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Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

Medical Physics · Physics 2020-06-17 Changhee Lee , Mihaela van der Schaar

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

Machine Learning · Computer Science 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

Traumatic Brain Injury (TBI) presents a broad spectrum of clinical presentations and outcomes due to its inherent heterogeneity, leading to diverse recovery trajectories and varied therapeutic responses. While many studies have delved into…

Machine Learning · Computer Science 2024-08-22 Hamid Ghaderi , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

Unsupervised learning is often used to uncover clusters in data. However, different kinds of noise may impede the discovery of useful patterns from real-world time-series data. In this work, we focus on mitigating the interference of…

Machine Learning · Statistics 2021-12-07 Irene Y. Chen , Rahul G. Krishnan , David Sontag

Clinical time series data are critical for patient monitoring and predictive modeling. These time series are typically multivariate and often comprise hundreds of heterogeneous features from different data sources. The grouping of features…

Machine Learning · Computer Science 2025-11-12 Fedor Sergeev , Manuel Burger , Polina Leshetkina , Vincent Fortuin , Gunnar Rätsch , Rita Kuznetsova

Models have been proposed to extract temporal patterns from longitudinal electronic health records (EHR) for clinical predictive models. However, the common relations among patients (e.g., receiving the same medical treatments) were rarely…

Applications · Statistics 2019-09-27 Yue Wang , Tong Wu , Yunlong Wang , Gao Wang

Learning decent representations from unlabeled time-series data with temporal dynamics is a very challenging task. In this paper, we propose an unsupervised Time-Series representation learning framework via Temporal and Contextual…

Machine Learning · Computer Science 2021-06-29 Emadeldeen Eldele , Mohamed Ragab , Zhenghua Chen , Min Wu , Chee Keong Kwoh , Xiaoli Li , Cuntai Guan

Time series data, defined by equally spaced points over time, is essential in fields like medicine, telecommunications, and energy. Analyzing it involves tasks such as classification, clustering, prototyping, and regression. Classification…

Machine Learning · Computer Science 2025-02-27 Ali Ismail-Fawaz

Self-supervised learning approaches provide a promising direction for clustering multivariate time-series data. However, real-world time-series data often include missing values, and the existing approaches require imputing missing values…

Machine Learning · Computer Science 2023-05-30 Hamid Ghaderi , Brandon Foreman , Amin Nayebi , Sindhu Tipirneni , Chandan K. Reddy , Vignesh Subbian

Tensor decomposition has recently been gaining attention in the machine learning community for the analysis of individual traces, such as Electronic Health Records (EHR). However, this task becomes significantly more difficult when the data…

Machine Learning · Computer Science 2024-05-03 Hana Sebia , Thomas Guyet , Etienne Audureau

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

Understanding and distinguishing temporal patterns in time series data is essential for scientific discovery and decision-making. For example, in biomedical research, uncovering meaningful patterns in physiological signals can improve…

Machine Learning · Computer Science 2025-12-16 Yu-Chia Huang , Juntong Chen , Dongyu Liu , Kwan-Liu Ma

Cancer subtyping plays a crucial role in informing prognosis and guiding personalized treatment strategies. However, conventional subtyping approaches often rely on static, biopsy-derived scores that hardly capture the biological…

Methodology · Statistics 2026-03-12 Lara Cavinato , Marco Rocchi , Luca Viganò , Francesca Ieva

The last decades have not only been characterized by an explosive growth of data, but also an increasing appreciation of data as a valuable resource. Their value comes with the ability to extract meaningful patterns that are of economic,…

Machine Learning · Statistics 2020-02-27 Jonas I. Liechti , Sebastian Bonhoeffer

Patient stratification identifying clinically meaningful subgroups is essential for advancing personalized medicine through improved diagnostics and treatment strategies. Electronic health records (EHRs), particularly those from intensive…

Machine Learning · Computer Science 2025-06-09 Dimitrios Proios , Alban Bornet , Anthony Yazdani , Jose F Rodrigues , Douglas Teodoro

Traditional machine learning methods face two main challenges in dealing with healthcare predictive analytics tasks. First, the high-dimensional nature of healthcare data needs labor-intensive and time-consuming processes to select an…

Machine Learning · Computer Science 2022-09-16 Mohammad Amin Morid , Olivia R. Liu Sheng , Joseph Dunbar

Identifying a patient's key problems over time is a common task for providers at the point care, yet a complex and time-consuming activity given current electric health records. To enable a problem-oriented summarizer to identify a…

Applications · Statistics 2020-03-26 Gal Levy-Fix , Jason Zucker , Konstantin Stojanovic , Noémie Elhadad

Time series shapelets are discriminative subsequences that have been recently found effective for time series clustering (TSC). The shapelets are convenient for interpreting the clusters. Thus, the main challenge for TSC is to discover…

Machine Learning · Computer Science 2022-08-19 Guozhong Li , Byron Choi , Jianliang Xu , Sourav S Bhowmick , Daphne Ngar-yin Mah , Grace Lai-Hung Wong

Time-series classification is an important problem for the data mining community due to the wide range of application domains involving time-series data. A recent paradigm, called shapelets, represents patterns that are highly predictive…

Machine Learning · Computer Science 2015-03-12 Josif Grabocka , Martin Wistuba , Lars Schmidt-Thieme

Unsupervised clustering of temporal data is both challenging and crucial in machine learning. In this paper, we show that neither traditional clustering methods, time series specific or even deep learning-based alternatives generalise well…

Machine Learning · Computer Science 2020-10-13 Nuno Mota Goncalves , Ioana Giurgiu , Anika Schumann
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