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The vast applications of deep generative models are anchored in three core capabilities -- generating new instances, reconstructing inputs, and learning compact representations -- across various data types, such as discrete text/protein…

Machine Learning · Computer Science 2024-06-06 Guangyi Liu , Yu Wang , Zeyu Feng , Qiyu Wu , Liping Tang , Yuan Gao , Zhen Li , Shuguang Cui , Julian McAuley , Zichao Yang , Eric P. Xing , Zhiting Hu

We conduct a scoping review of existing approaches for synthetic EHR data generation, and benchmark major methods with proposed open-source software to offer recommendations for practitioners. We search three academic databases for our…

Machine Learning · Computer Science 2025-06-05 Xingran Chen , Zhenke Wu , Xu Shi , Hyunghoon Cho , Bhramar Mukherjee

Synthetic tabular data enables sharing and analysis of sensitive records, but its practical deployment requires balancing distributional fidelity, downstream utility, and privacy protection. We study a simple, model agnostic post processing…

Machine Learning · Computer Science 2026-02-09 David Yavo , Richard Khoury , Christophe Pere , Sadoune Ait Kaci Azzou

The ability to train generative models that produce realistic, safe and useful tabular data is essential for data privacy, imputation, oversampling, explainability or simulation. However, generating tabular data is not straightforward due…

Machine Learning · Computer Science 2025-09-18 G. Charbel N. Kindji , Lina Maria Rojas-Barahona , Elisa Fromont , Tanguy Urvoy

Training data has been proven to be one of the most critical components in training generative AI. However, obtaining high-quality data remains challenging, with data privacy issues presenting a significant hurdle. To address the need for…

Computation and Language · Computer Science 2025-06-18 Jia-Chen Zhang , Zheng Zhou , Yu-Jie Xiong , Chun-Ming Xia , Fei Dai

Synthetic data has recently reached a level of visual fidelity that makes it nearly indistinguishable from real data, offering great promise for privacy-preserving data sharing in medical imaging. However, fully synthetic datasets still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Mischa Dombrowski , Bernhard Kainz

As deep learning technologies advance, increasingly more data is necessary to generate general and robust models for various tasks. In the medical domain, however, large-scale and multi-parties data training and analyses are infeasible due…

Machine Learning · Computer Science 2020-12-17 Qi Chang , Zhennan Yan , Lohendran Baskaran , Hui Qu , Yikai Zhang , Tong Zhang , Shaoting Zhang , Dimitris N. Metaxas

Accessing longitudinal multimodal Electronic Healthcare Records (EHRs) is challenging due to privacy concerns, which hinders the use of ML for healthcare applications. Synthetic EHRs generation bypasses the need to share sensitive real…

Computation and Language · Computer Science 2022-11-04 Zifeng Wang , Jimeng Sun

Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating…

Machine Learning · Computer Science 2019-11-28 Saloni Dash , Ritik Dutta , Isabelle Guyon , Adrien Pavao , Andrew Yale , Kristin P. Bennett

While many deep learning models trained on private datasets have been deployed in various practical tasks, they may pose a privacy leakage risk as attackers could recover informative data or label knowledge from models. In this work, we…

Machine Learning · Computer Science 2026-01-28 Bochao Liu , Shiming Ge , Pengju Wang , Shikun Li , Tongliang Liu

Diffusion-based tabular data synthesis models have yielded promising results. However, when the data dimensionality increases, existing models tend to degenerate and may perform even worse than simpler, non-diffusion-based models. This is…

Machine Learning · Computer Science 2025-11-12 Zuqing Li , Junhao Gan , Jianzhong Qi

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

The widespread adoption of electronic health records (EHRs) and subsequent increased availability of longitudinal healthcare data has led to significant advances in our understanding of health and disease with direct and immediate impact on…

Machine Learning · Computer Science 2022-01-21 Simon Bing , Andrea Dittadi , Stefan Bauer , Patrick Schwab

An Electronic Health Record (EHR) is an electronic database used by healthcare providers to store patients' medical records which may include diagnoses, treatments, costs, and other personal information. Machine learning (ML) algorithms can…

Machine Learning · Computer Science 2024-06-25 Naif A. Ganadily , Han J. Xia

Generative Adversarial Network (GAN) and its variants have recently attracted intensive research interests due to their elegant theoretical foundation and excellent empirical performance as generative models. These tools provide a promising…

Machine Learning · Computer Science 2018-02-20 Liyang Xie , Kaixiang Lin , Shu Wang , Fei Wang , Jiayu Zhou

Electronic health records (EHRs) offer great promises for advancing precision medicine and, at the same time, present significant analytical challenges. Particularly, it is often the case that patient-level data in EHRs cannot be shared…

Methodology · Statistics 2022-07-04 Changgee Chang , Zhiqi Bu , Qi Long

Privacy concerns have led to a surge in the creation of synthetic datasets, with diffusion models emerging as a promising avenue. Although prior studies have performed empirical evaluations on these models, there has been a gap in providing…

Machine Learning · Computer Science 2024-06-04 Rongzhe Wei , Eleonora Kreačić , Haoyu Wang , Haoteng Yin , Eli Chien , Vamsi K. Potluru , Pan Li

Utility and privacy are two crucial measurements of the quality of synthetic tabular data. While significant advancements have been made in privacy measures, generating synthetic samples with high utility remains challenging. To enhance the…

Machine Learning · Computer Science 2024-03-28 Oriel Perets , Nadav Rappoport

Tabular data typically contains private and important information; thus, precautions must be taken before they are shared with others. Although several methods (e.g., differential privacy and k-anonymity) have been proposed to prevent…

Cryptography and Security · Computer Science 2022-08-26 Jihyeon Hyeong , Jayoung Kim , Noseong Park , Sushil Jajodia

Deep generative models have made rapid progress in image, text, audio, and video generation, and are increasingly being applied to structured records. For tabular data, however, generative modeling remains difficult: a dataset may contain…

Machine Learning · Computer Science 2026-05-25 Zhong Li , Qi Huang , Lincen Yang , Jiayang Shi , Zhao Yang , Niki van Stein , Thomas Bäck , Matthijs van Leeuwen