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Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…

Neurons and Cognition · Quantitative Biology 2025-07-14 Sungwoo Ahn , Evie A. Malaia , Leonid L Rubchinsky

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

Electroencephalography (EEG)-based attention disorder research seeks to understand brain activity patterns associated with attention. Previous studies have mainly focused on identifying brain regions involved in cognitive processes or…

Neurons and Cognition · Quantitative Biology 2024-10-15 Debashis Das Chakladar , Foteini Simistira Liwicki , Rajkumar Saini

Attention Deficit Hyperactivity Disorder (ADHD) is a chronic mental and behavioral disorder that interferes with everyday activities and has three core symptoms: inattention, hyperactivity, and impulsivity. To help in reducing the effects…

Human-Computer Interaction · Computer Science 2020-05-21 Fatemah Husain

Attention-deficit/hyperactivity disorder (ADHD) is characterized by executive dysfunction and difficulties in processing emotional facial expressions, yet the large-scale neural dynamics underlying these impairments remain insufficiently…

Neurons and Cognition · Quantitative Biology 2025-12-16 Saghar Vosough , Gian Candrian , Johannes Kasper , Hossam Abdel Rehim , Dominique Eich , Andreas Mueller , Lutz Jäncke

Recently, the application of deep learning models to diagnose neuropsychiatric diseases from brain imaging data has received more and more attention. However, in practice, exploring interactions in brain functional connectivity based on…

Machine Learning · Computer Science 2022-06-29 Sartaj Ahmed Salman , Zhichao Lian , Milad Taleby Ahvanooey , Hiroki Takahashi , Yuduo Zhang

To examine associations between screen time and anxiety, depression, behavior or conduct problems, and ADHD among children and adolescents during the pandemic, and to assess whether physical activity, sleep duration, and bedtime regularity…

Neurons and Cognition · Quantitative Biology 2026-05-18 Ying Dai , Na Ouyang

Depression and Attention Deficit Hyperactivity Disorder (ADHD) stand out as the common mental health challenges today. In affective computing, speech signals serve as effective biomarkers for mental disorder assessment. Current research,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-05 Shuanglin Li , Siyang Song , Rajesh Nair , Syed Mohsen Naqvi

The brain's functional connectivity fluctuates over time instead of remaining steady in a stationary mode even during the resting state. This fluctuation establishes the dynamical functional connectivity that transitions in a non-random…

Neurons and Cognition · Quantitative Biology 2022-03-28 Shikuang Deng , Jingwei Li , B. T. Thomas Yeo , Shi Gu

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder in children, characterized by difficulties in attention, hyperactivity, and impulsivity. Early and accurate diagnosis of ADHD is critical for effective…

Signal Processing · Electrical Eng. & Systems 2025-04-08 Md Bayazid Hossain , Md Anwarul Islam Himel , Md Abdur Rahim , Shabbir Mahmood , Abu Saleh Musa Miah , Jungpil Shin

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and behavioral patterns. Eye movement data offers a non-invasive diagnostic tool for ASD detection, as it is inherently…

Machine Learning · Computer Science 2026-01-12 Zhanpei Huang , Taochen chen , Fangqing Gu , Yiqun Zhang

Human brain functional connectivity (FC) is often measured as the similarity of functional MRI responses across brain regions when a brain is either resting or performing a task. This paper aims to statistically analyze the dynamic nature…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Autism spectrum disorder is a neuro-developmental disorder characterized by abnormalities of neural synchronization. In this study, functional near infrared spectroscopy (fNIRS) is used to study the difference in functional connectivity in…

Neurons and Cognition · Quantitative Biology 2013-09-24 Huilin Zhu , Yuebo Fan , Huan Guo , Dan Huang , Sailing He

Dynamic functional connectivity (dFC) is ubiquitously observed in the brain, but why functional networks should remain dynamic even at rest is unclear. We asked whether temporal reconfiguration becomes advantageous when keeping a functional…

Biological Physics · Physics 2026-04-14 Simachew Abebe Mengiste , Demian Battaglia

The human brain dynamically integrated and configured information to adapt to the environment. To capture these changes over time, dynamic second-order functional connectivity was typically used to capture transient brain patterns. However,…

Neurons and Cognition · Quantitative Biology 2025-07-01 Qiang Li , Vince D. Calhoun , Armin Iraji

We investigate the relationship of resting-state fMRI functional connectivity estimated over long periods of time with time-varying functional connectivity estimated over shorter time intervals. We show that using Pearson's correlation to…

Neurons and Cognition · Quantitative Biology 2016-09-08 Richard F. Betzel , Makoto Fukushima , Ye He , Xi-Nian Zuo , Olaf Sporns

In modern society, Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the common mental diseases discovered not only in children but also in adults. In this context, we propose a ADHD diagnosis transformer model that can effectively…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Byunggun Kim , Younghun Kwon

The primary goal of this paper is to develop a method that quantifies how activity in one brain region can explain future activity in another region. Here, we propose the mixed effects spectral vector-autoregressive (ME-SpecVar) model to…

Applications · Statistics 2022-10-07 Anastasiia Malinovskaia

Understanding the dynamic nature of brain connectivity is critical for elucidating neural processing, behavior, and brain disorders. Traditional approaches such as sliding-window correlation (SWC) characterize time-varying undirected…

Neurons and Cognition · Quantitative Biology 2026-02-19 Nan Xu , Xiaodi Zhang , Wen-Ju Pan , Jeremy L. Smith , Eric H. Schumacher , Jason W. Allen , Vince D. Calhoun , Shella D. Keilholz