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We introduce the concept of epidemic-fitted wavelets which comprise, in particular, as special cases the number $I(t)$ of infectious individuals at time $t$ in classical SIR models and their derivatives. We present a novel method for…

Computational multi-scale pandemic modelling remains a major and timely challenge. Here we identify specific requirements for a new class of models simulating pandemics across three scales: (1) pathogen evolution, often punctuated by the…

Populations and Evolution · Quantitative Biology 2025-08-04 Quang Dang Nguyen , Sheryl L. Chang , Carl J. E. Suster , Rebecca J. Rockett , Vitali Sintchenko , Tania C. Sorrell , Mikhail Prokopenko

It is of vital importance to understand and track the dynamics of rapidly unfolding epidemics. The health and economic consequences of the current COVID-19 pandemic provide a poignant case. Here we point out that since they are based on…

Populations and Evolution · Quantitative Biology 2020-04-28 Z. Fodor , S. D. Katz , T. G. Kovacs

The ubiquity of oscillations in epidemics presents a long standing challenge for the formulation of epidemic models. Whether they are external and seasonally driven, or arise from the intrinsic dynamics is an open problem. It is known that…

Populations and Evolution · Quantitative Biology 2011-09-06 S. Goncalves , G. Abramson , M. F. C. Gomes

Students develop and test simple models of the spread of COVID-19. Microsoft Excel is used as the modeling platform because it's non-threatening to students and because it's widely available. Students develop finite difference models and…

Physics Education · Physics 2021-12-14 Peter Hugo Nelson

We introduce a digital twin of the classical compartmental SIR (Susceptible, Infected, Recovered) epidemic model and study the interrelation between the digital twin and the system. In doing so, we use Stieltjes derivatives to feed the data…

Other Quantitative Biology · Quantitative Biology 2021-05-06 Iván Area , F. J. Fernández , Juan J. Nieto , F. Adrián F. Tojo

The present paper introduces a data-driven framework for describing the time-varying nature of an SIRD model in the context of COVID-19. By embedding a rolling regression in a mixed integer bilevel nonlinear programming problem, our aim is…

Populations and Evolution · Quantitative Biology 2021-03-04 Javier Rubio-Herrero , Yuchen Wang

This research presents an advanced fractional-order compartmental model designed to delve into the complexities of COVID-19 transmission dynamics, specifically accounting for the influence of environmental pathogens on disease spread. By…

Populations and Evolution · Quantitative Biology 2024-07-09 Moein Khalighi , Faïçal Ndaïrou , Leo Lahti

We study evolution equations of drift-diffusion type when various parameters are random. Motivated by applications in pedestrian dynamics, we focus on the case when the total mass is, due to boundary or reaction terms, not conserved. After…

Probability · Mathematics 2021-07-28 Greta Marino , Jan-Frederik Pietschmann , Alois Pichler

Population-wide vaccination is critical for containing the SARS-CoV-2 (Covid-19) pandemic when combined with restrictive and prevention measures. In this study, we introduce SAIVR, a mathematical model able to forecast the Covid-19 epidemic…

Populations and Evolution · Quantitative Biology 2022-01-19 Mattia Angeli , Georgios Neofotistos , Marios Mattheakis , Efthimios Kaxiras

A model of reactive social distancing in epidemics is proposed, in which the infection rate changes with the number infected. The final-size equation for the total number that the epidemic will infect can be derived analytically, as can the…

Populations and Evolution · Quantitative Biology 2020-03-19 Rose Baker

The COVID-19 pandemic has presented unprecedented challenges worldwide, necessitating effective modelling approaches to understand and control its transmission dynamics. In this study, we propose a novel approach that integrates…

Populations and Evolution · Quantitative Biology 2025-01-14 Moein Khalighi , Leo Lahti , Faïçal Ndaïrou , Peter Rashkov , Delfim F. M. Torres

The unprecedented coronavirus disease 2019 (COVID-19) pandemic is still a worldwide threat to human life since its invasion into the daily lives of the public in the first several months of 2020. Predicting the size of confirmed cases is…

Applications · Statistics 2020-12-02 Xinyu Wang , Lu Yang , Hong Zhang , Zhouwang Yang , Catherine Liu

Diffusion models have emerged as powerful generative frameworks by progressively adding noise to data through a forward process and then reversing this process to generate realistic samples. While these models have achieved strong…

Machine Learning · Computer Science 2025-03-04 Xingzhuo Guo , Yu Zhang , Baixu Chen , Haoran Xu , Jianmin Wang , Mingsheng Long

Compartmental models are a tool commonly used in epidemiology for the mathematical modelling of the spread of infectious diseases, with their most popular representative being the Susceptible-Infected-Removed (SIR) model and its…

Machine Learning · Computer Science 2022-12-19 Lorenz Kummer , Kevin Sidak

We present a phenomenological procedure of dealing with the COVID--19 data provided by government health agencies of eleven different countries. Instead of using the (exact or approximate) solutions to the SIR (or other) model(s) to fit the…

Physics and Society · Physics 2020-12-02 Sergio A. Hojman , Felipe A. Asenjo

We show that the mean field equations for the SIR epidemic can be exactly solved for a network with arbitrary degree distribution. Our exact solution consists of reducing the dynamics to a lone first order differential equation, which has a…

Physics and Society · Physics 2012-06-28 Andrew Lucas

Epidemic models currently play a central role in our attempts to understand and control infectious diseases. Here, we derive a model for the diffusion limit of stochastic susceptible-infectious-removed (SIR) epidemic dynamics on a…

Populations and Evolution · Quantitative Biology 2013-09-30 Matthew Graham , Thomas House

We investigate an epidemic model based on Bailey's continuous differential system. In the continuous time domain, we extend the classical model to time-dependent coefficients and present an alternative solution method to Gleissner's…

Classical Analysis and ODEs · Mathematics 2019-01-01 Martin Bohner , Sabrina Streipert , Delfim F. M. Torres

When fitting a multi-parameter model to a data set, computer algorithms may suggest that a range of parameters provide equally reasonable fits, making the parameter estimation difficult. Here, we prove this fact for an SIR model. We say a…

Populations and Evolution · Quantitative Biology 2024-04-08 B Shayak , Sana Jahedi , James A Yorke
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