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In recent years, the denoising diffusion model has achieved remarkable success in image segmentation modeling. With its powerful nonlinear modeling capabilities and superior generalization performance, denoising diffusion models have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Weiping Ding , Sheng Geng , Haipeng Wang , Jiashuang Huang , Tianyi Zhou

Deep learning has received extensive research interest in developing new medical image processing algorithms, and deep learning based models have been remarkably successful in a variety of medical imaging tasks to support disease detection…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Xuxin Chen , Ximin Wang , Ke Zhang , Kar-Ming Fung , Theresa C. Thai , Kathleen Moore , Robert S. Mannel , Hong Liu , Bin Zheng , Yuchen Qiu

Diffusion models have emerged as a leading framework in generative modeling, poised to transform the traditionally slow and costly process of drug discovery. This review provides a systematic comparison of their application in designing two…

Machine Learning · Computer Science 2025-11-27 Yiquan Wang , Yahui Ma , Yuhan Chang , Jiayao Yan , Jialin Zhang , Minnuo Cai , Kai Wei

Machine Learning algorithms have had a profound impact on the field of computer science over the past few decades. These algorithms performance is greatly influenced by the representations that are derived from the data in the learning…

Image classification serves as the cornerstone of computer vision, traditionally achieved through discriminative models based on deep neural networks. Recent advancements have introduced classification methods derived from generative…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Chunxiao Li , Xiaoxiao Wang , Boming Miao , Chuanlong Xie , Zizhe Wang , Yao Zhu

Inverting visual representations within deep neural networks (DNNs) presents a challenging and important problem in the field of security and privacy for deep learning. The main goal is to invert the features of an unidentified target image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Sai Qian Zhang , Ziyun Li , Chuan Guo , Saeed Mahloujifar , Deeksha Dangwal , Edward Suh , Barbara De Salvo , Chiao Liu

Image restoration aims to enhance low quality images, producing high quality images that exhibit natural visual characteristics and fine semantic attributes. Recently, the diffusion model has emerged as a powerful technique for image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jiangtong Tan , Feng Zhao

We propose self-diffusion, a novel framework for solving inverse problems without relying on pretrained generative models. Traditional diffusion-based approaches require training a model on a clean dataset to learn to reverse the forward…

Machine Learning · Computer Science 2025-12-09 Guanxiong Luo , Shoujin Huang , Yanlong Yang

Low-light image enhancement (LLIE) is vital for safety-critical applications such as surveillance, autonomous navigation, and medical imaging, where visibility degradation can impair downstream task performance. Recently, diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Eashan Adhikarla , Yixin Liu , Brian D. Davison

Diffusion models have emerged as powerful generative frameworks by progressively adding noise to data through a forward process and then reversing this process to generate realistic samples. While these models have achieved strong…

Machine Learning · Computer Science 2025-03-04 Xingzhuo Guo , Yu Zhang , Baixu Chen , Haoran Xu , Jianmin Wang , Mingsheng Long

Diffusion models (DMs) have recently been introduced in image deblurring and exhibited promising performance, particularly in terms of details reconstruction. However, the diffusion model requires a large number of inference iterations to…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Zheng Chen , Yulun Zhang , Ding Liu , Bin Xia , Jinjin Gu , Linghe Kong , Xin Yuan

Diffusion-based generative models (DBGMs) perturb data to a target noise distribution and reverse this process to generate samples. The choice of noising process, or inference diffusion process, affects both likelihoods and sample quality.…

Machine Learning · Computer Science 2023-03-06 Raghav Singhal , Mark Goldstein , Rajesh Ranganath

Diffusion models have been widely used in the generative domain due to their convincing performance in modeling complex data distributions. Moreover, they have shown competitive results on discriminative tasks, such as image segmentation.…

Sound · Computer Science 2025-01-14 Hounsu Kim , Taegyun Kwon , Juhan Nam

Diffusion models are learning pattern-learning systems to model and sample from data distributions with three functional components namely the forward process, the reverse process, and the sampling process. The components of diffusion…

Machine Learning · Computer Science 2025-06-02 Ziyi Chang , George Alex Koulieris , Hyung Jin Chang , Hubert P. H. Shum

Diffusion Models (DMs) have disrupted the image Super-Resolution (SR) field and further closed the gap between image quality and human perceptual preferences. They are easy to train and can produce very high-quality samples that exceed the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Brian B. Moser , Arundhati S. Shanbhag , Federico Raue , Stanislav Frolov , Sebastian Palacio , Andreas Dengel

Generative models have recently undergone significant advancement due to the diffusion models. The success of these models can be often attributed to their use of guidance techniques, such as classifier or classifier-free guidance, which…

Computer Vision and Pattern Recognition · Computer Science 2023-01-31 Gyeongnyeon Kim , Wooseok Jang , Gyuseong Lee , Susung Hong , Junyoung Seo , Seungryong Kim

Diffusion models have achieved state-of-the-art synthesis quality on both visual and audio tasks, and recent works further adapt them to textual data by diffusing on the embedding space. In this paper, we conduct systematic studies of the…

Computation and Language · Computer Science 2024-04-23 Zhujin Gao , Junliang Guo , Xu Tan , Yongxin Zhu , Fang Zhang , Jiang Bian , Linli Xu

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

Denoising diffusion probabilistic models have recently received much research attention since they outperform alternative approaches, such as GANs, and currently provide state-of-the-art generative performance. The superior performance of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Dmitry Baranchuk , Ivan Rubachev , Andrey Voynov , Valentin Khrulkov , Artem Babenko

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso