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Analytical solutions for time-inhomogeneous linear birth-death processes with immigration are derived. While time-inhomogeneous linear birth-death processes without immigration have been studied by using a generating function approach, the…

Mathematical Physics · Physics 2014-09-05 Jun Ohkubo

This article introduces epidemia, an R package for Bayesian, regression-oriented modeling of infectious diseases. The implemented models define a likelihood for all observed data while also explicitly modeling transmission dynamics: an…

The susceptible-infected-susceptible epidemic model is analyzed through a degree-based mean-field approach. In this work, a mitigation factor is introduced in the probability of finding an infected individual following an edge. This…

Statistical Mechanics · Physics 2025-01-09 K. M. Kim , C. Dias , M. O. Hase

The parameters of many classes of birth-death processes cannot be inferred uniquely from phylogenetic trees: infinitely many parameter combinations yield the same distribution of phylogenetic trees. Here, we show that parameter…

Populations and Evolution · Quantitative Biology 2026-04-21 Tobias Dieselhorst , Tanja Stadler

We study an epidemic model for a constant population by taking into account four compartments of the individuals characterizing their states of health. Each individual is in one of the compartments susceptible (S); incubated - infected yet…

Populations and Evolution · Quantitative Biology 2023-04-20 Teo Granger , Thomas M. Michelitsch , Michael Bestehorn , Alejandro P. Riascos , Bernard A. Collet

Besides mimicking bio-chemical and multi-scale communication mechanisms, molecular communication forms a theoretical framework for virus infection processes. Towards this goal, aerosol and droplet transmission has recently been modeled as a…

Information Theory · Computer Science 2021-01-29 Peter Adam Hoeher , Martin Damrath , Sunasheer Bhattacharjee , Max Schurwanz

We extend our BDI (birth-death-immigration) process based stochastic model of an infectious disease to time-nonhomogeneous cases. First, we discuss the deterministic model, and derive the expected value of the infection process. Then as an…

Methodology · Statistics 2021-01-25 Hisashi Kobayashi

We develop a theory of first passage processes in stochastic non-equilibrium systems of birth-death type using two closely related epidemiological models as examples. Our method employs the probability generating function technique in…

Statistical Mechanics · Physics 2014-08-06 Alex Kamenev , Baruch Meerson

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

Incidence vs Cumulative Cases (ICC) curves are introduced and shown to provide a simple framework for parameter identification in the case of the most elementary epidemiological model, consisting of susceptible, infected, and removed…

Populations and Evolution · Quantitative Biology 2021-04-14 Joceline Lega

Predicting competitive outcomes typically requires fitting dynamical models to data, from which interaction strengths and coexistence indicators such as invasion criteria can be produced. Methods that allow to propagate parameter…

Populations and Evolution · Quantitative Biology 2025-04-10 Matthieu Paquet , Frédéric Barraquand

A birth-death process is a continuous-time Markov chain that counts the number of particles in a system over time. In the general process with $n$ current particles, a new particle is born with instantaneous rate $\lambda_n$ and a particle…

Populations and Evolution · Quantitative Biology 2012-10-11 Forrest W. Crawford , Marc A. Suchard

The isolation-with-migration (IM) model is a common tool to make inferences about the presence of gene flow during speciation, using polymorphism data. However, Becquet and Przeworski (2009) report that the parameter estimates obtained by…

Populations and Evolution · Quantitative Biology 2016-01-15 Rui J. Costa , Hilde Wilkinson-Herbots

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

Computation · Statistics 2022-11-02 Georgios Efstathiadis

Epidemic models often reflect characteristic features of infectious spreading processes by coupled non-linear differential equations considering different states of health (such as Susceptible, Infected, or Recovered). This compartmental…

Physics and Society · Physics 2021-12-01 Vaiva Vasiliauskaite , Nino Antulov-Fantulin , Dirk Helbing

In the face of an infectious disease, a key epidemiological measure is the basic reproduction number, which quantifies the average secondary infections caused by a single case in a susceptible population. In practice, the effective…

Physics and Society · Physics 2025-03-11 Xin-Jian Xu , Song-Jie He , Li-Jie Zhang

This paper is focused on SIS (Susceptible-Infected-Susceptible) epidemic dynamics (also known as the contact process) on populations modelled by homogeneous Poisson point processes of the Euclidean plane, where the infection rate of a…

Probability · Mathematics 2021-08-19 François Baccelli , Nithin Ramesan

We propose a new statistical observation scheme of diffusion processes named convolutional observation, where it is possible to deal with smoother observation than ordinary diffusion processes by considering convolution of diffusion…

Statistics Theory · Mathematics 2020-10-28 Shogo H Nakakita , Masayuki Uchida

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

We consider probabilistic systems with hidden state and unobservable transitions, an extension of Hidden Markov Models (HMMs) that in particular admits unobservable {\epsilon}-transitions (also called null transitions), allowing state…

Machine Learning · Computer Science 2022-05-30 Rebecca Bernemann , Barbara König , Matthias Schaffeld , Torben Weis