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Scaling test-time compute is a promising axis for improving LLM capabilities. However, test-time compute can be scaled in a variety of ways, and effectively combining different approaches remains an active area of research. Here, we explore…

Machine Learning · Computer Science 2025-02-04 Ryan Ehrlich , Bradley Brown , Jordan Juravsky , Ronald Clark , Christopher Ré , Azalia Mirhoseini

Sequential importance sampling algorithms have been defined to estimate likelihoods in models of ancestral population processes. However, these algorithms are based on features of the models with constant population size, and become…

Statistics Theory · Mathematics 2016-03-24 Coralie Merle , Raphaël Leblois , François Rousset , Pierre Pudlo

In epidemiological studies of time-to-event data, a quantity of interest to the clinician and the patient is the risk of an event given a covariate profile. However, methods relying on time matching or risk-set sampling (including Cox…

Methodology · Statistics 2020-09-23 Sahir Rai Bhatnagar , Maxime Turgeon , Jesse Islam , James A. Hanley , Olli Saarela

Code often suffers from performance bugs. These bugs necessitate the research and practice of code optimization. Traditional rule-based methods rely on manually designing and maintaining rules for specific performance bugs (e.g., redundant…

Software Engineering · Computer Science 2025-12-30 Yue Wu , Minghao Han , Ruiyin Li , Peng Liang , Amjed Tahir , Zengyang Li , Qiong Feng , Mojtaba Shahin

We present EPITIME (EPidemic Integral models TIMe profile Explorer), a computational framework for the simulation of two classes of integral epidemic models: an age of infection model and an information dependent behavioural model. The…

Quantitative Methods · Quantitative Biology 2026-05-04 Bruno Buonomo , Eleonora Messina , Claudia Panico , Mario Pezzella , Gaetano Zanghirati

Structural equation modelling (SEM) is a multivariate statistical technique for estimating complex relationships between observed and latent variables. Although numerous SEM packages exist, each of them has limitations. Some packages are…

Applications · Statistics 2021-06-02 Meshcheryakov Georgy , Igolkina Anna

Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology. To address this…

Machine Learning · Computer Science 2025-07-11 Alba Garrido , Alejandro Almodóvar , Patricia A. Apellániz , Juan Parras , Santiago Zazo

In recent years, code security has become increasingly important, especially with the rise of interconnected technologies. Detecting vulnerabilities early in the software development process has demonstrated numerous benefits. Consequently,…

Software Engineering · Computer Science 2024-07-22 José Gonçalves , Tiago Dias , Eva Maia , Isabel Praça

Survival analysis is a classic problem in statistics with important applications in healthcare. Most machine learning models for survival analysis are black-box models, limiting their use in healthcare settings where interpretability is…

Machine Learning · Computer Science 2024-11-12 Mike Van Ness , Billy Block , Madeleine Udell

The classification problem's complexity assessment is an essential element of many topics in the supervised learning domain. It plays a significant role in meta-learning -- becoming the basis for determining meta-attributes or…

Machine Learning · Computer Science 2022-07-15 Joanna Komorniczak , Pawel Ksieniewicz

In this study, we evaluated the performance of SAIPy, an open-source Python package for deep learning-based seismic data analysis, by applying its single-station monitoring tools and extending its use to a seismic network based approach,…

The bullwhip effect remains operationally persistent despite decades of analytical research. Two computational deficiencies hinder progress: the absence of modular open-source simulation tools for multi-echelon inventory dynamics with…

Optimization and Control · Mathematics 2026-04-16 Mansur M. Arief

Accurately predicting the time of occurrence of an event of interest is a critical problem in longitudinal data analysis. One of the main challenges in this context is the presence of instances whose event outcomes become unobservable after…

Machine Learning · Computer Science 2017-12-26 Ping Wang , Yan Li , Chandan K. Reddy

EpiLearn is a Python toolkit developed for modeling, simulating, and analyzing epidemic data. Although there exist several packages that also deal with epidemic modeling, they are often restricted to mechanistic models or traditional…

Machine Learning · Computer Science 2024-09-10 Zewen Liu , Yunxiao Li , Mingyang Wei , Guancheng Wan , Max S. Y. Lau , Wei Jin

Statistical model checking avoids the exponential growth of states associated with probabilistic model checking by estimating properties from multiple executions of a system and by giving results within confidence bounds. Rare properties…

Performance · Computer Science 2012-01-26 Cyrille Jégourel , Axel Legay , Sean Sedwards

Survival analysis is a valuable tool for estimating the time until specific events, such as death or cancer recurrence, based on baseline observations. This is particularly useful in healthcare to prognostically predict clinically important…

Machine Learning · Computer Science 2024-01-11 Ahmed H. Shahin , An Zhao , Alexander C. Whitehead , Daniel C. Alexander , Joseph Jacob , David Barber

There has been increasing interest in modeling survival data using deep learning methods in medical research. In this paper, we proposed a Bayesian hierarchical deep neural networks model for modeling and prediction of survival data.…

Methodology · Statistics 2021-09-20 Dai Feng , Lili Zhao

Structural Equation Modeling (SEM) is an umbrella term that includes numerous multivariate statistical techniques that are employed throughout a plethora of research areas, ranging from social to natural sciences. Until recently, SEM…

Applications · Statistics 2021-06-10 Georgy Meshcheryakov , Anna A. Igolkina , Maria G. Samsonova

Multiplexed imaging data are revolutionizing our understanding of the composition and organization of tissues and tumors. A critical aspect of such tissue profiling is quantifying the spatial relationship relationships among cells at…

Quantitative Methods · Quantitative Biology 2024-05-06 Ajit J. Nirmal , Peter K. Sorger

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell
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