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This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson's disease progression prediction. It proposes a unified prediction framework that integrates structural…

Machine Learning · Computer Science 2025-08-22 Jiacheng Hu , Bo Zhang , Ting Xu , Haifeng Yang , Min Gao

Clustering high-dimensional spatiotemporal data using an unsupervised approach is a challenging problem for many data-driven applications. Existing state-of-the-art methods for unsupervised clustering use different similarity and distance…

Machine Learning · Computer Science 2023-09-15 Omar Faruque , Francis Ndikum Nji , Mostafa Cham , Rohan Mandar Salvi , Xue Zheng , Jianwu Wang

With the increasing prevalence of scalable file systems in the context of High Performance Computing (HPC), the importance of accurate anomaly detection on runtime logs is increasing. But as it currently stands, many state-of-the-art…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-20 Chris Egersdoerfer , Dong Dai , Di Zhang

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

Machine Learning · Computer Science 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

This paper reports on ongoing research investigating more expressive approaches to spatial-temporal trajectory clustering. Spatial-temporal data is increasingly becoming universal as a result of widespread use of GPS and mobile devices,…

Databases · Computer Science 2017-12-12 Ivens Portugal , Paulo Alencar , Donald Cowan

The lack of large labeled medical imaging datasets, along with significant inter-individual variability compared to clinically established disease classes, poses significant challenges in exploiting medical imaging information in a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Matteo Ferrante , Tommaso Boccato , Simeon Spasov , Andrea Duggento , Nicola Toschi

We propose an extension of a standard stochastic individual-based model in population dynamics which broadens the range of biological applications. Our primary motivation is modelling of immunotherapy of malignant tumours. In this context…

Populations and Evolution · Quantitative Biology 2016-04-18 Martina Baar , Loren Coquille , Hannah Mayer , Michael Hölzel , Meri Rogava , Thomas Tüting , Anton Bovier

Computer vision-based methods have valuable use cases in precision medicine, and recognizing facial phenotypes of genetic disorders is one of them. Many genetic disorders are known to affect faces' visual appearance and geometry. Automated…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Ömer Sümer , Fabio Hellmann , Alexander Hustinx , Tzung-Chien Hsieh , Elisabeth André , Peter Krawitz

Cancer has become one of the most widespread diseases in the world. Specifically, breast cancer is diagnosed more often than any other type of cancer. However, breast cancer patients and their individual tumors are often unique. Identifying…

Quantitative Methods · Quantitative Biology 2016-12-06 Chenzhe Qian

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

We address the problem of cluster identity estimation in a personalized federated learning (PFL) setting in which users aim to learn different personal models. The backbone of effective learning in such a setting is to cluster users into…

Machine Learning · Computer Science 2025-03-26 Abdulmoneam Ali , Ahmed Arafa

Temporal Heterogeneous Networks play a crucial role in capturing the dynamics and heterogeneity inherent in various real-world complex systems, rendering them a noteworthy research avenue for link prediction. However, existing methods fail…

Social and Information Networks · Computer Science 2025-12-12 Yu Tai , Xinglong Wu , Hongwei Yang , Hui He , Duanjing Chen , Yuanming Shao , Weizhe Zhang

Medical time series has been playing a vital role in real-world healthcare systems as valuable information in monitoring health conditions of patients. Accurate classification for medical time series, e.g., Electrocardiography (ECG)…

Machine Learning · Computer Science 2025-02-10 Wei Fan , Jingru Fei , Dingyu Guo , Kun Yi , Xiaozhuang Song , Haolong Xiang , Hangting Ye , Min Li

Deploying models on target domain data subject to distribution shift requires adaptation. Test-time training (TTT) emerges as a solution to this adaptation under a realistic scenario where access to full source domain data is not available…

Computer Vision and Pattern Recognition · Computer Science 2022-10-17 Yongyi Su , Xun Xu , Kui Jia

The progression of chronic diseases often follows highly variable trajectories, and the underlying factors remain poorly understood. Standard mixed-effects models typically represent inter-patient differences as random deviations around a…

Time-series anomaly detection is a popular topic in both academia and industrial fields. Many companies need to monitor thousands of temporal signals for their applications and services and require instant feedback and alerts for potential…

Machine Learning · Computer Science 2020-09-10 Yuanxiang Ying , Juanyong Duan , Chunlei Wang , Yujing Wang , Congrui Huang , Bixiong Xu

Learning representation from unlabeled time series data is a challenging problem. Most existing self-supervised and unsupervised approaches in the time-series domain do not capture low and high-frequency features at the same time. Further,…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Vandan Gorade , Azad Singh , Deepak Mishra

We propose a node clustering method for time-varying graphs based on the assumption that the cluster labels are changed smoothly over time. Clustering is one of the fundamental tasks in many science and engineering fields including signal…

Machine Learning · Computer Science 2023-05-12 Katsuki Fukumoto , Koki Yamada , Yuichi Tanaka , Hoi-To Wai

Phenotypic characterization is essential for understanding heterogeneity in chronic diseases and for guiding personalized interventions. Long COVID, a complex and persistent condition, yet its clinical subphenotypes remain poorly…

Machine Learning · Computer Science 2026-03-20 Jing Wang , Jie Shen , Amar Sra , Qiaomin Xie , Jeremy C Weiss

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing…

Biological Physics · Physics 2015-05-14 Cesar A. Hidalgo , Nicholas Blumm , Albert-Laszlo Barabasi , Nicholas Christakis