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Anatomical landmark detection in medical images is essential for various clinical and research applications, including disease diagnosis and surgical planning. However, manual landmark annotation is time-consuming and requires significant…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Soorena Salari , Arash Harirpoush , Hassan Rivaz , Yiming Xiao

Due to the lack of standardized 3D cephalometric analytic methodology, 2D cephalograms synthesized from 3D cone-beam computed tomography (CBCT) volumes are widely used for cephalometric analysis in dental CBCT systems. However, compared…

Image and Video Processing · Electrical Eng. & Systems 2021-03-23 Yixing Huang , Fuxin Fan , Christopher Syben , Philipp Roser , Leonid Mill , Andreas Maier

Left ventricular (LV) indicator measurements following clinical echocardiog-raphy guidelines are important for diagnosing cardiovascular disease. Alt-hough existing algorithms have explored automated LV quantification, they can struggle to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Tuo Liu , Qinghan Yang , Yu Zhang , Rongjun Ge , Yang Chen , Guangquan Zhou

Linear measurements of the left ventricle (LV) in the Parasternal Long Axis (PLAX) view using B-mode echocardiography are crucial for cardiac assessment. These involve placing 4-6 landmarks along a virtual scanline (SL) perpendicular to the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Durgesh K. Singh , Ahcene Boubekki , Qing Cao , Svein Arne Aase , Robert Jenssen , Michael Kampffmeyer

Rapid advances in 3D model scanning have enabled the mass digitization of dental clay models. However, most clinicians and researchers continue to use manual morphometric analysis methods on these models such as landmarking. This is a…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Artur Agaronyan , HyeRan Choo , Marius Linguraru , Syed Muhammad Anwar

In forensic craniofacial identification and in many biomedical applications, craniometric landmarks are important. Traditional methods for locating landmarks are time-consuming and require specialized knowledge and expertise. Current…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Ravi Shankar Prasad , Nandani Sharma , Dinesh Singh

Large-scale multimodal language models (LMMs) have achieved remarkable success in general domains. However, the exploration of diagnostic language models based on multimodal cephalometric medical data remains limited. In this paper, we…

Artificial Intelligence · Computer Science 2023-07-18 Lei Ma , Jincong Han , Zhaoxin Wang , Dian Zhang

Cerebral Microbleeds (CMBs) are chronic deposits of small blood products in the brain tissues, which have explicit relation to various cerebrovascular diseases depending on their anatomical location, including cognitive decline,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Jun-Ho Kim , Young Noh , Haejoon Lee , Seul Lee , Woo-Ram Kim , Koung Mi Kang , Eung Yeop Kim , Mohammed A. Al-masni , Dong-Hyun Kim

Background:Cognitive assessments represent the most common clinical routine for the diagnosis of Alzheimer's Disease (AD). Given a large number of cognitive assessment tools and time-limited office visits, it is important to determine a…

Quantitative Methods · Quantitative Biology 2020-11-16 Bo Peng , Xiaohui Yao , Shannon L. Risacher , Andrew J. Saykin , Li Shen , Xia Ning

Manual annotation of anatomical landmarks on 3D facial scans is a time-consuming and expertise-dependent task, yet it remains critical for clinical assessments, morphometric analysis, and craniofacial research. While several deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Ali Shadman Yazdi , Annalisa Cappella , Benedetta Baldini , Riccardo Solazzo , Gianluca Tartaglia , Chiarella Sforza , Giuseppe Baselli

This paper addresses the challenge of localization of anatomical landmarks in knee X-ray images at different stages of osteoarthritis (OA). Landmark localization can be viewed as regression problem, where the landmark position is directly…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Aleksei Tiulpin , Iaroslav Melekhov , Simo Saarakkala

Deep neural networks yield promising results in a wide range of computer vision applications, including landmark detection. A major challenge for accurate anatomical landmark detection in volumetric images such as clinical CT scans is that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 Tianyu Ma , Ajay Gupta , Mert R. Sabuncu

Deep learning networks have shown promising performance for accurate object localization in medial images, but require large amount of annotated data for supervised training, which is expensive and expertise burdensome. To address this…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Wenhui Lei , Wei Xu , Ran Gu , Hao Fu , Shaoting Zhang , Guotai Wang

Artificial intelligence (AI) technology is increasingly used for digital orthodontics, but one of the challenges is to automatically and accurately detect tooth landmarks and axes. This is partly because of sophisticated geometric…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Guangshun Wei , Zhiming Cui , Jie Zhu , Lei Yang , Yuanfeng Zhou , Pradeep Singh , Min Gu , Wenping Wang

Anatomical landmark correspondences in medical images can provide additional guidance information for the alignment of two images, which, in turn, is crucial for many medical applications. However, manual landmark annotation is…

Computer Vision and Pattern Recognition · Computer Science 2020-04-09 Monika Grewal , Timo M. Deist , Jan Wiersma , Peter A. N. Bosman , Tanja Alderliesten

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Craniofacial profile is one of the anatomical causes of obstructive sleep apnea(OSA). By medical research, cephalometry provides information on patients' skeletal structures and soft tissues. In this work, a novel approach to cephalometric…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Hei-Long Chan , Hoi-Man Yuen , Chun-Ting Au , Kate Ching-Ching Chan , Albert Martin Li , Lok-Ming Lui

The success of deep learning methods relies on the availability of a large number of datasets with annotations; however, curating such datasets is burdensome, especially for medical images. To relieve such a burden for a landmark detection…

Computer Vision and Pattern Recognition · Computer Science 2021-03-09 Qingsong Yao , Quan Quan , Li Xiao , S. Kevin Zhou

Purpose: Interpreting chest radiographs (CXR) remains challenging due to the ambiguity of overlapping structures such as the lungs, heart, and bones. To address this issue, we propose a novel method for extracting fine-grained anatomical…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Constantin Seibold , Alexander Jaus , Matthias A. Fink , Moon Kim , Simon Reiß , Ken Herrmann , Jens Kleesiek , Rainer Stiefelhagen

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil