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We introduce a framework to build a survival/risk bump hunting model with a censored time-to-event response. Our Survival Bump Hunting (SBH) method is based on a recursive peeling procedure that uses a specific survival peeling criterion…

Methodology · Statistics 2015-11-24 Jean-Eudes Dazard , Michael Choe , Michael LeBlanc , J. Sunil Rao

Among the proposals for joint disease mapping, the shared component model has become more popular. Another recent advance to strengthen inference of disease data has been the extension of purely spatial models to include time and space-time…

Applications · Statistics 2020-05-04 Behzad Mahaki , Yadollah Mehrabi , Amir Kavousi , Volker J Schmid

Survival models capture the relationship between an accumulating hazard and the occurrence of a singular event stimulated by that accumulation. When the model for the hazard is sufficiently flexible survival models can accommodate a wide…

Methodology · Statistics 2024-03-04 Michael Betancourt

Cox proportional hazard model (CPH) is commonly used in clinical research for survival analysis. In quantitative medical imaging (radiomics) studies, CPH plays an important role in feature reduction and modeling. However, the underlying…

Quantitative Methods · Quantitative Biology 2019-06-27 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

We propose a constrained maximum partial likelihood estimator for dimension reduction in integrative (e.g., pan-cancer) survival analysis with high-dimensional covariates. We assume that for each population in the study, the hazard function…

Methodology · Statistics 2023-04-27 Aaron J. Molstad , Rohit K. Patra

Time-to-event prediction, e.g. cancer survival analysis or hospital length of stay, is a highly prominent machine learning task in medical and healthcare applications. However, only a few interpretable machine learning methods comply with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Hubert Baniecki , Bartlomiej Sobieski , Patryk Szatkowski , Przemyslaw Bombinski , Przemyslaw Biecek

Extreme value analysis is an essential methodology in the study of rare and extreme events, which hold significant interest in various fields, particularly in the context of environmental sciences. Models that employ the exceedances of…

Methodology · Statistics 2025-07-16 Lorenzo Dell'Oro , Carlo Gaetan

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Two challenging problems in the clinical study of cancer are the characterization of cancer subtypes and the classification of individual patients according to those subtypes. Statistical approaches addressing these problems are hampered by…

Methodology · Statistics 2012-02-28 John A. Dawson , Christina Kendziorski

The issue of spatial confounding between the spatial random effect and the fixed effects in regression analyses has been identified as a concern in the statistical literature. Multiple authors have offered perspectives and potential…

Methodology · Statistics 2023-01-18 Kori Khan , Catherine A. Calder

Multi-state models provide an extension of the usual survival/event-history analysis setting. In the medical domain, multi-state models give the possibility of further investigating intermediate events such as relapse and remission. In this…

Methodology · Statistics 2021-06-24 D. Manevski , H. Putter , M. Pohar Perme , E. F. Bonneville , J. Schetelig , L. C. de Wreede

In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox…

Applications · Statistics 2019-11-05 Satabdi Saha , Duchwan Ryu , Nader Ebrahimi

We address the problem of survival regression modelling with multivariate responses and nonlinear covariate effects. Our model extends the proportional hazards model by introducing several weakly-parametric elements: the marginal baseline…

Methodology · Statistics 2025-10-16 Na Lei , Mark A. Wolters , Wenqing He

Joint models for longitudinal and time-to-event data have seen many developments in recent years. Though spatial joint models are still rare and the traditional proportional hazards formulation of the time-to-event part of the model is…

Methodology · Statistics 2024-06-25 Anja Rappl , Thomas Kneib , Stefan Lang , Elisabeth Bergherr

Tumor shape is a key factor that affects tumor growth and metastasis. This paper proposes a topological feature computed by persistent homology to characterize tumor progression from digital pathology and radiology images and examines its…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Chul Moon , Qiwei Li , Guanghua Xiao

We propose a deep learning model - Probabilistic Prognostic Estimates of Survival in Metastatic Cancer Patients (PPES-Met) for estimating short-term life expectancy (3 months) of the patients by analyzing free-text clinical notes in the…

Artificial Intelligence · Computer Science 2018-07-17 Imon Banerjee , Michael Francis Gensheimer , Douglas J. Wood , Solomon Henry , Daniel Chang , Daniel L. Rubin

In low-resource settings, prevalence mapping relies on empirical prevalence data from a finite, often spatially sparse, set of surveys of communities within the region of interest, possibly supplemented by remotely sensed images that can…

Applications · Statistics 2015-05-27 Peter J. Diggle , Emanuele Giorgi

Epidemiologists commonly use regional aggregates of health outcomes to map mortality or incidence rates and identify geographic disparities. However, to detect health disparities across regions, it is necessary to identify "difference…

Methodology · Statistics 2025-05-14 Luca Aiello , Sudipto Banerjee

This study employs a robust analytical framework to uncover patterns in survival outcomes among breast cancer patients from diverse racial and geographical backgrounds. This research uses the SEER 2021 dataset to analyze breast cancer…

Machine Learning · Computer Science 2025-06-10 Ramisa Farha , Joshua O. Olukoya

Despite spatial econometrics is now considered a consolidated discipline, only in recent years we have experienced an increasing attention to the possibility of applying it to the field of discrete choices (e.g. Smirnov, 2010 for a recent…

Applications · Statistics 2019-08-02 A. G. Billé , G. Arbia
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