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How to obtain informative representations of molecules is a crucial prerequisite in AI-driven drug design and discovery. Recent researches abstract molecules as graphs and employ Graph Neural Networks (GNNs) for molecular representation…

Biomolecules · Quantitative Biology 2020-10-30 Yu Rong , Yatao Bian , Tingyang Xu , Weiyang Xie , Ying Wei , Wenbing Huang , Junzhou Huang

We show that viewing graphs as sets of node features and incorporating structural and positional information into a transformer architecture is able to outperform representations learned with classical graph neural networks (GNNs). Our…

Machine Learning · Computer Science 2021-06-11 Grégoire Mialon , Dexiong Chen , Margot Selosse , Julien Mairal

Graph neural networks (GNNs) have achieved remarkable success in various domains, yet they often struggle with domain adaptation due to significant structural distribution shifts and insufficient exploration of transferable patterns. One of…

Machine Learning · Computer Science 2025-10-16 Haoyu Zhang , Yuxuan Cheng , Wenqi Fan , Yulong Chen , Yifan Zhang

Graph Neural Networks (GNNs) have gained momentum in graph representation learning and boosted the state of the art in a variety of areas, such as data mining (\emph{e.g.,} social network analysis and recommender systems), computer vision…

Computer Vision and Pattern Recognition · Computer Science 2024-08-15 Chaoqi Chen , Yushuang Wu , Qiyuan Dai , Hong-Yu Zhou , Mutian Xu , Sibei Yang , Xiaoguang Han , Yizhou Yu

Graph neural networks (GNNs) have emerged as a powerful tool for nonlinear processing of graph signals, exhibiting success in recommender systems, power outage prediction, and motion planning, among others. GNNs consists of a cascade of…

Machine Learning · Computer Science 2020-12-02 Fernando Gama , Joan Bruna , Alejandro Ribeiro

Graph neural networks (GNNs) have attracted much attention because of their excellent performance on tasks such as node classification. However, there is inadequate understanding on how and why GNNs work, especially for node representation…

Machine Learning · Computer Science 2020-06-09 Guoji Fu , Yifan Hou , Jian Zhang , Kaili Ma , Barakeel Fanseu Kamhoua , James Cheng

Graph Neural Networks (GNNs) and Transformers share significant similarities in their encoding strategies for interacting with features from nodes of interest, where Transformers use query-key scores and GNNs use edges. Compared to GNNs,…

Machine Learning · Computer Science 2025-07-08 Jiaxin Qi , Yan Cui , Jinli Ou , Jianqiang Huang , Gaogang Xie

Graph-Level Anomaly Detection (GLAD) aims to distinguish anomalous graphs within a graph dataset. However, current methods are constrained by their receptive fields, struggling to learn global features within the graphs. Moreover, most…

Machine Learning · Computer Science 2024-07-04 Fan Xu , Nan Wang , Hao Wu , Xuezhi Wen , Dalin Zhang , Siyang Lu , Binyong Li , Wei Gong , Hai Wan , Xibin Zhao

Designing spectral convolutional networks is a formidable task in graph learning. In traditional spectral graph neural networks (GNNs), polynomial-based methods are commonly used to design filters via the Laplacian matrix. In practical…

Machine Learning · Computer Science 2024-08-19 Gongpei Zhao , Tao Wang , Yi Jin , Congyan Lang , Yidong Li , Haibin Ling

We introduce Attention Graphs, a new tool for mechanistic interpretability of Graph Neural Networks (GNNs) and Graph Transformers based on the mathematical equivalence between message passing in GNNs and the self-attention mechanism in…

Machine Learning · Computer Science 2025-02-26 Batu El , Deepro Choudhury , Pietro Liò , Chaitanya K. Joshi

Graph Transformers, which incorporate self-attention and positional encoding, have recently emerged as a powerful architecture for various graph learning tasks. Despite their impressive performance, the complex non-convex interactions…

Machine Learning · Computer Science 2024-06-05 Hongkang Li , Meng Wang , Tengfei Ma , Sijia Liu , Zaixi Zhang , Pin-Yu Chen

We show that standard Transformers without graph-specific modifications can lead to promising results in graph learning both in theory and practice. Given a graph, we simply treat all nodes and edges as independent tokens, augment them with…

Machine Learning · Computer Science 2022-10-25 Jinwoo Kim , Tien Dat Nguyen , Seonwoo Min , Sungjun Cho , Moontae Lee , Honglak Lee , Seunghoon Hong

Spectral Graph Neural Networks (GNNs), also referred to as graph filters have gained increasing prevalence for heterophily graphs. Optimal graph filters rely on Laplacian eigendecomposition for Fourier transform. In an attempt to avert the…

Machine Learning · Computer Science 2024-03-06 Keke Huang , Pietro Liò

We propose a graph spectrum-based Gaussian process for prediction of signals defined on nodes of the graph. The model is designed to capture various graph signal structures through a highly adaptive kernel that incorporates a flexible…

Machine Learning · Computer Science 2020-10-29 Yin-Cong Zhi , Yin Cheng Ng , Xiaowen Dong

In this work, we are interested in generalizing convolutional neural networks (CNNs) from low-dimensional regular grids, where image, video and speech are represented, to high-dimensional irregular domains, such as social networks, brain…

Machine Learning · Computer Science 2017-02-07 Michaël Defferrard , Xavier Bresson , Pierre Vandergheynst

Graph Transformers (GTs) have demonstrated a strong capability in modeling graph structures by addressing the intrinsic limitations of graph neural networks (GNNs), such as over-smoothing and over-squashing. Recent studies have proposed…

Machine Learning · Computer Science 2025-02-28 Chaohao Yuan , Kangfei Zhao , Ercan Engin Kuruoglu , Liang Wang , Tingyang Xu , Wenbing Huang , Deli Zhao , Hong Cheng , Yu Rong

This paper introduces a new model to learn graph neural networks equivariant to rotations, translations, reflections and permutations called E(n)-Equivariant Graph Neural Networks (EGNNs). In contrast with existing methods, our work does…

Machine Learning · Computer Science 2022-02-17 Victor Garcia Satorras , Emiel Hoogeboom , Max Welling

Spectral Graph Neural Networks (GNNs) with various graph filters have received extensive affirmation due to their promising performance in graph learning problems. However, it is known that GNNs do not always perform well. Although graph…

Machine Learning · Computer Science 2022-02-18 Zhixian Chen , Tengfei Ma , Yang Wang

Graph Neural Networks (GNNs) have paved the way for being a cornerstone in graph-related learning tasks. Yet, the ability of GNNs to capture structural interactions within graphs remains under-explored. In this work, we address this gap by…

Machine Learning · Computer Science 2025-03-04 Asela Hevapathige , Qing Wang

Spectral Graph Neural Networks (GNNs), alternatively known as graph filters, have gained increasing prevalence for heterophily graphs. Optimal graph filters rely on Laplacian eigendecomposition for Fourier transform. In an attempt to avert…

Machine Learning · Computer Science 2024-05-22 Keke Huang , Yu Guang Wang , Ming Li , and Pietro Liò
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