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There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…
Many engineering and physiological applications deal with situations when a fluid is moving in flexible tubes with elastic walls. In the real-life applications like blood flow, there is often an additional complexity of vorticity being…
Cessation of flow in simple yield stress fluids results in a complex stress relaxation process that depends on the preceding flow conditions and leads to finite residual stresses. To assess the microscopic origin of this phenomenon, we…
A minimal model for studying the mechanical properties of amorphous solids is a disordered network of point masses connected by unbreakable springs. At a critical value of its mean connectivity, such a network becomes fragile: it undergoes…
Flow of cerebrospinal fluid in perivascular spaces is a key mechanism underlying brain transport and clearance. In this paper, we present a mathematical and numerical formalism for reduced models of pulsatile viscous fluid flow in networks…
In this work, we present a coupled 3D-1D model of solid tumor growth within a dynamically changing vascular network to facilitate realistic simulations of angiogenesis. Additionally, the model includes erosion of the extracellular matrix,…
Direct numerical simulations of turbulent flow in a channel with one rigid and one viscoelastic wall are performed. An Eulerian-Eulerian model is adopted with a level-set approach to identify the fluid-compliant material interface. Focus is…
In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…
Stability of coarse particles against gravity is an important issue in dense suspensions (fresh concrete, foodstuff, etc.). On the one hand, it is known that they are stable at rest when the interstitial paste has a high enough yield…
Diffusivity is a key quantity in describing velocity fluctuations in granular materials. These fluctuations are the basis of many thermodynamic and hydrodynamic models which aim to provide a statistical description of granular systems. We…
We discuss the characteristics of the patterns of the vascular networks in a mathematical model for angiogenesis. Based on recent in vitro experiments, this mathematical model assumes that the elongation and bifurcation of blood vessels…
The effect on the transport properties of fractures of a relative shear displacement $\vec u$ of rough walls with complementary self-affine surfaces has been studied experimentally and numerically. The shear displacement $\vec u$ induces an…
Conjugation accelerates bacterial evolution by enabling bacteria to acquire genes horizontally from their neighbors. Plasmid donors must physically encounter and connect with recipients to allow plasmid transfer, and different environments…
Microorganism motility often takes place within complex, viscoelastic fluid environments, e.g., sperm in cervicovaginal mucus and bacteria in biofilms. In such complex fluids, strains and stresses generated by the microorganism are stored…
Two-dimensional Particle Tracking Velocimetry (PTV) is a promising technique to study the behaviour of granular flows. The aim is to experimentally determine the free surface width and position of the shear band from the velocity profile to…
We study the rheology of a two-fluid emulsion in semi-concentrated conditions; the solute is Newtonian while the solvent an inelastic power law fluid. The problem at hand is tackled by means of direct numerical simulations using the volume…
Using a minimal hydrodynamic model, we theoretically and computationally study active gels in straight and annular two-dimensional channels subject to an externally imposed shear. The gels are isotropic in the absence of externally- or…
The dynamical mechanical analysis of blood generally uses models inspired by conventional flows, assuming scale-independent homogeneous flows and without considering fluid-surface boundary interactions. The present experimental study…
The true slime mould Physarum polycephalum is a recent well studied example of how complex transport networks emerge from simple auto-catalytic and self- organising local interactions, adapting structure and function against changing…
Elastic confinements play an important role in many soft matter systems and affect the transport properties of suspended particles in viscous flow. On the basis of low-Reynolds-number hydrodynamics, we present an analytical theory of the…