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Robust, broadly applicable fluid-structure interaction (FSI) algorithms remain a challenge for computational mechanics. In previous work, we introduced an immersed interface method (IIM) for discrete surfaces and an extension based on an…

Computational Physics · Physics 2025-11-14 Qi Sun , Ebrahim M. Kolahdouz , Boyce E. Griffith

Diffusion MRI (dMRI) provides unique insights into fetal brain microstructure in utero. Longitudinal and cross-sectional fetal dMRI studies can reveal crucial neurodevelopmental changes but require precise spatial alignment across scans and…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Bo Li , Qi Zeng , Simon K. Warfield , Davood Karimi

Resting-state functional Magnetic Resonance Imaging (fMRI) is a powerful imaging technique for studying functional development of the brain in utero. However, unpredictable and excessive movement of fetuses has limited clinical application…

Diffusion-weighted magnetic resonance imaging (dMRI) is the only non-invasive tool for studying white matter tracts and structural connectivity of the brain. These assessments rely heavily on tractography techniques, which reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Weide Liu , Camilo Calixto , Simon K. Warfield , Davood Karimi

Prenatal maternal stress alters maternal-fetal heart rate coupling, as demonstrated by the Fetal Stress Index derived from bivariate phase-rectified signal averaging. Here, we extend this framework using information-theoretical measures to…

Quantitative Methods · Quantitative Biology 2026-01-05 Nicolas B. Garnier , Maria S. Molinet , Marta C. Antonelli , Silvia M. Lobmaier , Martin G. Frasch

We present a new approach for the mechanically consistent modelling and simulation of fluid-structure interactions with contact. The fundamental idea consists of combining a relaxed contact formulation with the modelling of seepage through…

Numerical Analysis · Mathematics 2022-03-02 Erik Burman , Miguel A. Fernández , Stefan Frei , Fannie M. Gerosa

An important ingredient of any moving-mesh method for fluid-structure interaction (FSI) problems is the mesh deformation technique (MDT) used to adapt the computational mesh in the moving fluid domain. An ideal technique is computationally…

Computational Engineering, Finance, and Science · Computer Science 2020-06-26 Alexander Shamanskiy , Bernd Simeon

In this paper we construct a novel technique for eliminating and recovering the pressure for a fluid-structure interaction model. This pressure elimination methodology is valid for general bounded Lipschitz domains. The specific…

Analysis of PDEs · Mathematics 2026-01-27 George Avalos , Yuhao Mu

SUMMARY This work aims at quantifying the effect of inherent uncertainties from cardiac output on the sensitivity of a human compliant arterial network response based on stochastic simulations of a reduced-order pulse wave propagation…

Numerical Analysis · Mathematics 2016-06-22 A Brault , L Dumas , D Lucor

Fetal heart rate variability (fHRV) is an important indicator of health and disease, yet its physiological origins, neural contributions in particular, are not well understood. We aimed to develop novel experimental and data analytical…

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Medical Physics · Physics 2019-04-17 Stefania Scarsoglio , Caterina Gallo , Andrea Saglietto , Luca Ridolfi , Matteo Anselmino

Three-field Fluid-Structure Interaction (FSI) formulations for fluid and solid are applied and compared to the standard two field-one field formulation for fluid and solid, respectively. Both formulations are applied in a non linear setting…

Numerical Analysis · Mathematics 2020-10-13 Alexis Tello , Ramon Codina

Intrapartum fetal heart rate (FHR) monitoring constitutes a reference tool in clinical practice to assess the baby health status and to detect fetal acidosis. It is usually analyzed by visual inspection grounded on FIGO criteria.…

We derive a Nitsche-based formulation for fluid-structure interaction (FSI) problems with contact. The approach is based on the work of Chouly and Hild [SIAM Journal on Numerical Analysis. 2013;51(2):1295--1307] for contact problems in…

Numerical Analysis · Mathematics 2018-08-28 Erik Burman , Miguel A. Fernández , Stefan Frei

An arteriovenous fistula, created by artificially connecting segments of a patient's vasculature, is the preferred way to gain access to the bloodstream for kidney dialysis. The increasing power and availability of supercomputing…

Medical Physics · Physics 2021-06-14 J. W. S. McCullough , P. V. Coveney

We propose a novel fluid-structure interaction (FSI) scheme using the entropic multi-relaxation time lattice Boltzmann (KBC) model for the fluid domain in combination with a nonlinear finite element solver for the structural part. We show…

Fluid Dynamics · Physics 2018-02-28 Benedikt Dorschner , Shyam S. Chikatamarla , Ilya V. Karlin

Computational Fluid Dynamics (CFD) is used to assist in designing artificial valves and planning procedures, focusing on local flow features. However, assessing the impact on overall cardiovascular function or predicting longer-term…

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

A noteworthy aspect in blood flow modeling is the definition of the mechanical interaction between the fluid flow and the biological structure that contains it, namely the vessel wall. It has been demonstrated that the addition of a viscous…

Fluid Dynamics · Physics 2022-06-14 Francesco Piccioli , Giulia Bertaglia , Alessandro Valiani , Valerio Caleffi

Brain tissue is a heterogeneous material, constituted by a soft matrix filled with cerebrospinal fluid. The interactions between, and the complexity of each of these components are responsible for the non-linear rate-dependent behaviour…

Quantitative Methods · Quantitative Biology 2021-02-23 Michele Terzano , Andrea Spagnoli , Daniele Dini , Antonio Elia Forte