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Background and Objective:Computer-aided diagnosis (CAD) systems promote diagnosis effectiveness and alleviate pressure of radiologists. A CAD system for lung cancer diagnosis includes nodule candidate detection and nodule malignancy…

Image and Video Processing · Electrical Eng. & Systems 2022-01-17 Shaohua Zheng , Zhiqiang Shen , Chenhao Peia , Wangbin Ding , Haojin Lin , Jiepeng Zheng , Lin Pan , Bin Zheng , Liqin Huang

Deep neural networks have achieved remarkable success in various challenging tasks. However, the black-box nature of such networks is not acceptable to critical applications, such as healthcare. In particular, the existence of adversarial…

Machine Learning · Computer Science 2019-09-12 Shaeke Salman , Seyedeh Neelufar Payrovnaziri , Xiuwen Liu , Pablo Rengifo-Moreno , Zhe He

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

Concept Bottleneck Models (CBMs) have recently been proposed to address the 'black-box' problem of deep neural networks, by first mapping images to a human-understandable concept space and then linearly combining concepts for…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Sukrut Rao , Sweta Mahajan , Moritz Böhle , Bernt Schiele

Deep learning algorithms have recently gained significant attention due to their impressive performance. However, their high complexity and un-interpretable mode of operation hinders their confident deployment in real-world safety-critical…

Machine Learning · Computer Science 2024-06-28 Konstantinos P. Panousis , Dino Ienco , Diego Marcos

Concept Bottleneck Model (CBM) is a methods for explaining neural networks. In CBM, concepts which correspond to reasons of outputs are inserted in the last intermediate layer as observed values. It is expected that we can interpret the…

Machine Learning · Statistics 2024-03-15 Naoki Hayashi , Yoshihide Sawada

The proliferation of early diagnostic technologies, including self-monitoring systems and wearables, coupled with the application of these technologies on large segments of healthy populations may significantly aggravate the problem of…

Machine Learning · Computer Science 2021-07-23 Anna Fedyukova , Douglas Pires , Daniel Capurro

In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…

Machine Learning · Computer Science 2016-09-14 Cheng Zhang , Hedvig Kjellstrom , Carl Henrik Ek , Bo C. Bertilson

Continual learning (CL) aims to enable learning systems to acquire new knowledge constantly without forgetting previously learned information. CL faces the challenge of mitigating catastrophic forgetting while maintaining interpretability…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Lu Yu , Haoyu Han , Zhe Tao , Hantao Yao , Changsheng Xu

Proactive analysis of patient pathways helps healthcare providers anticipate treatment-related risks, identify outcomes, and allocate resources. Machine learning (ML) can leverage a patient's complete health history to make informed…

Machine Learning · Computer Science 2024-05-24 Sandra Zilker , Sven Weinzierl , Mathias Kraus , Patrick Zschech , Martin Matzner

Concept Bottleneck Models (CBMs) offer inherent interpretability by initially translating images into human-comprehensible concepts, followed by a linear combination of these concepts for classification. However, the annotation of concepts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Hangzhou He , Lei Zhu , Xinliang Zhang , Shuang Zeng , Qian Chen , Yanye Lu

Endometriosis is a non-malignant disorder that affects 176 million women globally. Diagnostic delays result in severe dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. Therefore, there is a significant need to diagnose…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Adrian Balica , Jennifer Dai , Kayla Piiwaa , Xiao Qi , Ashlee N. Green , Nancy Phillips , Susan Egan , Ilker Hacihaliloglu

Concept bottleneck models (CBMs) are inherently interpretable and intervenable neural network models, which explain their final label prediction by the intermediate prediction of high-level semantic concepts. However, they require target…

Machine Learning · Computer Science 2026-04-06 Shin'ya Yamaguchi , Kosuke Nishida , Daiki Chijiwa , Yasutoshi Ida

Deep Neural Networks (DNNs) are widely used for decision making in a myriad of critical applications, ranging from medical to societal and even judicial. Given the importance of these decisions, it is crucial for us to be able to interpret…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Teddy Koker , Fatemehsadat Mireshghallah , Tom Titcombe , Georgios Kaissis

Deep learning models have shown promise in lung pathology detection from chest X-rays, but widespread clinical adoption remains limited due to opaque model decision-making. In prior work, we introduced ClinicXAI, a human-centric,…

Artificial Intelligence · Computer Science 2026-04-17 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…

Machine Learning · Computer Science 2016-12-06 Cheng Zhang , Hedvig Kjellstrom , Bo C. Bertilson

Hybrid methods have been shown to outperform pure statistical and pure deep learning methods at both forecasting tasks, and at quantifying the uncertainty associated with those forecasts (prediction intervals). One example is Multivariate…

Machine Learning · Computer Science 2022-02-28 Thabang Mathonsi , Terence L van Zyl

Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Ulzee An , Khader Shameer , Lakshmi Subramanian

As the global population ages, the incidence of Chronic Kidney Disease (CKD) is rising. CKD often remains asymptomatic until advanced stages, which significantly burdens both the healthcare system and patient quality of life. This research…

Artificial Intelligence · Computer Science 2024-04-18 Nantika Nguycharoen

Diabetes encompasses a complex landscape of glycemic control that varies widely among individuals. However, current methods do not faithfully capture this variability at the meal level. On the one hand, expert-crafted features lack the…

Machine Learning · Computer Science 2023-12-07 Ke Alexander Wang , Emily B. Fox