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Graph Neural Networks (GNNs) have been widely employed for feature representation learning in molecular graphs. Therefore, it is crucial to enhance the expressiveness of feature representation to ensure the effectiveness of GNNs. However, a…

Machine Learning · Computer Science 2024-09-16 Chengyu Yao , Hong Huang , Hang Gao , Fengge Wu , Haiming Chen , Junsuo Zhao

Molecular representation learning is crucial for the problem of molecular property prediction, where graph neural networks (GNNs) serve as an effective solution due to their structure modeling capabilities. Since labeled data is often…

Machine Learning · Computer Science 2023-09-26 Cameron Diao , Kaixiong Zhou , Zirui Liu , Xiao Huang , Xia Hu

Pretrained Graph Neural Networks have been widely adopted for various molecular property prediction tasks. Despite their ability to encode structural and relational features of molecules, traditional fine-tuning of such pretrained GNNs on…

Machine Learning · Computer Science 2024-01-30 Vishal Dey , Xia Ning

Graph neural networks (GNN) have achieved remarkable success in a wide range of tasks by encoding features combined with topology to create effective representations. However, the fundamental problem of understanding and analyzing how graph…

Machine Learning · Computer Science 2024-04-12 Kailong Wu , Yule Xie , Jiaxin Ding , Yuxiang Ren , Luoyi Fu , Xinbing Wang , Chenghu Zhou

Graph Neural Networks (GNNs) have emerged as powerful tools for learning over graph-structured data, yet recent studies have shown that their performance gains are beginning to plateau. In many cases, well-established models such as GCN and…

Machine Learning · Computer Science 2026-02-13 Mohit Meena , Yash Punjabi , Abhishek A , Vishal Sharma , Mahesh Chandran

Graph Neural Networks (GNNs) have revolutionized the field of graph learning by learning expressive graph representations from massive graph data. As a common pattern to train powerful GNNs, the "pre-training, adaptation" scheme first…

Machine Learning · Computer Science 2025-10-28 Xingbo Fu , Zhenyu Lei , Zihan Chen , Binchi Zhang , Chuxu Zhang , Jundong Li

In colored graphs, node classes are often associated with either their neighbors class or with information not incorporated in the graph associated with each node. We here propose that node classes are also associated with topological…

Social and Information Networks · Computer Science 2019-11-19 Roy Abel , Idan Benami , Yoram Louzoun

Graph Neural Networks (GNNs) often struggle in preserving high-frequency components of nodal signals when dealing with directed graphs. Such components are crucial for modeling flow dynamics, without which a traditional GNN tends to treat a…

Machine Learning · Computer Science 2025-06-09 Haoyang Jiang , Jindong Wang , Xingquan Zhu , Yi He

Constructing appropriate representations of molecules lies at the core of numerous tasks such as material science, chemistry and drug designs. Recent researches abstract molecules as attributed graphs and employ graph neural networks (GNN)…

Machine Learning · Computer Science 2021-07-29 Jianwen Chen , Shuangjia Zheng , Ying Song , Jiahua Rao , Yuedong Yang

Molecular representation learning methods typically tokenize molecules as individual atoms or use rigid, rule-based fragment decompositions, limiting their ability to capture meaningful chemical substructure context. We introduce…

Machine Learning · Computer Science 2026-05-26 Ankur Samanta , Rohan Gupta , Aditi Misra , Christian McIntosh Clarke , Jayakumar Rajadas

Nuclei classification is a critical step in computer-aided diagnosis with histopathology images. In the past, various methods have employed graph neural networks (GNN) to analyze cell graphs that model inter-cell relationships by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Wei Lou , Guanbin Li , Xiang Wan , Haofeng Li

In recent years, using a self-supervised learning framework to learn the general characteristics of graphs has been considered a promising paradigm for graph representation learning. The core of self-supervised learning strategies for graph…

Machine Learning · Computer Science 2022-12-09 Jiawei Zhu , Mei Hong , Ronghua Du , Haifeng Li

Recently, graph-based models designed for downstream tasks have significantly advanced research on graph neural networks (GNNs). GNN baselines based on neural message-passing mechanisms such as GCN and GAT perform worse as the network…

Machine Learning · Computer Science 2023-01-26 Jiayuan Chen , Xiang Zhang , Yinfei Xu , Tianli Zhao , Renjie Xie , Wei Xu

Graph neural networks (GNNs), which propagate the node features through the edges and learn how to transform the aggregated features under label supervision, have achieved great success in supervised feature extraction for both node-level…

Machine Learning · Statistics 2022-11-01 Yilin He , Chaojie Wang , Hao Zhang , Bo Chen , Mingyuan Zhou

We study a new paradigm of knowledge transfer that aims at encoding graph topological information into graph neural networks (GNNs) by distilling knowledge from a teacher GNN model trained on a complete graph to a student GNN model…

Machine Learning · Computer Science 2023-01-18 Chenxiao Yang , Qitian Wu , Junchi Yan

Molecular property is usually observed with a limited number of samples, and researchers have considered property prediction as a few-shot problem. One important fact that has been ignored by prior works is that each molecule can be…

Machine Learning · Computer Science 2023-06-30 Xiang Zhuang , Qiang Zhang , Bin Wu , Keyan Ding , Yin Fang , Huajun Chen

Graph Neural Networks (GNNs) have emerged as a powerful tool to capture intricate network patterns, achieving success across different domains. However, existing GNNs require careful domain-specific architecture designs and training from…

Machine Learning · Computer Science 2025-05-30 Jingzhe Liu , Haitao Mao , Zhikai Chen , Bingheng Li , Wenqi Fan , Mingxuan Ju , Tong Zhao , Neil Shah , Jiliang Tang

In recent years, graph neural networks (GNNs) have emerged as a potent tool for learning on graph-structured data and won fruitful successes in varied fields. The majority of GNNs follow the message-passing paradigm, where representations…

Machine Learning · Computer Science 2024-08-30 Yurui Lai , Xiaoyang Lin , Renchi Yang , Hongtao Wang

Graph Neural Networks (GNNs) have shown great promise in learning node embeddings for link prediction (LP). While numerous studies aim to improve the overall LP performance of GNNs, none have explored its varying performance across…

Machine Learning · Computer Science 2023-10-10 Yu Wang , Tong Zhao , Yuying Zhao , Yunchao Liu , Xueqi Cheng , Neil Shah , Tyler Derr

Social networks crawling is in the focus of active research the last years. One of the challenging task is to collect target nodes in an initially unknown graph given a budget of crawling steps. Predicting a node property based on its…

Social and Information Networks · Computer Science 2024-03-22 Kirill Lukyanov , Mikhail Drobyshevskiy , Danil Shaikhelislamov , Denis Turdakov