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Many cellular processes require a polarization axis which generally initially emerges as an inhomogeneous distribution of molecular markers in the cell. We present a simple analytical model of a general mechanism of cell polarization taking…

Cell Behavior · Quantitative Biology 2009-10-21 Rhoda J. Hawkins , Olivier Benichou , Matthieu Piel , Raphael Voituriez

A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…

Biological Physics · Physics 2022-02-03 H. Chelly , A. Jahangiri , M. Mireux , J. Étienne , D. K. Dysthe , C. Verdier , P. Recho

Cytoskeletal filaments transported by surface immobilized molecular motors with one end pinned to the surface have been observed to spiral in a myosin-driven actin 'gliding assay'. The radius of the spiral was shown to scale with motor…

Soft Condensed Matter · Physics 2025-08-15 Aman Soni , Shivani A. Yadav , Chaitanya A. Athale

Cellular cortex, which is a highly viscous thin cytoplasmic layer just below the cell membrane, controls the cell's mechanical properties, which can be characterized by a hydrodynamic length scale $\ell$. Cells actively regulate $\ell$ via…

Biological Physics · Physics 2018-06-08 Saroj Kumar Nandi

We use linear stability analysis and hybrid lattice Boltzmann simulations to study the dynamical behaviour of an active nematic confined in a channel made of viscoelastic material. We find that the quiescent, ordered active nematic is…

Soft Condensed Matter · Physics 2023-12-20 Francesco Mori , Saraswat Bhattacharyya , Julia M. Yeomans , Sumesh P. Thampi

In this work, we systematically investigate for the first time the nature of stress correlations in soft colloidal gel materials which support tensile and compressive forces as well as finite rolling torque, as a function of system…

Soft Condensed Matter · Physics 2023-08-09 Divas Singh Dagur , Chandana Mondal , Saikat Roy

Cell crawling crucially depends on the collective dynamics of the acto-myosin cytoskeleton. However, it remains an open question to what extent cell polarization and persistent motion depend on continuous regulatory mechanisms and…

Biological Physics · Physics 2023-08-11 Fenna Stegemerten , Karin John , Uwe Thiele

The physical gelation of colloids produces elastic structures that are commonly used to stabilize complex fluids in multiple industries. However, the ability to control the level of elastic modulus of these materials is limited by the…

Soft Condensed Matter · Physics 2021-12-21 Peng-Kai Kao , Michael J. Solomon , Mahesh Ganesan

Many active materials and biological systems are driven far from equilibrium by embedded agents that spontaneously generate forces and distort the surrounding material. Probing and characterizing these athermal fluctuations is essential for…

Materials Science · Physics 2015-05-18 D. A. Head , D. Mizuno

We study theoretically the phase diagram of compressible active polar gels such as the actin network of eukaryotic cells. Using generalized hydrodynamics equations, we perform a linear stability analysis of the uniform states in the case of…

Soft Condensed Matter · Physics 2009-11-13 R. Voituriez , J. F. Joanny , J. Prost

Active matter embraces systems that self-organize at different length and time scales, often exhibiting turbulent flows. Here, we use a quasi-two-dimensional nematically ordered layer of a protein-based active gel to experimentally…

Soft Condensed Matter · Physics 2017-11-01 Pau Guillamat , Jordi Ignés-Mullol , Francesc Sagués

The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular…

Statistical Mechanics · Physics 2015-05-13 C. Loverdo , O. Benichou , M. Moreau , R. Voituriez

Amoeboid cell migration is characterized by frequent changes of the direction of motion and resembles a persistent random walk on long time scales. Although it is well known that cell migration is typically driven by the actin cytoskeleton,…

Biological Physics · Physics 2021-06-09 Nicolas Ecker , Karsten Kruse

We use numerical simulations to study the dynamics of dense assemblies of self-propelled particles in the limit of extremely large, but finite, persistence times. In this limit, the system evolves intermittently between mechanical…

Soft Condensed Matter · Physics 2023-06-09 Yann-Edwin Keta , Rituparno Mandal , Peter Sollich , Robert L. Jack , Ludovic Berthier

Many organisms have an elastic skeleton that consists of a closed shell of epithelial cells that is filled with fluid, and can actively regulate both elastic forces in the shell and hydrostatic pressure inside it. In this work we introduce…

Soft Condensed Matter · Physics 2023-10-13 Ajoy Maji , Yitzhak Rabin

Cell spreading and motility on an adhesive substrate are driven by the active physical forces generated by the actin cytoskeleton. We have recently shown that coupling curved membrane complexes to protrusive forces, exerted by the actin…

Soft Condensed Matter · Physics 2023-04-04 Shubhadeep Sadhukhan , Samo Penič , Aleš Iglič , Nir Gov

The Dynamic Template model of biological cell membranes and the cytoplasm as spatially organised fluid layers is extended to plant cells, and is shown to offer a feasible shear driven mechanism for the co-alignment of internal and external…

General Physics · Physics 2008-07-15 J. T. Lofthouse

Like emulsions, pastes and many other forms of soft condensed matter, aqueous foams present slow mechanical relaxations when subjected to a stress too small to induce any plastic flow. To identify the physical origin of this viscoelastic…

Soft Condensed Matter · Physics 2016-08-16 S. Vincent-Bonnieu , R. Höhler , S. Cohen-Addad

Active matter systems display a fascinating range of dynamical states, including stationary patterns and turbulent phases. While the former can be tackled with methods from the field of pattern formation, the spatio-temporal disorder of the…

Fluid Dynamics · Physics 2018-08-13 Martin James , Wouter J. T. Bos , Michael Wilczek

Embryonic tissues deform across broad spatial and temporal scales and relax stress through active rearrangements. A quantitative link between cell-scale activity, spatial forcing, and emergent tissue-scale mechanics remains incomplete.…

Biological Physics · Physics 2025-12-18 Sahil Islam , Mohd. Suhail Rizvi , Anupam Gupta
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