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Deep generative models are increasingly becoming integral parts of the in silico molecule design pipeline and have dual goals of learning the chemical and structural features that render candidate molecules viable while also being flexible…

Biomolecules · Quantitative Biology 2021-06-08 Yair Schiff , Vijil Chenthamarakshan , Karthikeyan Natesan Ramamurthy , Payel Das

In this paper, a systematic approach is developed to embed the dynamical description of a nonlinear system into a linear parameter-varying (LPV) system representation. Initially, the nonlinear functions in the model representation are…

Systems and Control · Electrical Eng. & Systems 2020-11-09 Arash Sadeghzadeh , Roland Toth

We developed a single factor model with measure-specific sample weights for multivariate data with multiple observed indicators clustered within a higher level subject. The factor is therefore a latent variable shared by multiple indicators…

Methodology · Statistics 2019-10-22 Chengan Du , Shu-Xia Li , Zhenqiu Lin , Haiqun Lin

Latent variable models are powerful statistical tools that can uncover relevant variation between patients or cells, by inferring unobserved hidden states from observable high-dimensional data. A major shortcoming of current methods,…

Machine Learning · Statistics 2022-04-12 Arber Qoku , Florian Buettner

Temperature-induced phase transition in BaTiO3 has been explored using the machine learning analysis of domain morphologies visualized via variable-temperature scanning transmission electron microscopy (STEM) imaging data. This approach is…

Materials Science · Physics 2020-11-20 Mani Valleti , Reinis Ignatans , Sergei V. Kalinin , Vasiliki Tileli

Structural monitoring for complex built environments often suffers from mismatch between design, laboratory testing, and actual built parameters. Additionally, real-world structural identification problems encounter many challenges. For…

Machine Learning · Computer Science 2022-08-29 Xuyang Li , Hamed Bolandi , Talal Salem , Nizar Lajnef , Vishnu Naresh Boddeti

Cognitive diagnostic assessment aims to measure specific knowledge structures in students. To model data arising from such assessments, cognitive diagnostic models with discrete latent variables have gained popularity in educational and…

Methodology · Statistics 2023-08-25 Seunghyun Lee , Yuqi Gu

Structural equation modeling (SEM) is a prevalent approach for studying constructs.Traditionally, these constructs are modeled as reflectively measured latent variables - common factors that account for the variance-covariance structure of…

Methodology · Statistics 2026-04-02 Tamara Schamberger , Florian Schuberth , Jörg Henseler , Yves Rosseel

Discovering the complete set of causal relations among a group of variables is a challenging unsupervised learning problem. Often, this challenge is compounded by the fact that there are latent or hidden confounders. When only observational…

Machine Learning · Computer Science 2021-01-19 Anqi Liu , Hao Liu , Tongxin Li , Saeed Karimi-Bidhendi , Yisong Yue , Anima Anandkumar

We study the identification and estimation of structural parameters in dynamic panel data logit models where decisions are forward-looking and the joint distribution of unobserved heterogeneity and observable state variables is…

Econometrics · Economics 2018-05-11 Victor Aguirregabiria , Jiaying Gu , Yao Luo

Biological systems commonly exhibit complex spatiotemporal patterns whose underlying generative mechanisms pose a significant analytical challenge. Traditional approaches to spatiodynamic inference rely on dimensionality reduction through…

Quantitative Methods · Quantitative Biology 2025-08-01 Jun Won Park , Kangyu Zhao , Sanket Rane

In this study, we present our methodology for two tasks: the Emotional Mimicry Intensity (EMI) Estimation Challenge and the Behavioural Ambivalence/Hesitancy (BAH) Recognition Challenge, both conducted as part of the 8th Workshop and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Tobias Hallmen , Robin-Nico Kampa , Fabian Deuser , Norbert Oswald , Elisabeth André

Multi-modal large language models (MLLMs), such as GPT-4o, excel at integrating text and visual data but face systematic challenges when interpreting ambiguous or incomplete visual stimuli. This study leverages statistical modeling to…

Machine Learning · Computer Science 2024-12-09 Ching-Yi Wang

Graph-structured data exhibit substantial heterogeneity in where their predictive signals originate: in some domains, node-level semantics dominate, while in others, structural patterns play a central role. This structure-semantics…

Computation and Language · Computer Science 2026-04-03 Safal Thapaliya , Zehong Wang , Jiazheng Li , Ziming Li , Yanfang Ye , Chuxu Zhang

We study the problem of learning multi-index models (MIMs), where the label depends on the input $\boldsymbol{x} \in \mathbb{R}^d$ only through an unknown $\mathsf{s}$-dimensional projection $\boldsymbol{W}_*^\mathsf{T} \boldsymbol{x} \in…

Statistics Theory · Mathematics 2026-02-11 Hugo Latourelle-Vigeant , Theodor Misiakiewicz

This paper proposes a novel latent semantic learning method for extracting high-level features (i.e. latent semantics) from a large vocabulary of abundant mid-level features (i.e. visual keywords) with structured sparse representation,…

Multimedia · Computer Science 2015-03-19 Zhiwu Lu , Yuxin Peng

A graphical model is a statistical model that is associated to a graph whose nodes correspond to variables of interest. The edges of the graph reflect allowed conditional dependencies among the variables. Graphical models admit…

Methodology · Statistics 2016-06-09 Mathias Drton , Marloes H. Maathuis

State-space models (SSM) are central to describe time-varying complex systems in countless signal processing applications such as remote sensing, networks, biomedicine, and finance to name a few. Inference and prediction in SSMs are…

Computation · Statistics 2022-10-26 Víctor Elvira , Émilie Chouzenoux

Personality traits are latent variables, and as such, are impossible to measure without the use of an assessment. Responses on the assessments can be influenced by both transient (state-related) error and measurement error, obscuring the…

Applications · Statistics 2017-06-02 Amy E. Nussbaum , Cornelis J. Potgieter , Michael Chmielewski

Empirical research in many social disciplines involves constructs that are not directly observable, such as behaviors. To model them, constructs must be operationalized using their relations with indicators. Structural equation modeling…

Methodology · Statistics 2025-07-30 Jonas Bauer , Axel Mayer , Christiane Fuchs , Tamara Schamberger