative Adversarial Networks (GANs) for electron microscopy datasets. We show how self-supervised pretraining facilitates efficient fine-tuning for a spectrum of…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Bashir Kazimi , Karina Ruzaeva , Stefan Sandfeld

Generative Adversarial Networks (GANs) have been used in several machine learning tasks such as domain transfer, super resolution, and synthetic data generation. State-of-the-art GANs often use tens of millions of parameters, making them…

Machine Learning · Computer Science 2019-02-04 Angeline Aguinaldo , Ping-Yeh Chiang , Alex Gain , Ameya Patil , Kolten Pearson , Soheil Feizi

Convolutional Neural Networks (CNNs) are prone to overfit small training datasets. We present a novel two-phase pipeline that leverages self-supervised learning and knowledge distillation to improve the generalization ability of CNN models…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Bingchen Zhao , Xin Wen

The success of deep learning in computer vision is rooted in the ability of deep networks to scale up model complexity as demanded by challenging visual tasks. As complexity is increased, so is the need for large amounts of labeled data to…

Computer Vision and Pattern Recognition · Computer Science 2017-08-22 Gustav Larsson

Knowledge distillation (KD) has been actively studied for image classification tasks in deep learning, aiming to improve the performance of a student based on the knowledge from a teacher. However, applying KD in image regression with a…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Xin Ding , Yongwei Wang , Zuheng Xu , Z. Jane Wang , William J. Welch

Color inconsistency is an inevitable challenge in computational pathology, which generally happens because of stain intensity variations or sections scanned by different scanners. It harms the pathological image analysis methods, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Bingchao Zhao , Jiatai Lin , Changhong Liang , Zongjian Yi , Xin Chen , Bingbing Li , Weihao Qiu , Danyi Li , Li Liang , Chu Han , Zaiyi Liu

In recent years, supervised learning with convolutional networks (CNNs) has seen huge adoption in computer vision applications. Comparatively, unsupervised learning with CNNs has received less attention. In this work we hope to help bridge…

Machine Learning · Computer Science 2016-01-11 Alec Radford , Luke Metz , Soumith Chintala

The emergence of virtual staining technology provides a rapid and efficient alternative for researchers in tissue pathology. It enables the utilization of unlabeled microscopic samples to generate virtual replicas of chemically stained…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Junjia Wang , Bo Xiong , You Zhou , Xun Cao , Zhan Ma

Disentangled generative models map a latent code vector to a target space, while enforcing that a subset of the learned latent codes are interpretable and associated with distinct properties of the target distribution. Recent advances have…

Machine Learning · Computer Science 2020-08-10 Zinan Lin , Kiran Koshy Thekumparampil , Giulia Fanti , Sewoong Oh

Knowledge distillation has been widely used to produce portable and efficient neural networks which can be well applied on edge devices for computer vision tasks. However, almost all top-performing knowledge distillation methods need to…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Haoran Zhao , Xin Sun , Junyu Dong , Hui Yu , Huiyu Zhou

Deep Learning has emerged as a promising approach for skin lesion analysis. However, existing methods mostly rely on fully supervised learning, requiring extensive labeled data, which is challenging and costly to obtain. To alleviate this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Siyamalan Manivannan

Visualizing the details of different cellular structures is of great importance to elucidate cellular functions. However, it is challenging to obtain high quality images of different structures directly due to complex cellular environments.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Yi Liu , Hao Yuan , Zhengyang Wang , Shuiwang Ji

We propose a new deep learning approach for medical imaging that copes with the problem of a small training set, the main bottleneck of deep learning, and apply it for classification of healthy and cancer cells acquired by quantitative…

Image and Video Processing · Electrical Eng. & Systems 2018-12-31 Moran Rubin , Omer Stein , Nir A. Turko , Yoav Nygate , Darina Roitshtain , Lidor Karako , Itay Barnea , Raja Giryes , Natan T. Shaked

It's useful to automatically transform an image from its original form to some synthetic form (style, partial contents, etc.), while keeping the original structure or semantics. We define this requirement as the "image-to-image translation"…

Computer Vision and Pattern Recognition · Computer Science 2017-01-11 Hao Dong , Paarth Neekhara , Chao Wu , Yike Guo

Stain normalization often refers to transferring the color distribution of the source image to that of the target image and has been widely used in biomedical image analysis. The conventional stain normalization is regarded as constructing…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Hongtao Kang , Die Luo , Weihua Feng , Junbo Hu , Shaoqun Zeng , Tingwei Quan , Xiuli Liu

Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Amirata Ghorbani , Vivek Natarajan , David Coz , Yuan Liu

The use of accurate scanning transmission electron microscopy (STEM) image simulation methods require large computation times that can make their use infeasible for the simulation of many images. Other simulation methods based on linear…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Nick Lawrence , Mingren Shen , Ruiqi Yin , Cloris Feng , Dane Morgan

Detecting changed regions in paired satellite images plays a key role in many remote sensing applications. The evolution of recent techniques could provide satellite images with very high spatial resolution (VHR) but made it challenging to…

Image and Video Processing · Electrical Eng. & Systems 2021-12-08 Caijun Ren , Xiangyu Wang , Jian Gao , Huanhuan Chen