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Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have…

Computation · Statistics 2018-03-13 Richard J. Boys , Holly F. Ainsworth , Colin S. Gillespie

A model describing the dynamics related to the spreading of non-lethal infectious diseases in a fixed-size population is proposed. The model consists of a non-linear delay-differential equation describing the time evolution of the increment…

Populations and Evolution · Quantitative Biology 2010-10-05 A. Noviello , F. Romeo , R. De Luca

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

Imputation is a popular approach to handling censored, missing, and error-prone covariates -- all coarsened data types for which the true values are unknown. However, there are nuances to imputing these different data types based on the…

Methodology · Statistics 2025-04-29 Sarah C. Lotspeich , Ethan M. Alt

We consider state and parameter estimation for compartmental models having both time-varying and time-invariant parameters. Though the described Bayesian computational framework is general, we look at a specific application to the…

Computational Engineering, Finance, and Science · Computer Science 2023-11-07 Brandon Robinson , Philippe Bisaillon , Jodi D. Edwards , Tetyana Kendzerska , Mohammad Khalil , Dominique Poirel , Abhijit Sarkar

Implicit sampling is a weighted sampling method that is used in data assimilation, where one sequentially updates estimates of the state of a stochastic model based on a stream of noisy or incomplete data. Here we describe how to use…

Numerical Analysis · Mathematics 2016-01-20 Matthias Morzfeld , Xuemin Tu , Jon Wilkening , Alexandre J. Chorin

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

The rise of the World Airline Network over the past century has lead to sharp changes in our notions of `distance' and `closeness' - both in terms of trade and travel, but also (less desirably) with respect to the spread of disease. When…

Physics and Society · Physics 2020-10-13 Alastair Jamieson-Lane , Bernd Blasius

We study the impact of parameter estimation and state measurement errors on a control framework for optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic…

Systems and Control · Electrical Eng. & Systems 2024-08-08 Baike She , Lei Xin , Shreyas Sundaram , Philip E. Paré

The SIR model is used extensively in the field of epidemiology, in particular, for the analysis of communal diseases. One problem with SIR and other existing models is that they are tailored to random or Erdos type networks since they do…

Social and Information Networks · Computer Science 2014-10-22 M. S. S. Khan

Age-dependent dynamics is an important characteristic of many infectious diseases. Age-group epidemic models describe the infection dynamics in different age-groups by allowing to set distinct parameter values for each. However, such models…

Methodology · Statistics 2017-07-17 Rami Yaari , Itai Dattner , Amit Huppert

We study an epidemic propagation between $M$ population centra. The novelty of the model is in analyzing the migration of host (remaining in the same centre) and guest (migrated to another centre) populations separately. Even in the…

Populations and Evolution · Quantitative Biology 2014-01-28 Igor Sazonov , Mark Kelbert , Michael B. Gravenor

In this paper we consider parameter estimation for discretely observed diffusion processes. In particular, we focus on data that are observed at low frequency and methodology that can estimate parameters with uncertainty quantification.…

Computation · Statistics 2026-05-01 Jingning Yao , Ajay Jasra , Sheng Jiang

This paper deals with the stochastic modeling of a class of heterogeneous population in a random environment, called birth-death-swap. In addition to demographic events, swap events, i.e. moves between subgroups, occur in the population.…

Probability · Mathematics 2024-02-28 Sarah Kaakai , Nicole El Karoui

Analyzing the effect of business cycle on rating transitions has been a subject of great interest these last fifteen years, particularly due to the increasing pressure coming from regulators for stress testing. In this paper, we consider…

Probability · Mathematics 2023-06-02 Areski Cousin , Jérôme Lelong , Tom Picard

We present a class of SEIR Markov chain models for infectious diseases observed over discrete time in a random human population living in a closed environment. The population changes over time through random births, deaths, and transitions…

Populations and Evolution · Quantitative Biology 2019-07-30 Divine Wanduku , Chinmoy Rahul

We present a novel approach for learning an HMM whose outputs are distributed according to a parametric family. This is done by {\em decoupling} the learning task into two steps: first estimating the output parameters, and then estimating…

Machine Learning · Computer Science 2013-02-26 Aryeh Kontorovich , Boaz Nadler , Roi Weiss

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

Methodology · Statistics 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

We give new formulas on the total number of born particles in the stable birth-and-assassination process, and prove that it has an heavy-tailed distribution. We also establish that this process is a scaling limit of a process of rumor…

Probability · Mathematics 2008-10-20 Charles Bordenave