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Related papers: SurvivalGAN: Generating Time-to-Event Data for Sur…

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Synthetically generated data can improve privacy, fairness, and data accessibility; however, it can be challenging in specialized scenarios such as survival analysis. One key challenge in this setting is censoring, i.e., the timing of an…

Machine Learning · Statistics 2025-08-07 Mohd Ashhad , Ricardo Henao

Survival analysis is a cornerstone of clinical research by modeling time-to-event outcomes such as metastasis, disease relapse, or patient death. Unlike standard tabular data, survival data often come with incomplete event information due…

Machine Learning · Computer Science 2026-02-06 Marie Brockschmidt , Maresa Schröder , Stefan Feuerriegel

One of the limiting factors in training data-driven, rare-event prediction algorithms is the scarcity of the events of interest resulting in an extreme imbalance in the data. There have been many methods introduced in the literature for…

Machine Learning · Computer Science 2021-05-18 Yang Chen , Dustin J. Kempton , Azim Ahmadzadeh , Rafal A. Angryk

Clinical trials face mounting challenges: fragmented patient populations, slow enrollment, and unsustainable costs, particularly for late phase trials in oncology and rare diseases. While external control arms built from real-world data…

Machine Learning · Computer Science 2025-11-21 Perrine Chassat , Van Tuan Nguyen , Lucas Ducrot , Emilie Lanoy , Agathe Guilloux

The generation of high-quality synthetic data presents significant challenges in machine learning research, particularly regarding statistical fidelity and uncertainty quantification. Existing generative models produce compelling synthetic…

Machine Learning · Computer Science 2025-05-13 Rahul Vishwakarma , Shrey Dharmendra Modi , Vishwanath Seshagiri

Accurately predicting the time of occurrence of an event of interest is a critical problem in longitudinal data analysis. One of the main challenges in this context is the presence of instances whose event outcomes become unobservable after…

Machine Learning · Computer Science 2017-12-26 Ping Wang , Yan Li , Chandan K. Reddy

Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges…

Crash data is often greatly imbalanced, with the majority of crashes being non-fatal crashes, and only a small number being fatal crashes due to their rarity. Such data imbalance issue poses a challenge for crash severity modeling since it…

Machine Learning · Computer Science 2024-04-04 Junlan Chen , Ziyuan Pu , Nan Zheng , Xiao Wen , Hongliang Ding , Xiucheng Guo

The widespread adoption of wearable sensors has the potential to provide massive and heterogeneous time series data, driving the use of Artificial Intelligence in human sensing applications. However, data collection remains limited due to…

Machine Learning · Computer Science 2025-12-04 Flavio Di Martino , Franca Delmastro

Survival analysis is a valuable tool for estimating the time until specific events, such as death or cancer recurrence, based on baseline observations. This is particularly useful in healthcare to prognostically predict clinically important…

Machine Learning · Computer Science 2024-01-11 Ahmed H. Shahin , An Zhao , Alexander C. Whitehead , Daniel C. Alexander , Joseph Jacob , David Barber

High-quality synthetic data can support the development of effective predictive models for biomedical tasks, especially in rare diseases or when subject to compelling privacy constraints. These limitations, for instance, negatively impact…

Machine Learning · Computer Science 2023-01-24 Lorenzo Simone , Davide Bacciu

Synthetic tabular data generation has gained significant attention for its potential in data augmentation and privacy-preserving data sharing. While recent methods like diffusion and auto-regressive models (i.e., transformer) have advanced…

Machine Learning · Computer Science 2025-12-15 Jiayu Li , Zilong Zhao , Kevin Yee , Uzair Javaid , Biplab Sikdar

Applications of machine learning in healthcare often require working with time-to-event prediction tasks including prognostication of an adverse event, re-hospitalization or death. Such outcomes are typically subject to censoring due to…

Machine Learning · Computer Science 2022-08-04 Chirag Nagpal , Willa Potosnak , Artur Dubrawski

Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic…

Survival analysis is a fundamental tool for modeling time-to-event data in healthcare, engineering, and finance, where censored observations pose significant challenges. While traditional methods like the Beran estimator offer nonparametric…

Machine Learning · Computer Science 2025-06-13 Andrei V. Konstantinov , Vlada A. Efremenko , Lev V. Utkin

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…

Machine Learning · Statistics 2024-10-23 Julie Alberge , Vincent Maladière , Olivier Grisel , Judith Abécassis , Gaël Varoquaux

The modeling of time-to-event data, also known as survival analysis, requires specialized methods that can deal with censoring and truncation, time-varying features and effects, and that extend to settings with multiple competing events.…

Machine Learning · Statistics 2021-04-20 Andreas Bender , David Rügamer , Fabian Scheipl , Bernd Bischl

Synthetic data generation has emerged as a promising approach to address the challenges of using sensitive financial data in machine learning applications. By leveraging generative models, such as Generative Adversarial Networks (GANs) and…

Machine Learning · Computer Science 2025-10-31 James Meldrum , Basem Suleiman , Fethi Rabhi , Muhammad Johan Alibasa

While data sharing is crucial for knowledge development, privacy concerns and strict regulation (e.g., European General Data Protection Regulation (GDPR)) unfortunately limit its full effectiveness. Synthetic tabular data emerges as an…

Machine Learning · Computer Science 2021-06-02 Zilong Zhao , Aditya Kunar , Hiek Van der Scheer , Robert Birke , Lydia Y. Chen

Modeling lies at the core of both the financial and the insurance industry for a wide variety of tasks. The rise and development of machine learning and deep learning models have created many opportunities to improve our modeling toolbox.…

Machine Learning · Computer Science 2023-01-04 Yves-Cédric Bauwelinckx , Jan Dhaene , Tim Verdonck , Milan van den Heuvel
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