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The first step in any genome assembly algorithm entails the conversion from the domain of strings and overlaps to the language of graphs and paths, typically using one of the two conventional methods: de Bruijn graphs or overlap graphs.…

Genomics · Quantitative Biology 2026-04-27 Anton Bankevich

Self-assembly is a process which is ubiquitous in natural, especially biological systems. It occurs when groups of relatively simple components spontaneously combine to form more complex structures. While such systems have inspired a large…

Computational Geometry · Computer Science 2018-07-19 Jerome Durand-Lose , Jacob Hendricks , Matthew J. Patitz , Ian Perkins , Michael Sharp

Finding structural similarities in graph data, like social networks, is a far-ranging task in data mining and knowledge discovery. A (conceptually) simple reduction would be to compute the automorphism group of a graph. However, this…

Social and Information Networks · Computer Science 2020-02-28 Stephan Doerfel , Tom Hanika , Gerd Stumme

The conception of multi-alphabetical genetics is represented. Matrix forms of the representation of the multi-level system of molecular-genetic alphabets have revealed algebraic properties of this system. These properties are connected with…

Other Quantitative Biology · Quantitative Biology 2013-01-18 Sergey V. Petoukhov

We propose a novel graph clustering method guided by additional information on the underlying structure of the clusters (or communities). The problem is formulated as the matching of a graph to a template with smaller dimension, hence…

Machine Learning · Statistics 2021-07-06 Mateus Riva , Florian Yger , Pietro Gori , Roberto M. Cesar , Isabelle Bloch

In this paper, we study the combinatorics of a subcomplex of the Bloch-Kriz cycle complex [4] used to construct the category of mixed Tate motives. The algebraic cycles we consider properly contain the subalgebra of cycles that correspond…

Algebraic Geometry · Mathematics 2018-03-16 Susama Agarwala , Owen Patashnick

Neural networks that compute over graph structures are a natural fit for problems in a variety of domains, including natural language (parse trees) and cheminformatics (molecular graphs). However, since the computation graph has a different…

Neural and Evolutionary Computing · Computer Science 2017-02-23 Moshe Looks , Marcello Herreshoff , DeLesley Hutchins , Peter Norvig

DNA sequencing is the process of determining the exact order of the nucleotide bases of an individual's genome in order to catalogue sequence variation and understand its biological implications. Whole-genome sequencing techniques produce…

Data Structures and Algorithms · Computer Science 2015-09-18 Ljiljana Brankovic , Costas S. Iliopoulos , Ritu Kundu , Manal Mohamed , Solon P. Pissis , Fatima Vayani

Complex networks have become powerful mechanisms for studying a variety of realworld systems. Consequently, many human-designed network models are proposed that reproduce nontrivial properties of complex networks, such as long-tail degree…

Social and Information Networks · Computer Science 2018-10-05 Niousha Attar , Sadegh Aliakbary

Circulant graphs are a widely studied family of graphs whose members possess varying amounts of symmetry. Although considerable progress has been made in finding the automorphism groups of circulant graphs under certain restrictions, a…

Combinatorics · Mathematics 2026-05-15 Sally Cockburn , Ryhory Hatavets , Will Swartz

We are concerned with split graphs and pseudo-split graphs whose complements are isomorphic to themselves. These special subclasses of self-complementary graphs are actually the core of self-complementary graphs. Indeed, we show that all…

Combinatorics · Mathematics 2023-12-19 Yixin Cao , Haowei Chen , Shenghua Wang

Graph Neural Networks (GNNs) have received increasing attention in many fields. However, due to the lack of prior graphs, their use for semantic labeling has been limited. Here, we propose a novel architecture called the Self-Constructing…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Qinghui Liu , Michael Kampffmeyer , Robert Jenssen , Arnt-Børre Salberg

Real networks exhibit nontrivial topological features such as heavy-tailed degree distribution, high clustering, and small-worldness. Researchers have developed several generative models for synthesizing artificial networks that are…

Social and Information Networks · Computer Science 2014-02-04 Sadegh Motallebi , Sadegh Aliakbary , Jafar Habibi

This paper focuses on representation learning for dynamic graphs with temporal interactions. A fundamental issue is that both the graph structure and the nodes own their own dynamics, and their blending induces intractable complexity in the…

Machine Learning · Computer Science 2025-10-02 Tiexin Qin , Benjamin Walker , Terry Lyons , Hong Yan , Haoliang Li

In this paper, we introduce tiled graphs as models of learning and maturing processes. We show how tiled graphs can combine graphs of learning spaces or antimatroids (partial hypercubes) and maturity models (total orders) to yield models of…

Discrete Mathematics · Computer Science 2024-03-05 Špela Kajzer , Alexander Dobler , Janja Jerebic , Martin Nöllenburg , Joachim Orthaber , Drago Bokal

A graph G is well-covered if all its maximal independent sets are of the same cardinality. Assume that a weight function w is defined on its vertices. Then G is w-well-covered if all maximal independent sets are of the same weight. For…

Discrete Mathematics · Computer Science 2016-11-22 Vadim E. Levit , David Tankus

Genome assembly asks to reconstruct an unknown string from many shorter substrings of it. Even though it is one of the key problems in Bioinformatics, it is generally lacking major theoretical advances. Its hardness stems both from…

Discrete Mathematics · Computer Science 2020-11-10 Massimo Cairo , Romeo Rizzi , Alexandru I. Tomescu , Elia C. Zirondelli

Graph data, with its structurally variable nature, represents complex real-world phenomena like chemical compounds, protein structures, and social networks. Traditional Graph Neural Networks (GNNs) primarily utilize the message-passing…

Machine Learning · Computer Science 2025-02-05 Jianming Huang , Hiroyuki Kasai

We consider the self-assembly of composite structures from a group of nanocomponents, each consisting of particles within an $N$-atom system. Self-assembly pathways and rates for nanocomposites are derived via a multiscale analysis of the…

Biological Physics · Physics 2014-01-06 Stephen Pankavich , Peter Ortoleva

The combinatorics of RNA plays a central role in biology. Mathematical biologists have several commonly-used models for RNA: words in a fixed alphabet (representing the primary sequence of nucleotides) and plane trees (representing the…

Combinatorics · Mathematics 2017-06-23 Frances Black , Elizabeth Drellich , Julianna Tymoczko