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We study the flow of a shear-thinning, chemically-reacting fluid that could be used to model the flow of the synovial fluid. The actual geometry where the flow of the synovial fluid takes place is very complicated, and therefore the…

Numerical Analysis · Computer Science 2014-09-01 Craig Bridges , Satish Karra , K. R. Rajagopal

Motivated by the treatment of varicose veins with aqueous foams, we determine the velocity profiles and yield surface positions for pressure-driven flows of a Bingham fluid in curved channels, incorporating Navier wall slip to capture the…

Fluid Dynamics · Physics 2026-04-03 S. J. Cox , S. M. Taghavi

Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of the vascular tree. Shear-thinning is intimately related to the dynamics and mutual interactions of red blood cells (RBCs), the major…

Active fluid transport is a hallmark of many biological transport networks. While animal circulatory systems generally rely on a single heart to drive flows, other organisms employ decentralized local pumps to distribute fluids and…

Biological Physics · Physics 2024-01-04 Adam B. Dionne , Katharine E. Jensen , Henrik Ronellenfitsch

We study the local dynamics of a thixotropic yield stress fluid that shows a pronounced non-monotonic flow curve. This mechanically unstable behavior is generally not observable from standard rheometry tests, resulting in a stress plateau…

Soft Condensed Matter · Physics 2024-11-04 Michela Geri , Brice Saint-Michel , Thibaut Divoux , Gareth H. McKinley , Sebastien Manneville

A fundamental question regarding biological transport networks is the interplay between the network development or reorganization and the flows it carries. We use Physarum polycephalum, a true slime mould with a transport network which…

Biological Physics · Physics 2022-12-27 Raphaël Saiseau , Valentin Busson , Laura Xénard , Marc Durand

As nutrients travel through microcirculation and are absorbed, their availability continuously decreases. However, a uniform nutrient distribution is critical, as it prevents tissue death in poorly supplied areas. How, then, do vascular…

Tissues and Organs · Quantitative Biology 2024-11-18 Georgios Gounaris , Mija Jovchevska , Miguel Ruiz Garcia , Eleni Katifori

We investigate crystal-growth kinetics in the presence of strong shear flow in the liquid, using molecular-dynamics simulations of a binary-alloy model. Close to the equilibrium melting point, shear flow always suppresses the growth of the…

Materials Science · Physics 2017-08-15 H. L. Peng , D. M. Herlach , Th. Voigtmann

Motivated by the complex rheological behaviors observed in small/micro scale blood vessels, such as the Fahraeus effect, plasma-skimming, shear-thinning, etc., we develop a non-linear suspension model for blood. The viscosity is assumed to…

Fluid Dynamics · Physics 2018-12-26 Wei-Tao Wu , Nadine Aubry , James F. Antaki , Mehrdad Massoudi

Controlling bacterial surface adhesion and subsequent biofilm formation in fluid systems is crucial for the safety and efficacy of medical and industrial processes. Here, we theoretically examine the transport of bacteria close to surfaces,…

Soft Condensed Matter · Physics 2025-07-08 Edwina F. Yeo , Benjamin J. Walker , Philip Pearce , Mohit P. Dalwadi

The rheological behavior of polymer melts is strongly influenced by parameters such as chain length, chain stiffness, and architecture. In particular, shear thinning, characterized by a power-law decrease in shear viscosity with increasing…

Soft Condensed Matter · Physics 2026-03-17 Yuhi Sakamaki , Shota Goto , Kang Kim , Nobuyuki Matubayasi

Viscous flows through configurations manufactured from soft materials apply both pressure and shear stress at the solid-liquid interface, leading to deformation of the cross-section, which affects the flow rate-pressure drop relation.…

Fluid Dynamics · Physics 2022-09-29 Evgeniy Boyko , Howard A. Stone , Ivan C. Christov

Understanding of vascular organization is a long-standing problem in quantitative biology and biophysics and is essential for the growth of large cultured tissues. Approaches are needed that (1) make predictions of optimal arteriovenous…

Tissues and Organs · Quantitative Biology 2023-08-25 James P. Hague

Cord-forming fungi form extensive networks that continuously adapt to maintain an efficient transport system. As osmotically driven water uptake is often distal from the tips, and aqueous fluids are incompressible, we propose that growth…

Tissues and Organs · Quantitative Biology 2010-05-31 Luke Heaton , Eduardo Lopez , Philip K. Maini , Mark D. Fricker , Nick S. Jones

The structure of flow networks determines their function under normal conditions as well as their response to perturbative damage. Brain vasculature often experiences transient or permanent occlusions in the finest vessels, but it is not…

Disordered Systems and Neural Networks · Physics 2019-02-06 Tatyana Gavrilchenko , Eleni Katifori

Motivated by rolling adhesion of white blood cells in the vasculature, we study how cells move in linear shear flow above a wall to which they can adhere via specific receptor-ligand bonds. Our computer simulations are based on a Langevin…

Cell Behavior · Quantitative Biology 2008-04-30 C. B. Korn , U. S. Schwarz

The dynamics of flow within a material transport network is dependent upon the dynamics of its power source. Responding to a change of these dynamics is critical for the fitness of living flow networks, e.g. the animal vasculature, which…

Fluid Dynamics · Physics 2021-09-29 Sean Fancher , Eleni Katifori

Diverging correlation lengths on either side of the jamming transition are used to formulate a rheological model of granular shear flow, based on the propagation of stress through force chain networks. The model predicts three distinct flow…

Soft Condensed Matter · Physics 2009-11-11 Gregg Lois , Jean M. Carlson

The experimental actualisation of organoids modelling organs from brains to pancreases has revealed that much of the diverse morphologies of organs are emergent properties of simple intercellular "rules" and not the result of top-down…

Tissues and Organs · Quantitative Biology 2019-10-07 Julius B. Kirkegaard , Bjarke F. Nielsen , Ala Trusina , Kim Sneppen

Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…

Quantitative Methods · Quantitative Biology 2017-10-25 Felix Bäuerle , Mirna Kramar , Karen Alim