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In Fourier-domain optical coherence tomography (OCT), the finite bandwidth of the acquisition electronics constrains the depth range and speed of the system. Circular-ranging (CR) OCT methods use optical-domain compression to surpass this…

Applied Physics · Physics 2019-11-01 Norman Lippok , Brett E. Bouma , Benjamin J. Vakoc

The Coherent Multiplex is formalized and validated as a scalable, real-time system for identifying, analyzing, and visualizing coherence among multiple time series. Its architecture comprises a fast spectral similarity layer based on cosine…

Signal Processing · Electrical Eng. & Systems 2025-08-28 Noah Shore

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…

Optics · Physics 2009-11-11 C. Vinegoni , T. Ralston , W. Tan , W. Luo , D. L. Marks , S. A. Boppart

Optical computing offers ultrafast, energy-efficient alternatives to conventional digital processors, yet most implementations remain confined to single-channel processing, severely underutilizing light's information capacity. Here we…

Optics · Physics 2026-01-13 Fatma Nur Kılınç , Uğur Teğin

Current spectroscopic optical coherence tomography (OCT) methods rely on a posteriori numerical calculation. We present an alternative for accessing optically the spectroscopic information in OCT, i.e. without any post-processing, by using…

Orthogonal time frequency space (OTFS) is a 2-dimensional (2D) modulation technique designed in the delay-Doppler domain. A key premise behind OTFS is the transformation of a time varying multipath channel into an almost non-fading 2D…

Information Theory · Computer Science 2019-04-02 G. D. Surabhi , Rose Mary Augustine , A. Chockalingam

Quantum techniques can be used to enhance the signal-to-noise ratio in optical imaging. Leveraging the latest advances in single photon avalanche diode array cameras and multi-photon detection techniques, here we introduce a super-sensitive…

High-numerical-aperture optical coherence tomography (OCT) enables sub-cellular imaging but faces a trade-off between lateral resolution and depth of focus. Computational refocusing can correct defocus in Fourier-domain OCT, yet its…

Optics · Physics 2026-05-22 Yue Zhu , Shuichi Makita , Naoki Fukutake , Yoshiaki Yasuno

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

Computer Vision and Pattern Recognition · Computer Science 2012-05-03 Yankui Sun , Tian Zhang

Optical Coherence Tomography (OCT) is a key 3D imaging technology that provides micron scale depth resolution for bio-imaging. This resolution substantially surpasses what it typically achieved in Light Detection and Ranging (LiDAR) which…

Optics · Physics 2022-07-27 Robbie Murray , Ashley Lyons

Inhomogeneities in the refractive index of a biological sample can introduce phase aberrationsin microscopy systems, severely impairing the quality of images. Adaptive optics can be employed to correct for phase aberrations and improve…

In vivo application of dynamic optical coherence tomography (DOCT) is hindered by bulk motion of the sample. We demonstrate DOCT imaging of \invivo human skin by adopting a sample-fixation attachment to suppress bulk motion and a subsequent…

This paper reports on advances in optical coherence tomography (OCT) for application in dermatology. Full-field OCT is a particular approach of OCT based on white-light interference microscopy. FF-OCT produces en face tomographic images by…

Medical Physics · Physics 2018-04-06 Olivier Levecq , Arthur Davis , Hicham Azimani , David Siret , Jean-Luc Perrot , Arnaud Dubois

Multispectral imaging has been used for numerous applications in e.g., environmental monitoring, aerospace, defense, and biomedicine. Here, we present a diffractive optical network-based multispectral imaging system trained using deep…

Optics · Physics 2023-04-07 Deniz Mengu , Anika Tabassum , Mona Jarrahi , Aydogan Ozcan

Convolutional neural networks are paramount in image and signal processing including the relevant classification and training tasks alike and constitute for the majority of machine learning compute demand today. With convolution operations…

Orbital angular momentum (OAM) multiplexing offers a promising approach to high-capacity optical communication by harnessing the orthogonality of vortex beams. However, its practical deployment is severely limited in real-world settings…

Multispectral imaging plays an important role in many applications from astronomical imaging, earth observation to biomedical imaging. However, the current technologies are complex with multiple alignment-sensitive components, predetermined…

Optics · Physics 2021-09-17 Sujit Kumar Sahoo , Dongliang Tang , Cuong Dang

Frame rate is a crucial consideration in cardiac ultrasound imaging and 3D sonography. Several methods have been proposed in the medical ultrasound literature aiming at accelerating the image acquisition. In this paper, we consider one such…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Sanketh Vedula , Ortal Senouf , Grigoriy Zurakhov , Alex M. Bronstein , Michael Zibulevsky , Oleg Michailovich , Dan Adam , Diana Gaitini

Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a…