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Transportability analysis is a causal inference framework used to evaluate the external validity of randomized clinical trials (RCTs) or observational studies. Most existing transportability analysis methods require individual patient-level…

Methodology · Statistics 2025-07-09 Yichen Yan , Quang Vuong , Rebecca K Metcalfe , Tianyu Guan , Haolun Shi , Jay JH Park

While much of the causal inference literature has focused on addressing internal validity biases, both internal and external validity are necessary for unbiased estimates in a target population of interest. However, few generalizability…

Methodology · Statistics 2023-04-07 Irina Degtiar , Tim Layton , Jacob Wallace , Sherri Rose

Randomized trials are widely considered as the gold standard for evaluating the effects of decision policies. Trial data is, however, drawn from a population which may differ from the intended target population and this raises a problem of…

Methodology · Statistics 2024-10-30 Sofia Ek , Dave Zachariah

Epidemic models often reflect characteristic features of infectious spreading processes by coupled non-linear differential equations considering different states of health (such as Susceptible, Infected, or Recovered). This compartmental…

Physics and Society · Physics 2021-12-01 Vaiva Vasiliauskaite , Nino Antulov-Fantulin , Dirk Helbing

Objective: To investigate the impact of different logistic regression estimators applied to RDS samples obtained by simulation and real data. Methods: Four simulated populations were created combining different connectivity models, levels…

Transportability, the ability to maintain performance across populations, is a desirable property of markers of clinical outcomes. However, empirical findings indicate that markers often exhibit varying performances across populations. For…

Applications · Statistics 2025-12-01 Mohsen Sadatsafavi , Gavin Pereira , Wenjia Chen

Positivity is one of the three conditions for causal inference from observational data. The standard way to validate positivity is to analyze the distribution of propensity. However, to democratize the ability to do causal inference by…

Machine Learning · Computer Science 2021-11-09 Guy Wolf , Gil Shabat , Hanan Shteingart

Matching on covariates is a well-established framework for estimating causal effects in observational studies. The principal challenge stems from the often high-dimensional structure of the problem. Many methods have been introduced to…

Methodology · Statistics 2022-07-12 Florian Gunsilius , Yuliang Xu

Many lifestyle intervention trials depend on collecting self-reported outcomes, like dietary intake, to assess the intervention's effectiveness. Self-reported outcome measures are subject to measurement error, which could impact treatment…

Methodology · Statistics 2020-04-06 Benjamin Ackerman , Juned Siddique , Elizabeth A. Stuart

Estimating causal effects in a target population with unmeasured confounders is challenging, especially when instrumental variables (IVs) are unavailable. However, IVs from auxiliary populations with similar problems can help infer causal…

Methodology · Statistics 2025-08-06 Wei Li , Jiapeng Liu , Peng Ding , Zhi Geng

In recent years, there has been a surge in the development of models for the generation of synthetic mobility data. These models aim to facilitate the sharing of data while safeguarding privacy, all while ensuring high utility and…

Cryptography and Security · Computer Science 2024-07-04 Alexandra Kapp , Helena Mihaljević

Although highly valuable for a variety of applications, urban mobility data is rarely made openly available as it contains sensitive personal information. Synthetic data aims to solve this issue by generating artificial data that resembles…

Cryptography and Security · Computer Science 2024-07-15 Alexandra Kapp , Julia Hansmeyer , Helena Mihaljević

We discuss the identifiability of causal estimands for generalizability and transportability analyses, both under perfect and imperfect adherence to treatment assignment. We consider a setting where the trial data contain information on…

Methodology · Statistics 2022-11-10 Issa J. Dahabreh , Sarah E. Robertson , Miguel A. Hernán

When examining a contrast between two interventions, longitudinal causal inference studies frequently encounter positivity violations when one or both regimes are impossible to observe for some subjects. Existing weighting methods either…

Methodology · Statistics 2025-08-11 Alec McClean , Iván Díaz

Hierarchically-organized data arise naturally in many psychology and neuroscience studies. As the standard assumption of independent and identically distributed samples does not hold for such data, two important problems are to accurately…

Statistics Theory · Mathematics 2018-09-03 Irene Dowding , Stefan Haufe

In this paper, we present a comprehensive survey of human-mobility modeling based on 1680 articles published between 1999 and 2019, which can serve as a roadmap for research and practice in this area. Mobility modeling research has…

Social and Information Networks · Computer Science 2019-06-19 Vaibhav Kulkarni , Benoit Garbinato

When the distribution of treatment effect modifiers differs between the trial sample and target population, inverse probability weighting (IPSW) can be applied to achieve an unbiased estimate of the population average treatment effect in…

Applications · Statistics 2022-03-04 Albee Y. Ling , Maria E. Montez-Rath , Kris Kapphahn , Manisha Desai

The problem of generalization and transportation of treatment effect estimates from a study sample to a target population is central to empirical research and statistical methodology. In both randomized experiments and observational…

Methodology · Statistics 2023-06-19 Ambarish Chattopadhyay , Eric R. Cohn , Jose R. Zubizarreta

Non-probability samples become increasingly popular in survey statistics but may suffer from selection biases that limit the generalizability of results to the target population. We consider integrating a non-probability sample with a…

Methodology · Statistics 2019-08-26 Shu Yang , Jae Kwang Kim , Rui Song

A standard assumption for causal inference from observational data is that one has measured a sufficiently rich set of covariates to ensure that within covariate strata, subjects are exchangeable across observed treatment values. Skepticism…

Methodology · Statistics 2020-09-24 Eric J Tchetgen Tchetgen , Andrew Ying , Yifan Cui , Xu Shi , Wang Miao
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