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Single-molecule fluorescence techniques have revolutionized our ability to study proteins. However, the presence of a fluorescent label can alter the protein structure and/or modify its reaction with other species. To avoid the need for a…

Biological Physics · Physics 2022-04-07 Aleksandr Barulin , Prithu Roy , Jean-Benoît Claude , Jérôme Wenger

Current optical detection schemes for single molecules require light absorption, either to produce fluorescence or direct absorption signals. This severely limits the range of molecules that can be detected, because most molecules are…

Chemical Physics · Physics 2012-07-06 Peter Zijlstra , Pedro M. R. Paulo , Michel Orrit

Transient Photoluminescence Microscopy (TPLM) allows for the direct visualization of carrier transport in semiconductor materials with sub nanosecond and few nanometer resolution. The technique is based on measuring changes in the spatial…

In Nature Photonics 5, 166 (2011), we reported on a planar dielectric antenna that achieved 96% efficiency in collecting the photons emitted by a single molecule. In that work the transition dipole moment of the molecule was set…

Quantum Physics · Physics 2016-04-13 Xue-Wen Chen , Stephan Goetzinger , Vahid Sandoghdar

The development of many optical quantum technologies depends on the availability of solid-state single quantum emitters with near-perfect optical coherence. However, a standing issue that limits systematic improvement is the significant…

Lanthanide nanoparticles (LnNPs) feature sharp emission lines together with millisecond emission lifetimes which makes them promising luminescent probes for biosensing and bioimaging. Although LnNPs are gathering a large interest, their…

Single-atom-resolved detection in optical lattices using quantum-gas microscopes has enabled a new generation of experiments in the field of quantum simulation. Fluorescence imaging of individual atoms has so far been achieved for bosonic…

Ensemble averaging experiments may conceal many fundamental molecular interactions. To overcome that, a high-throughput detection of single molecules or colloidal nanodots is crucial for biomedical, nanoelectronic, and solid-state…

Biological Physics · Physics 2019-07-15 Siddharth Ghosh , Narain Karedla , Ingo Gregor

The analysis of entangled atomic ensembles and their application for interferometry beyond the standard quantum limit requires an accurate determination of the number of atoms. We present an accurate fluorescence detection technique for…

Quantum Physics · Physics 2019-12-13 A. Hüper , C. Pür , M. Hetzel , J. Geng , J. Peise , I. Kruse , M. Kristensen , W. Ertmer , J. Arlt , C. Klempt

A nanoparticle detection scheme with single particle resolution is presented. The sensor contains only a taper fiber thus offering the advantages of compactness and installation flexibility. Sensing method is based on monitoring the…

Optics · Physics 2013-05-31 Jiangang Zhu , Sahin Kaya Ozdemir , Lan Yang

We realize a scanning probe microscope using single trapped $^{87}$Rb atoms to measure optical fields with subwavelength spatial resolution. Our microscope operates by detecting fluorescence from a single atom driven by near-resonant light…

Atomic Physics · Physics 2022-03-02 Emma Deist , Justin A. Gerber , Yue-Hui Lu , Johannes Zeiher , Dan M. Stamper-Kurn

Watching the motion of electrons on their natural nanometre length- and femtosecond time scales is a fundamental goal and an open challenge of contemporary ultrafast science. Optical techniques and electron microscopy currently mostly…

Optics · Physics 2018-01-23 Jan Vogelsang , Germann Hergert , Dong Wang , Petra Groß , Christoph Lienau

Fluorescence detection is a commonly used analytical method with the advantages of fast response, good selectivity and low destructiveness. However, fluorescence detection, a single-mode detection method, has some limitations, such as…

Optics · Physics 2024-06-06 Wei Zheng

Plasmonic photoconductive antennas have great promise for increasing responsivity and detection sensitivity of conventional photoconductive detectors in time-domain terahertz imaging and spectroscopy systems. However, operation bandwidth of…

Optics · Physics 2016-12-28 Nezih Tolga Yardimci , Mona Jarrahi

Simultaneous spatio-temporal confinement of energetic electron pulses to femtosecond and nanometer scales is a topic of great interest in the scientific community, given the potential impact of such development on a wide spectrum of…

FRET-based approaches are a unique tool for sensing the immediate surroundings and interactions of (bio)molecules. FRET imaging and FLIM (Fluorescence Lifetime Imaging Microscopy) enable the visualization of the spatial distribution of…

Plasmonic nanoparticles resonantly couple to and confine light below the diffraction limit. This mechanism has enabled a modern renaissance in optical materials, with potential applications ranging from sensing and circuitry to renewable…

While sensing in high temporal resolution is necessary for wide range of application, it is still limited nowadays due to cameras sampling rate. In this work we try to increase the temporal resolution beyond the Nyquist frequency, which is…

Signal Processing · Electrical Eng. & Systems 2022-11-28 Khen Cohen , Dan Raviv , David Mendlovic

Attosecond science has demonstrated that electrons can be controlled on the sub-cycle time scale of an optical wave, paving the way toward optical frequency electronics. Using controlled few-cycle optical waveforms, the study of sub-cycle…

Nanoantennas capable of large fluorescence enhancement with minimal absorption are crucial for future optical technologies from single-photon sources to biosensing. Efficient dielectric nanoantennas have been designed, however, evaluating…