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Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Anomaly detection is the process of identifying atypical data samples that significantly deviate from the majority of the dataset. In the realm of clinical screening and diagnosis, detecting abnormalities in medical images holds great…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Xianyao Hu , Congming Jin

Recent progress in generative models has made it easier for a wide audience to edit and create image content, raising concerns about the proliferation of deepfakes, especially in healthcare. Despite the availability of numerous techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Fred Grabovski , Lior Yasur , Guy Amit , Yisroel Mirsky

Contrastive Analysis (CA) detects anomalies by contrasting patterns unique to a target group (e.g., unhealthy subjects) from those in a background group (e.g., healthy subjects). In the context of brain MRIs, existing CA approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Cristiano Patrício , Carlo Alberto Barbano , Attilio Fiandrotti , Riccardo Renzulli , Marco Grangetto , Luis F. Teixeira , João C. Neves

Diffusion models have found valuable applications in anomaly detection by capturing the nominal data distribution and identifying anomalies via reconstruction. Despite their merits, they struggle to localize anomalies of varying scales,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Justin Tebbe , Jawad Tayyub

Reconstruction-based approaches have achieved remarkable outcomes in anomaly detection. The exceptional image reconstruction capabilities of recently popular diffusion models have sparked research efforts to utilize them for enhanced…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Haoyang He , Jiangning Zhang , Hongxu Chen , Xuhai Chen , Zhishan Li , Xu Chen , Yabiao Wang , Chengjie Wang , Lei Xie

Anomaly detection is a critical task in computer vision with profound implications for medical imaging, where identifying pathologies early can directly impact patient outcomes. While recent unsupervised anomaly detection approaches show…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Le Dong , Qinzhong Tan , Chunlei Li , Jingliang Hu , Yilei Shi , Weisheng Dong , Xiao Xiang Zhu , Lichao Mou

Difference image analysis (DIA) is a powerful tool for studying time-variable phenomena, and has been used by many time-domain surveys. Most DIA algorithms involve matching the spatially-varying PSF shape between science and template…

Ultrasound imaging, despite its widespread use in medicine, often suffers from various sources of noise and artifacts that impact the signal-to-noise ratio and overall image quality. Enhancing ultrasound images requires a delicate balance…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Yuxin Zhang , Clément Huneau , Jérôme Idier , Diana Mateus

Anomaly detection, the technique of identifying abnormal samples using only normal samples, has attracted widespread interest in industry. Existing one-model-per-category methods often struggle with limited generalization capabilities due…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Jiawei Zhan , Jinxiang Lai , Bin-Bin Gao , Jun Liu , Xiaochen Chen , Chengjie Wang

Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

Diffusion models have shown to be strong representation learners, showcasing state-of-the-art performance across multiple domains. Aside from accelerated sampling, DDIM also enables the inversion of real images back to their latent codes. A…

Artificial Intelligence · Computer Science 2025-10-02 Seunghoo Hong , Geonho Son , Juhun Lee , Simon S. Woo

Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Ran Gu , Guotai Wang , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Yinan Chen , Wenjun Liao , Shichuan Zhang , Kang Li , Dimitris N. Metaxas , Shaoting Zhang

Removing degradation from document images not only improves their visual quality and readability, but also enhances the performance of numerous automated document analysis and recognition tasks. However, existing regression-based methods…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Zongyuan Yang , Baolin Liu , Yongping Xiong , Lan Yi , Guibin Wu , Xiaojun Tang , Ziqi Liu , Junjie Zhou , Xing Zhang

Image enhancement improves visual quality and helps reveal details that are hard to see in the original image. In medical imaging, it can support clinical decision-making, but current models often over-edit. This can distort organs, create…

Many self-supervised denoising approaches have been proposed in recent years. However, these methods tend to overly smooth images, resulting in the loss of fine structures that are essential for medical applications. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2025-04-02 Basar Demir , Yikang Liu , Xiao Chen , Eric Z. Chen , Lin Zhao , Boris Mailhe , Terrence Chen , Shanhui Sun

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

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