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Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Pre-trained vision-language models learn massive data to model unified representations of images and natural languages, which can be widely applied to downstream machine learning tasks. In addition to zero-shot inference, in order to better…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Qian-Wei Wang , Yuqiu Xie , Letian Zhang , Zimo Liu , Shu-Tao Xia

CNN visualization and interpretation methods, like class-activation maps (CAMs), are typically used to highlight the image regions linked to class predictions. These models allow to simultaneously classify images and extract class-dependent…

Computer Vision and Pattern Recognition · Computer Science 2020-11-17 Soufiane Belharbi , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Annotating histopathological images is a time-consuming andlabor-intensive process, which requires broad-certificated pathologistscarefully examining large-scale whole-slide images from cells to tissues.Recent frontiers of transfer learning…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Dou Xu , Chang Cai , Chaowei Fang , Bin Kong , Jihua Zhu , Zhongyu Li

Large annotated datasets are vital for training segmentation models, but pixel-level labeling is time-consuming, error-prone, and often requires scarce expert annotators, especially in medical imaging. In contrast, coarse annotations are…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Le Zhang , Fuping Wu , Arun Thirunavukarasu , Kevin Bronik , Thomas Nichols , Bartlomiej W. Papiez

Convolutional Neural Networks (CNNs) provide excellent performance when used for image classification. The classical method of training CNNs is by labeling images in a supervised manner as in "input image belongs to this label" (Positive…

Machine Learning · Computer Science 2019-08-21 Youngdong Kim , Junho Yim , Juseung Yun , Junmo Kim

Deep neural networks have achieved remarkable success in a wide variety of natural image and medical image computing tasks. However, these achievements indispensably rely on accurately annotated training data. If encountering some…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Cheng Xue , Lequan Yu , Pengfei Chen , Qi Dou , Pheng-Ann Heng

One of the key challenges in the battle against the Coronavirus (COVID-19) pandemic is to detect and quantify the severity of the disease in a timely manner. Computed tomographies (CT) of the lungs are effective for assessing the state of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-15 Issam Laradji , Pau Rodriguez , Frederic Branchaud-Charron , Keegan Lensink , Parmida Atighehchian , William Parker , David Vazquez , Derek Nowrouzezahrai

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Pathological is crucial to cancer diagnosis. Usually, Pathologists draw their conclusion based on observed cell and tissue structure on histology slides. Rapid development in machine learning, especially deep learning have established…

Image and Video Processing · Electrical Eng. & Systems 2020-01-15 Jiangbo Shi , Zeyu Gao , Haichuan Zhang , Pargorn Puttapirat , Chunbao Wang , Xiangrong Zhang , Chen Li

Microscopy images from different imaging conditions, organs, and tissues often have numerous cells with various shapes on a range of backgrounds. As a result, designing a deep learning model to count cells in a source domain becomes…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Zuhui Wang

Reviewing radiology reports in emergency departments is an essential but laborious task. Timely follow-up of patients with abnormal cases in their radiology reports may dramatically affect the patient's outcome, especially if they have been…

Computation and Language · Computer Science 2018-12-06 Hamed Hassanzadeh , Mahnoosh Kholghi , Anthony Nguyen , Kevin Chu

Convolutional neural networks (CNNs) are extensively beneficial for medical image processing. Medical images are plentiful, but there is a lack of annotated data. Transfer learning is used to solve the problem of lack of labeled data and…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Sajjad Abbasi , Mohsen Hajabdollahi , Nader Karimi , Shadrokh Samavi , Shahram Shirani

The visual attributes of cells, such as the nuclear morphology and chromatin openness, are critical for histopathology image analysis. By learning cell-level visual representation, we can obtain a rich mix of features that are highly…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Bo Hu , Ye Tang , Eric I-Chao Chang , Yubo Fan , Maode Lai , Yan Xu

Positive Unlabeled (PU) learning is widely used in many applications, where a binary classifier is trained on the datasets consisting of only positive and unlabeled samples. In this paper, we improve PU learning over state-of-the-art from…

Machine Learning · Computer Science 2020-04-22 Liwei Jiang , Dan Li , Qisheng Wang , Shuai Wang , Songtao Wang

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Deep learning has proven to be an essential tool for medical image analysis. However, the need for accurately labeled input data, often requiring time- and labor-intensive annotation by experts, is a major limitation to the use of deep…

Computer Vision and Pattern Recognition · Computer Science 2020-01-28 Darvin Yi , Endre Grøvik , Michael Iv , Elizabeth Tong , Greg Zaharchuk , Daniel Rubin

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

Most state-of-the-art instance segmentation methods have to be trained on densely annotated images. While difficult in general, this requirement is especially daunting for biomedical images, where domain expertise is often required for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Adrian Wolny , Qin Yu , Constantin Pape , Anna Kreshuk