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We consider chemical reaction networks taken with mass action kinetics. The steady states of such a system are solutions to a system of polynomial equations. Even for small systems the task of finding the solutions is daunting. We develop…

Dynamical Systems · Mathematics 2011-09-08 Elisenda Feliu , Carsten Wiuf

Learning by interaction is the key to skill acquisition for most living organisms, which is formally called Reinforcement Learning (RL). RL is efficient in finding optimal policies for endowing complex systems with sophisticated behavior.…

Robotics · Computer Science 2025-11-21 Karim Farid , Nourhan Sakr

We study skew-orthogonal polynomials with respect to the weight function $\exp[-2V(x)]$, with $V(x)=\sum_{K=1}^{2d}(u_{K}/{K})x^{K}$, $u_{2d} > 0$, $d > 0$. A finite subsequence of such skew-orthogonal polynomials arising in the study of…

Mathematical Physics · Physics 2015-06-26 Saugata Ghosh

We prove that if a given reaction network $\mathcal{N}$ has a weakly reversible deficiency zero realization for all choice of rate constants, then there exists a $\textit{unique}$ weakly reversible deficiency zero network $\mathcal{N}'$…

Molecular Networks · Quantitative Biology 2025-02-26 Neal Buxton , Gheorghe Craciun , Abhishek Deshpande , Casian Pantea

We study $2$-neighbor one-dimensional cellular automata with a large number $n$ of states and randomly selected rules. We focus on the rules with weakly robust periodic solutions (WRPS). WRPS are global configurations that exhibit spatial…

Probability · Mathematics 2020-09-04 Janko Gravner , Xiaochen Liu

It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' on a wide class of biologically relevant,…

Probability · Mathematics 2014-01-20 David F. Anderson , German Enciso , Matthew Johnston

We investigate the existence of weak solutions to a multi-component system, consisting of compressible chemically reacting components, coupled with the compressible Stokes equation for the velocity. Specifically, we consider the case of…

Analysis of PDEs · Mathematics 2025-08-26 Piotr B. Mucha , Sarka Necasova , Maja Szlenk

Differential equations are a ubiquitous tool to study dynamics, ranging from physical systems to complex systems, where a large number of agents interact through a graph with non-trivial topological features. Data-driven approximations of…

Statistical Mechanics · Physics 2024-04-26 Vaiva Vasiliauskaite , Nino Antulov-Fantulin

We prove a maximal-type large deviation principle for dynamical systems with arbitrarily slow polynomial mixing rates. Also several applications, particularly to billiard systems, are presented.

Dynamical Systems · Mathematics 2022-08-09 Leonid A. Bunimovich , Yaofeng Su

We study families of polynomial dynamical systems inspired by biochemical reaction networks. We focus on complex balanced mass-action systems, which have also been called toric. They are known or conjectured to enjoy very strong dynamical…

Algebraic Geometry · Mathematics 2022-02-02 Laura Brustenga i Moncusí , Gheorghe Craciun , Miruna-Stefana Sorea

Discrete dynamics arise naturally in systems with broken temporal translation symmetry and are typically described by first-order recurrence relations representing classical or quantum Markov chains. When memory effects induced by hidden…

Statistical Mechanics · Physics 2025-10-31 Hugues Meyer , Kay Brandner

In this work we characterize a full Kostant-Toda system in terms of a family of matrix polynomials orthogonal with respect to a complex matrix measure. In order to study the solution of this dynamical system we give explicit expressions for…

Classical Analysis and ODEs · Mathematics 2013-05-14 Amílcar Branquinho , Ana Foulquié Moreno , Ana Mendes

System identification of complex and nonlinear systems is a central problem for model predictive control and model-based reinforcement learning. Despite their complexity, such systems can often be approximated well by a set of linear…

Machine Learning · Statistics 2019-05-30 Philip Becker-Ehmck , Jan Peters , Patrick van der Smagt

In this paper, we study extinction in dynamical systems generated by reaction networks. We introduce two notions: weak extinction and strong extinction, and relate them to the structure of the underlying network through Lyapunov functions…

Dynamical Systems · Mathematics 2026-01-14 Pranav Agarwal , Gheorghe Craciun , Abhishek Deshpande , Jiaxin Jin

We propose a new family of regression models for analyzing categorical responses, called multinomial link models. It consists of four classes, namely, mixed-link models that generalize existing multinomial logistic models and their…

Methodology · Statistics 2025-07-10 Tianmeng Wang , Liping Tong , Jie Yang

Mathematical models of the real world are simplified representations of complex systems. A caveat to using mathematical models is that predicted causal effects and conditional independences may not be robust under model extensions, limiting…

Methodology · Statistics 2022-08-30 Tineke Blom , Joris M. Mooij

Dynamical systems arising from chemical reaction networks with mass action kinetics are the subject of chemical reaction network theory (CRNT). In particular, this theory provides statements about uniqueness, existence, and stability of…

Dynamical Systems · Mathematics 2014-06-26 Stefan Müller , Georg Regensburger

This paper introduces algorithms for problems where a decision maker has to control a system composed of several components and has access to only partial information on the state of each component. Such problems are difficult because of…

Optimization and Control · Mathematics 2020-12-25 Victor Cohen , Axel Parmentier

In the first part of this paper, we propose new optimization-based methods for the computation of preferred (dense, sparse, reversible, detailed and complex balanced) linearly conjugate reaction network structures with mass action dynamics.…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

We investigate the possibility that for any given reaction rate vector $k$ associated with a network $G$, there exists another network $G'$ with a corresponding reaction rate vector that reproduces the mass-action dynamics generated by…

Dynamical Systems · Mathematics 2024-09-10 Samay Kothari , Jiaxin Jin , Abhishek Deshpande