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Synthetic data provides a promising approach to address data scarcity for training machine learning models; however, adoption without proper quality assessments may introduce artifacts, distortions, and unrealistic features that compromise…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Rucha Deshpande , Tahsin Rahman , Miguel Lago , Adarsh Subbaswamy , Jana G. Delfino , Ghada Zamzmi , Elim Thompson , Aldo Badano , Seyed Kahaki

Machine learning has been widely adopted for medical image analysis in recent years given its promising performance in image segmentation and classification tasks. The success of machine learning, in particular supervised learning, depends…

Computer Vision and Pattern Recognition · Computer Science 2022-06-03 Chengliang Dai , Shuo Wang , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu

The imaging community has increasingly adopted machine learning (ML) methods to provide individualized imaging signatures related to disease diagnosis, prognosis, and response to treatment. Clinical neuroscience and cancer imaging have been…

Early detection of anomalies in medical images such as brain MRI is highly relevant for diagnosis and treatment of many conditions. Supervised machine learning methods are limited to a small number of pathologies where there is good…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Alexander Frotscher , Jaivardhan Kapoor , Thomas Wolfers , Christian F. Baumgartner

Anomaly detection and localization in medical images is a challenging task, especially when the anomaly exhibits a change of existing structures, e.g., brain atrophy or changes in the pleural space due to pleural effusions. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

Digitization techniques for biomedical images yield different visual patterns in radiological exams. These differences may hamper the use of data-driven approaches for inference over these images, such as Deep Neural Networks. Another…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Hugo Oliveira , Edemir Ferreira , Jefersson A. dos Santos

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Anomaly detection in visual data refers to the problem of differentiating abnormal appearances from normal cases. Supervised approaches have been successfully applied to different domains, but require an abundance of labeled data. Due to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-29 Dejan Stepec , Danijel Skocaj

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Guangqian Yang , Tong Ding , Wenlong Hou , Yue Xun , Ye Du , Qian Niu , Shujun Wang

Anomaly detection consists in identifying, within a dataset, those samples that significantly differ from the majority of the data, representing the normal class. It has many practical applications, e.g. ranging from defective product…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Pankaj Mishra , Claudio Piciarelli , Gian Luca Foresti

Building an accurate computer-aided diagnosis system based on data-driven approaches requires a large amount of high-quality labeled data. In medical imaging analysis, multiple expert annotators often produce subjective estimates about…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Khiem H. Le , Tuan V. Tran , Hieu H. Pham , Hieu T. Nguyen , Tung T. Le , Ha Q. Nguyen

Semi-supervised anomaly detection, which aims to improve the anomaly detection performance by using a small amount of labeled anomaly data in addition to unlabeled data, has attracted attention. Existing semi-supervised approaches assume…

Machine Learning · Statistics 2025-02-11 Hiroshi Takahashi , Tomoharu Iwata , Atsutoshi Kumagai , Yuuki Yamanaka

Medical image segmentation is a fundamental and critical step in many clinical approaches. Semi-supervised learning has been widely applied to medical image segmentation tasks since it alleviates the heavy burden of acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-08-29 Yichi Zhang , Rushi Jiao , Qingcheng Liao , Dongyang Li , Jicong Zhang

Although neural networks have proven very successful in a number of medical image analysis applications, their use remains difficult when targeting subtle tasks such as the identification of barely visible brain lesions, especially given…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Verónica Muñoz-Ramírez , Nicolas Pinon , Florence Forbes , Carole Lartizen , Michel Dojat

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

Machine Learning · Computer Science 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

This paper investigates an extremely challenging problem: barely-supervised volumetric medical image segmentation (BSS). A BSS training dataset consists of two parts: 1) a barely-annotated labeled set, where each labeled image contains only…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Zhiqiang Shen , Peng Cao , Junming Su , Jinzhu Yang , Osmar R. Zaiane

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

Medical image annotation is essential for diagnosing diseases, yet manual annotation is time-consuming, costly, and prone to variability among experts. To address these challenges, we propose an automated explainable annotation system that…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Basma Nasir , Tehseen Zia , Muhammad Nawaz , Catarina Moreira

We present a system for anomaly detection in histopathological images. In histology, normal samples are usually abundant, whereas anomalous (pathological) cases are scarce or not available. Under such settings, one-class classifiers trained…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Igor Zingman , Birgit Stierstorfer , Charlotte Lempp , Fabian Heinemann