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At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

Most functional magnetic resonance imaging studies rely on estimates of hierarchically organized functional brain networks whose segregation and integration reflect the cognitive and behavioral changes in humans. However, most existing…

Neurons and Cognition · Quantitative Biology 2026-04-17 Lingbin Bian , Nizhuan Wang , Leonardo Novelli , Jonathan Keith , Adeel Razi

Brain functional connectome, the collection of interconnected neural circuits along functional networks, is one of the most cutting edge neuroimaging traits, and has a potential to play a mediating role within the effect pathway between an…

Methodology · Statistics 2022-01-28 Yize Zhao , Tianqi Chen , Jiachen Cai , Sarah Lichenstein , Marc Potenza , Sarah Yip

Integrating high-dimensional, heterogeneous data from multi-site cohort studies with complex hierarchical structures poses significant feature selection and prediction challenges. We extend the Bayesian Integrative Analysis and Prediction…

Methodology · Statistics 2025-01-30 Aidan Neher , Apostolos Stamenos , Mark Fiecas , Sandra Safo , Thierry Chekouo

Some evidence suggests that people with autism spectrum disorder exhibit patterns of brain functional dysconnectivity relative to their typically developing peers, but specific findings have yet to be replicated. To facilitate this…

Methodology · Statistics 2025-03-03 Hyoshin Kim , Sujit K. Ghosh , Emily C. Hector

This article focuses on the problem of predicting a response variable based on a network-valued predictor. Our motivation is the development of interpretable and accurate predictive models for cognitive traits and neuro-psychiatric…

Methodology · Statistics 2022-02-14 Subharup Guha , Rex Jung , David Dunson

Understanding the sequence of cognitive operations that underlie decision-making is a fundamental challenge in cognitive neuroscience. Traditional approaches often rely on group-level statistics, which obscure trial-by-trial variations in…

Neurons and Cognition · Quantitative Biology 2025-04-15 Rick den Otter , Gabriel Weindel , Sjoerd Stuit , Leendert van Maanen

Network models provide a powerful framework for analysing single-cell count data, facilitating the characterisation of cellular identities, disease mechanisms, and developmental trajectories. However, uncertainty modeling in unsupervised…

Genomics · Quantitative Biology 2026-04-27 Shanshan Ren , Thomas E. Bartlett , Lina Gerontogianni , Swati Chandna

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

Neurons and Cognition · Quantitative Biology 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

Brain responses related to working memory originate from distinct brain areas and oscillate at different frequencies. EEG signals with high temporal correlation can effectively capture these responses. Therefore, estimating the functional…

Machine Learning · Computer Science 2024-05-01 Harshini Gangapuram , Vidya Manian

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

Most humans have the good fortune to live their lives embedded in richly structured social groups. Yet, it remains unclear how humans acquire knowledge about these social structures to successfully navigate social relationships. Here we…

Neurons and Cognition · Quantitative Biology 2019-04-23 Steven H. Tompson , Ari E. Kahn , Emily B. Falk , Jean M. Vettel , Danielle S. Bassett

This paper presents a Bayesian approach to learning the connectivity structure of a group of neurons from data on configuration frequencies. A major objective of the research is to provide statistical tools for detecting changes in firing…

Machine Learning · Computer Science 2013-02-18 Kathryn Blackmond Laskey , Laura Martignon

Modern neural recording techniques allow neuroscientists to obtain spiking activity of multiple neurons from different brain regions over long time periods, which requires new statistical methods to be developed for understanding structure…

Applications · Statistics 2023-12-29 Ganchao Wei

To understand the biological characteristics of neurological disorders with functional connectivity (FC), recent studies have widely utilized deep learning-based models to identify the disease and conducted post-hoc analyses via explainable…

Machine Learning · Computer Science 2023-10-09 Eunsong Kang , Da-woon Heo , Jiwon Lee , Heung-Il Suk

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

Recurrent neural networks (RNNs) trained on compositional tasks can exhibit functional modularity, in which neurons can be clustered by activity similarity and participation in shared computational subtasks. Unlike brains, these RNNs do not…

Neurons and Cognition · Quantitative Biology 2023-10-12 Ziming Liu , Mikail Khona , Ila R. Fiete , Max Tegmark

Several approaches to cognition and intelligence research rely on statistics-based models testing, namely factor analysis. In the present work we exploit the emerging dynamical systems perspective putting the focus on the role of the…

Physics and Society · Physics 2018-03-15 Gemma Rosell-Tarragó , Emanuele Cozzo , Albert Díaz-Guilera

The study of random networks in a neuroscientific context has developed extensively over the last couple of decades. By contrast, techniques for the statistical analysis of these networks are less developed. In this paper, we focus on the…

Neurons and Cognition · Quantitative Biology 2017-07-11 Daniel Fraiman , Ricardo Fraiman