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Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

Deep Learning has a hierarchical network architecture to represent the complicated feature of input patterns. The adaptive structural learning method of Deep Belief Network (DBN) has been developed. The method can discover an optimal number…

Neural and Evolutionary Computing · Computer Science 2018-08-28 Shin Kamada , Takumi Ichimura , Toshihide Harada

Even though convolutional neural networks have become the method of choice in many fields of computer vision, they still lack interpretability and are usually designed manually in a cumbersome trial-and-error process. This paper aims at…

Computer Vision and Pattern Recognition · Computer Science 2019-12-12 Maria Ximena Bastidas Rodriguez , Adrien Gruson , Luisa F. Polania , Shin Fujieda , Flavio Prieto Ortiz , Kohei Takayama , Toshiya Hachisuka

How can we find interpretable, domain-appropriate models of natural phenomena given some complex, raw data such as images? Can we use such models to derive scientific insight from the data? In this paper, we propose some methods for…

Machine Learning · Computer Science 2024-02-06 Christopher J. Soelistyo , Alan R. Lowe

Apart from discriminative models for classification and object detection tasks, the application of deep convolutional neural networks to basic research utilizing natural imaging data has been somewhat limited; particularly in cases where a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 R. Ian Etheredge , Manfred Schartl , Alex Jordan

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Representation learning constitutes a pivotal cornerstone in contemporary deep learning paradigms, offering a conduit to elucidate distinctive features within the latent space and interpret the deep models. Nevertheless, the inherent…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Siyuan Dai , Kai Ye , Kun Zhao , Ge Cui , Haoteng Tang , Liang Zhan

While state-of-the-art models for breast cancer detection leverage multi-view mammograms for enhanced diagnostic accuracy, they often focus solely on visual mammography data. However, radiologists document valuable lesion descriptors that…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Gil Ben-Artzi , Feras Daragma , Shahar Mahpod

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Investigating relationships between variables in multi-dimensional data sets is a common task for data analysts and engineers. More specifically, it is often valuable to understand which ranges of which input variables lead to particular…

Machine Learning · Computer Science 2020-09-14 Johannes Knittel , Andres Lalama , Steffen Koch , Thomas Ertl

Computer aided detection and diagnosis systems based on deep learning have shown promising performance in breast cancer detection. However, there are cases where the obtained results lack justification. In this study, our objective is to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Imane Nedjar , Mohammed Brahimi , Said Mahmoudi , Khadidja Abi Ayad , Mohammed Amine Chikh

Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…

Computer Vision and Pattern Recognition · Computer Science 2018-06-18 Sungmin Rhee , Seokjun Seo , Sun Kim

Physical experiments often involve multiple imaging representations, such as X-ray scans and microscopic images. Deep learning models have been widely used for supervised analysis in these experiments. Combining different image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Nadav Schneider , Muriel Tzdaka , Galit Sturm , Guy Lazovski , Galit Bar , Gilad Oren , Raz Gvishi , Gal Oren

While deep learning has achieved great success in many fields, one common criticism about deep learning is its lack of interpretability. In most cases, the hidden units in a deep neural network do not have a clear semantic meaning or…

Genomics · Quantitative Biology 2019-06-04 Tianle Ma , Aidong Zhang

While neural networks for learning representation of multi-view data have been previously proposed as one of the state-of-the-art multi-view dimension reduction techniques, how to make the representation discriminative with only a small…

Machine Learning · Computer Science 2018-11-13 Vahid Noroozi , Sara Bahaadini , Lei Zheng , Sihong Xie , Weixiang Shao , Philip S. Yu

Machine learning algorithms often produce models considered as complex black-box models by both end users and developers. They fail to explain the model in terms of the domain they are designed for. The proposed Iterative Visual Logical…

Machine Learning · Computer Science 2021-07-13 Sridevi Narayana Wagle , Boris Kovalerchuk

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering