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The inference of networks of dependencies by Gaussian Graphical models on high-throughput data is an open issue in modern molecular biology. In this paper we provide a comparative study of three methods to obtain small sample and high…

Molecular Networks · Quantitative Biology 2022-03-02 P. F. Stifanelli , T. M. Creanza , R. Anglani , V. C. Liuzzi , S. Mukherjee , N. Ancona

We consider a problem in parametric estimation: given $n$ samples from an unknown distribution, we want to estimate which distribution, from a given one-parameter family, produced the data. Following Schulman and Vazirani, we evaluate an…

Statistics Theory · Mathematics 2025-07-15 Aaron Abrams , Sandy Ganzell , Henry Landau , Zeph Landau , James Pommersheim , Eric Zaslow

We propose an unconstrained stochastic approximation method of finding the optimal measure change (in an a priori parametric family) for Monte Carlo simulations. We consider different parametric families based on the Girsanov theorem and…

Probability · Mathematics 2018-02-20 Vincent Lemaire , Gilles Pagès

We investigate exponential families of random graph distributions as a framework for systematic quantification of structure in networks. In this paper we restrict ourselves to undirected unlabeled graphs. For these graphs, the counts of…

Disordered Systems and Neural Networks · Physics 2016-04-08 Eckehard Olbrich , Thomas Kahle , Nils Bertschinger , Nihat Ay , Juergen Jost

The expectation-maximization (EM) algorithm is an iterative method for finding maximum likelihood estimates when data are incomplete or are treated as being incomplete. The EM algorithm and its variants are commonly used for parameter…

Computation · Statistics 2013-06-26 Ryan P. Browne , Sanjeena Subedi , Paul McNicholas

We investigate a generic problem of learning pairwise exponential family graphical models with pairwise sufficient statistics defined by a global mapping function, e.g., Mercer kernels. This subclass of pairwise graphical models allow us to…

Machine Learning · Statistics 2013-11-25 Xiao-Tong Yuan , Ping Li , Tong Zhang

Exponential-family Random Graph Models (ERGMs) constitute a large statistical framework for modeling sparse and dense random graphs, short- and long-tailed degree distributions, covariates, and a wide range of complex dependencies. Special…

Methodology · Statistics 2021-05-21 Michael Schweinberger , Pavel N. Krivitsky , Carter T. Butts , Jonathan Stewart

Exponential families form the backbone of modern statistics and machine learning, but textbooks seldom derive them from first principles in an accessible way. Although minimal sufficiency and the principle of maximum entropy, originating in…

Methodology · Statistics 2026-04-27 Korbinian Strimmer

A sequence of random variables is exchangeable if its joint distribution is invariant under variable permutations. We introduce exchangeable variable models (EVMs) as a novel class of probabilistic models whose basic building blocks are…

Machine Learning · Computer Science 2014-05-06 Mathias Niepert , Pedro Domingos

For a random variable $N = 0, 1, 2, \ldots$ we study the following question: When does the sum of $N$ many independent and identically distributed copies of a random variable $X$ have the same law a a nontrivial rescaling of $X$? We show…

Probability · Mathematics 2026-04-03 Andrey Sarantsev

We study the properties of variational Bayes approximations for exponential family models with missing values. It is shown that the iterative algorithm for obtaining the variational Bayesian estimator converges locally to the true value…

Statistics Theory · Mathematics 2012-07-19 Bo Wang , D. Titterington

How many samples are sufficient to guarantee that the eigenvectors and eigenvalues of the sample covariance matrix are close to those of the actual covariance matrix? For a wide family of distributions, including distributions with finite…

Machine Learning · Statistics 2017-02-20 Andreas Loukas

Exponential random graph models are a class of widely used exponential family models for social networks. The topological structure of an observed network is modelled by the relative prevalence of a set of local sub-graph configurations…

Computation · Statistics 2013-01-21 Alberto Caimo , Nial Friel

Spurious association between X and Y may be due to a confounding variable W. Statisticians may adjust for W using a variety of techniques. This paper presents the results of simulations conducted to assess the performance of those…

Methodology · Statistics 2023-10-11 Brian Knaeble

We present a computational approach to solution of the Kiefer-Weiss problem. Algorithms for construction of the optimal sampling plans and evaluation of their performance are proposed. In the particular case of Bernoulli observations, the…

Methodology · Statistics 2021-10-12 Andrey Novikov , Andrei Novikov , Fahil Farkhshatov

We prove the inequality $E[(X/\mu)^k] \le (\frac{k/\mu}{\log(k/\mu+1)})^k \le \exp(k^2/(2\mu))$ for sub-Poissonian random variables, such as Binomially or Poisson distributed random variables with mean $\mu$. The asymptotics $1+O(k^2/\mu)$…

Probability · Mathematics 2021-11-16 Thomas D. Ahle

We consider general Exponential Random Graph Models (ERGMs) where the sufficient statistics are functions of homomorphism counts for a fixed collection of simple graphs $F_k$. Whereas previous work has shown a degeneracy phenomenon in dense…

Probability · Mathematics 2024-04-04 Nicholas A. Cook , Amir Dembo

We propose a K-sparse exhaustive search (ES-K) method and a K-sparse approximate exhaustive search method (AES-K) for selecting variables in linear regression. With these methods, K-sparse combinations of variables are tested exhaustively…

Comparing $K$-sample distributions is a fundamental problem in data science that arises in a wide variety of fields and applications. In this article, we introduce a maximum-of-differences approach to make such comparisons. Specifically, we…

Methodology · Statistics 2026-04-13 Wei Lan , Long Feng , Runze Li , Chih-Ling Tsai

A new approach to adaptive design of clinical trials is proposed in a general multiparameter exponential family setting, based on generalized likelihood ratio statistics and optimal sequential testing theory. These designs are easy to…

Statistics Theory · Mathematics 2011-05-25 Jay Bartroff , Tze Leung Lai