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Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed…

Anatomy shape modeling is a fundamental problem in medical data analysis. However, the geometric complexity and topological variability of anatomical structures pose significant challenges to accurate anatomical shape generation. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Guoqing Zhang , Jingyun Yang , Siqi Chen , Anping Zhang , Yang Li

Different imaging modalities are used to extract the diverse information carried in an optical field. Two prominent modalities include bright field and phase contrast microscopy that can visualize the amplitude and phase features of a…

Fine-grained classification and counting of bone marrow erythroid cells are vital for evaluating the health status and formulating therapeutic schedules for leukemia or hematopathy. Due to the subtle visual differences between different…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Ye Wang , Rui Ma , Xiaoqing Ma , Honghua Cui , Yubin Xiao , Xuan Wu , You Zhou

We present a deep learning driven computational approach to overcome the limitations of self-interference digital holography that imposed by inferior axial imaging performances. We demonstrate a 3D deep neural network model can…

Understanding the structure of a protein complex is crucial indetermining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are two-dimensional.…

Quantitative Methods · Quantitative Biology 2021-10-18 Benjamin J. Blundell , Christian Sieben , Suliana Manley , Ed Rosten , QueeLim Ch'ng , Susan Cox

We propose a novel 3D shape correspondence method based on the iterative alignment of so-called smooth shells. Smooth shells define a series of coarse-to-fine shape approximations designed to work well with multiscale algorithms. The main…

Computer Vision and Pattern Recognition · Computer Science 2019-12-03 Marvin Eisenberger , Zorah Lähner , Daniel Cremers

Endovascular navigation, essential for diagnosing and treating endovascular diseases, predominantly hinges on fluoroscopic images due to the constraints in sensory feedback. Current shape reconstruction techniques for endovascular…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Tudor Jianu , Baoru Huang , Pierre Berthet-Rayne , Sebastiano Fichera , Anh Nguyen

CNN-based volumetric methods that label individual voxels now dominate the field of biomedical segmentation. However, 3D surface representations are often required for proper analysis. They can be obtained by post-processing the labeled…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Udaranga Wickramasinghe , Edoardo Remelli , Graham Knott , Pascal Fua

In this work, we describe a method for large-scale 3D cell-tracking through a segmentation selection approach. The proposed method is effective at tracking cells across large microscopy datasets on two fronts: (i) It can solve problems…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Jordão Bragantini , Merlin Lange , Loïc Royer

Microstructure reconstruction has been an essential part of computational material engineering to reveal the relationship between microstructures and material properties. However, finding a general solution for microstructure…

Materials Science · Physics 2023-01-24 Kang-Hyun Lee , Gun Jin Yun

Optical images of transparent three-dimensional objects can be different from a replica of the object's cross section in the image plane due to refraction at the surface or in the body of the object. Simulations of the object's image are…

In many laboratories, conventional bright-field transmission microscopes are available to study the structure and organization principles of fibrous tissue samples, but they usually provide only 2D information. To access the third…

Ptychography is a popular imaging technique that combines diffractive imaging with scanning microscopy. The technique consists of a coherent beam that is scanned across an object in a series of overlapping positions, leading to reliable and…

Numerical Analysis · Mathematics 2019-02-20 Samy Wu Fung , Zichao Di

Molecular shape and geometry dictate key biophysical recognition processes, yet many graph neural networks disregard 3D information for molecular property prediction. Here, we propose a new contrastive-learning procedure for graph neural…

Machine Learning · Computer Science 2022-11-07 Austin Atsango , Nathaniel L. Diamant , Ziqing Lu , Tommaso Biancalani , Gabriele Scalia , Kangway V. Chuang

Analysis of three-dimensional biological samples is critical to understanding tissue function and the mechanisms of disease. Many chronic conditions, like neurodegenerative diseases and cancers, correlate with complex tissue changes that…

Biological Physics · Physics 2019-11-06 Jiaming Guo , Camille Artur , Jason L. Eriksen , David Mayerich

In this thesis, we discuss the design and calibration (geometric and radiometric) of a novel shape and reflectance acquisition device called the "Multispectral Light Stage". This device can capture highly detailed facial geometry (down to…

Computer Vision and Pattern Recognition · Computer Science 2011-05-19 Abhishek Dutta

Transparent objects are a common part of everyday life, yet they possess unique visual properties that make them incredibly difficult for standard 3D sensors to produce accurate depth estimates for. In many cases, they often appear as noisy…

Computer Vision and Pattern Recognition · Computer Science 2019-10-16 Shreeyak S. Sajjan , Matthew Moore , Mike Pan , Ganesh Nagaraja , Johnny Lee , Andy Zeng , Shuran Song

Deep learning-based 3-dimensional (3D) shape reconstruction from 2-dimensional (2D) magnetic resonance imaging (MRI) has become increasingly important in medical disease diagnosis, treatment planning, and computational modeling. This review…

Machine Learning · Computer Science 2025-10-03 Emma McMillian , Abhirup Banerjee , Alfonso Bueno-Orovio

We present a new effective way for performance capture of deforming meshes with fine-scale time-varying surface detail from multi-view video. Our method builds up on coarse 4D surface reconstructions, as obtained with commonly used…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Nadia Robertini , Edilson De Aguiar , Thomas Helten , Christian Theobalt