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The nature of neural codes is central to neuroscience. Do neurons encode information through relatively slow changes in the emission rates of individual spikes (rate code), or by the precise timing of every spike (temporal codes)? Here we…

Quantitative Methods · Quantitative Biology 2018-03-08 Agnieszka Pregowska , Ehud Kaplan , Janusz Szczepanski

Immune events such as infection, vaccination, and a combination of the two result in distinct time-dependent antibody responses in affected individuals. These responses and event prevalences combine non-trivially to govern antibody levels…

Populations and Evolution · Quantitative Biology 2024-04-16 Prajakta Bedekar , Rayanne A. Luke , Anthony J. Kearsley

We propose an information criterion for determining an unknown number of periodic components in functional time series. Identifying the number of frequencies in large-scale time series has been a central focus. To achieve this goal, we…

Methodology · Statistics 2026-03-24 Rinka Sagawa , Yan Liu , Valentin Patilea

This article introduces the physics of information in the context of molecular biology and genomics. Entropy and information, the two central concepts of Shannon's theory of information and communication, are often confused with each other…

Biomolecules · Quantitative Biology 2007-05-23 Christoph Adami

Researchers in explainable artificial intelligence have developed numerous methods for helping users understand the predictions of complex supervised learning models. By contrast, explaining the $\textit{uncertainty}$ of model outputs has…

Machine Learning · Statistics 2023-11-01 David S. Watson , Joshua O'Hara , Niek Tax , Richard Mudd , Ido Guy

The paper introduces a novel topological method for prediction and modeling for a nonlinear time--series that exhibit recurring patterns. According to the model, global manifold of the reconstructed state--space can be approximated by a few…

Chaotic Dynamics · Physics 2017-11-21 Sajini Anand P S , Prabhakar G Vaidya

Information diagram and the I-measure are useful mnemonics where random variables are treated as sets, and entropy and mutual information are treated as a signed measure. Although the I-measure has been successful in machine proofs of…

Information Theory · Computer Science 2023-07-17 Cheuk Ting Li

During a spontaneous change, a macroscopic physical system will evolve towards a macro-state with more realizations. This observation is at the basis of the Statistical Mechanical version of the Second Law of Thermodynamics, and it provides…

Statistical Mechanics · Physics 2020-04-22 Mengjie Zu , Arunkumar Bupathy , Daan Frenkel , Srikanth Sastry

We show that supervised neural information retrieval (IR) models are prone to learning sparse attention patterns over passage tokens, which can result in key phrases including named entities receiving low attention weights, eventually…

Computation and Language · Computer Science 2022-04-26 Revanth Gangi Reddy , Md Arafat Sultan , Martin Franz , Avirup Sil , Heng Ji

There is a lack of methodological results for continuous time change detection due to the challenges of noninformative prior specification and efficient posterior inference in this setting. Most methodologies to date assume data are…

Methodology · Statistics 2025-04-28 Dan Cunha , Mark Friedl , Luis Carvalho

Irregularly sampled time series are increasingly prevalent, particularly in medical domains. While various specialized methods have been developed to handle these irregularities, effectively modeling their complex dynamics and pronounced…

Machine Learning · Computer Science 2023-11-01 Zekun Li , Shiyang Li , Xifeng Yan

We consider the problem of learning a policy for a Markov decision process consistent with data captured on the state-actions pairs followed by the policy. We assume that the policy belongs to a class of parameterized policies which are…

Optimization and Control · Mathematics 2017-01-24 Manjesh K. Hanawal , Hao Liu , Henghui Zhu , Ioannis Ch. Paschalidis

In this paper, we introduce a new adaptive data analysis method to study trend and instantaneous frequency of nonlinear and non-stationary data. This method is inspired by the Empirical Mode Decomposition method (EMD) and the recently…

Numerical Analysis · Mathematics 2012-02-28 Thomas Y. hou , Zuoqiang Shi

The paper studies information-theoretic opacity, an information-flow privacy property, in a setting involving two agents: A planning agent who controls a stochastic system and an observer who partially observes the system states. The goal…

Systems and Control · Electrical Eng. & Systems 2024-11-20 Chongyang Shi , Yuheng Bu , Jie Fu

Spiking activity from populations of neurons display causal interactions and memory effects. Therefore, they are expected to show some degree of irreversibility in time. Motivated by the spike train statistics, in this paper we build a…

Biological Physics · Physics 2015-12-07 Rodrigo Cofre , Cesar Maldonado

We investigate the memory properties of discrete sequences built upon a finite number of states. We find that the block entropy can reliably determine the memory for systems modeled as Markov chains of arbitrary finite order. Further, we…

Statistical Mechanics · Physics 2022-11-21 Juan De Gregorio , David Sanchez , Raul Toral

The purpose of this study is to provide a new methodology of how one can consistently estimate a change-point in time series data. In contrast with previous studies, the suggested methodology employs only the empirical spectral density and…

Methodology · Statistics 2016-11-22 Gyorgy H. Terdik , Stergios B. Fotopoulos , Venkata K. Jandhyala

The traditional approach to the quantitative study of segregation is to employ indices that are selected by ``desirable properties''. Here, we detail how information theory underpins entropy-based indices and demonstrate how desirable…

Physics and Society · Physics 2022-12-15 Boris Barron , Yunus A. Kinkhabwala , Chriss Hess , Matthew Hall , Itai Cohen , Tomás A. Arias

Information theory is an outstanding framework to measure uncertainty, dependence and relevance in data and systems. It has several desirable properties for real world applications: it naturally deals with multivariate data, it can handle…

Machine Learning · Statistics 2024-10-30 Valero Laparra , J. Emmanuel Johnson , Gustau Camps-Valls , Raul Santos-Rodríguez , Jesus Malo

The mutual information between stimulus and spike-train response is commonly used to monitor neural coding efficiency, but neuronal computation broadly conceived requires more refined and targeted information measures of input-output joint…

Neurons and Cognition · Quantitative Biology 2015-04-21 Sarah E. Marzen , Michael R. DeWeese , James P. Crutchfield
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